Results 241 to 250 of about 5,845 (290)
Hyperglycemia-Reduced Platelet-Derived Growth Factor-BB Expression Impairs Corneal Wound Healing in Diabetic Mice. [PDF]
Zhang Y +9 more
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IN-VIVO AND IN-VITRO EFFECTS OF POLYVINYLPYRROLIDONE ON PLATELET ADHESIVENESS IN HUMAN BLOOD [PDF]
Intravenous infusion of 500 ml. 6% polyvinylpyrrolidone (P.V.P. (Mw 40,000) in isotonic saline solution over a 2-hour period significantly diminished platelet adhesiveness in eight subjects from 27% before infusion to as low as 10% at the end of the ...
Smet, Guido +2 more
exaly +2 more sources
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Seminars in Cell Biology, 1995
The response to vascular injury involves attachment and aggregation of platelets, coupled with initiation of the coagulation cascade. These inter-related processes ensure that the vessel injury is rapidly blocked with an aggregated clump of platelets that is then stabilized by a crosslinked fibrin matrix.
M J, Williams +3 more
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The response to vascular injury involves attachment and aggregation of platelets, coupled with initiation of the coagulation cascade. These inter-related processes ensure that the vessel injury is rapidly blocked with an aggregated clump of platelets that is then stabilized by a crosslinked fibrin matrix.
M J, Williams +3 more
openaire +2 more sources
Platelet Adhesiveness to Glass
Thrombosis and Haemostasis, 1979Summary1. When anticoagulated blood is placed in a rotating glass flask, the blood/air interface initiates platelet aggregation, and the aggregates are trapped on the flask wall, without adhering to it, by the thin film of blood which forms during rotation. The interface; allows CO2 loss so that the pH of the rotating blood rises markedly and this rise
R L, Page, J R, Mitchell
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Adhesive signaling in platelets
Current Opinion in Cell Biology, 1994The anucleate platelet must perform its hemostatic functions in the absence of transcriptional regulation. Central among these functions is cell adhesion, which is mediated by multiple specialized plasma membrane receptors. The adhesive function of one of the key receptors, integrin alpha IIb beta 3, is regulated by intracellular signals triggered by ...
S J, Shattil, M H, Ginsberg, J S, Brugge
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ADHESION OF PLATELETS TO SUBENDOTHELIUM
Annals of the New York Academy of Sciences, 1972SummaryEndothelium provides the physiologic nonthrombogenic surface in vivo. Connective tissue components underneath the endothelial lining form the subendo‐thelium. The subendothelial surface appears far less thrombogenic than collagen fibers. Platelet adhesion to subendothelium as an entity is greatly enhanced by the presence of other blood cells, by
H R, Baumgartner, C, Haudenschild
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Thrombosis Research, 2011
Platelets play a central role in maintaining hemostasis mainly by binding to subendothelial collagen exposed upon vascular injury, thereby initiating thrombus formation. Platelets can bind directly to the exposed collagen through two major receptors i.e. the integrin a2b1 and glycoprotein (GP) VI.
Benedicte P, Nuyttens +3 more
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Platelets play a central role in maintaining hemostasis mainly by binding to subendothelial collagen exposed upon vascular injury, thereby initiating thrombus formation. Platelets can bind directly to the exposed collagen through two major receptors i.e. the integrin a2b1 and glycoprotein (GP) VI.
Benedicte P, Nuyttens +3 more
openaire +2 more sources
Studies of Platelet Adhesiveness with Reference to Platelet Age
Scandinavian Journal of Haematology, 1969In this study, autologous human platelets labelled with 31Cr were infused in healthy volunteers and their adhesiveness to glass was repeatedly measured during their survival in the circulation using the Salzman's technique. 51Cr‐specific activity was determined seperately for the ‘adhesive’ and ‘non‐adhesive’ platelets and expressed as a ratio of the ...
Z, Rolovic, M G, Baldini
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A Standardized Test of Platelet Adhesiveness
American Journal of Clinical Pathology, 1972An inexpensive and easily constructed glass bead column for determining adhesiveness in vitro is described. The column consists of a flexible paper sipping straw to which a measured quantity of glass beads is added. The column is perfused with heparinized blood at a constant rate of flow.
L R, Zacharski, O R, McIntyre
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The molecular mechanism of platelet adhesion
Australian and New Zealand Journal of Medicine, 1995Abstract:One of the most primitive of host‐defence mechanisms is haemostasis, the ability to control blood loss. In response to vascular trauma, platelets rapidly adhere to the exposed subendothelial matrix, a process that ultimately results in the sealing of the vessel by a plug of platelets stabilised by fibrin.
M C, Berndt +6 more
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