Results 31 to 40 of about 12,292 (326)

Neutrophil swarms require LTB4 and integrins at sites of cell death in vivo [PDF]

, 2013
Neutrophil recruitment from blood to extravascular sites of sterile or infectious tissue damage is a hallmark of early innate immune responses, and the molecular events leading to cell exit from the bloodstream have been well defined1,2. Once outside the
Afonso, P., Angermann, B., Germain, R., Kastenmüller, W., Lämmermann, T., Parent, C., Wang, J.   +6 more
core   +2 more sources

A doença de Chagas como um modelo mecanicista para testar uma nova hipótese [PDF]

, 2008
The association between depression and cardiovascular disease is well documented. Nevertheless, the process through which they are linked remains unknown, as does the direction of this relationship.
CORREIA, Dalmo, DIAS, João Carlos Pinto, FARKOUH, Michael E., IANNI, Barbara, LOPES, Neuza, MADY, Charles, MOSOVICH, Serge A.   +6 more
core   +2 more sources

Translating proof-of-concept for platelet slip into improved antithrombotic therapeutic regimens

Platelets
Platelets are central to thrombosis. Research at the intersection of biological and physical sciences provides proof-of-concept for shear rate-dependent platelet slip at vascular stenosis and near device surfaces.
Scott J. Denardo, Pavlos P. Vlachos, Brett A. Meyers, Reza Babakhani-Galangashi, Lin Wang, Zejin Gao, James E. Tcheng   +6 more
doaj   +1 more source

The influence of protein adsorption on interactions of cultured human endothelial cells with polymers [PDF]

, 1987
A systematic study of the effects of polymer surface properties on the interaction with human endothelial cells (HEC) may lead to the development of small-diameter vascular grafts.
Aken, W.G. van, Bantjes, A., Beugeling, T., Detmers, J.P., Feijen, J., Vreriks, C.M., Wachem, P.B. van   +6 more
core   +4 more sources

Cell Adhesion Mechanisms in Platelets [PDF]

Arteriosclerosis, Thrombosis, and Vascular Biology, 2008
At sites of vascular injury, platelets come into contact with the subendothelial extracellular matrix which triggers their activation and the formation of a hemostatic plug. This process is crucial for normal hemostasis, but may also lead to pathological thrombus formation causing diseases such as myocardial infarction or stroke. The initial capture of
David, Varga-Szabo, Irina, Pleines, Bernhard, Nieswandt   +2 more
openaire   +2 more sources

Thrombospondin-1-Derived Peptide RFYVVMWK Improves the Adhesive Phenotype of CD34 Cells from Atherosclerotic Patients with Type 2 Diabetes

Cell Transplantation, 2017
CD34 + progenitor cells are growing in use for vascular repair. However, in diabetic individuals with cardiovascular diseases, these cells have dysfunctional engraftment capabilities, which compromise their use for autologous cell therapy.
Sylvie Cointe, Éric Rhéaume, Catherine Martel, Olivier Blanc-Brude, Evemie Dubé, Florence Sabatier, Françoise Dignat-George, Jean-Claude Tardif, Arnaud Bonnefoy   +8 more
doaj   +1 more source

Safety and Efficacy of Anticoagulation Therapy in Paediatric Patients With Solid Tumours or Lymphomas at Risk of Thrombocytopenia: A Retrospective Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Patients with solid tumours or lymphomas have an increased risk of thromboembolism (TE) and thrombocytopenia. Evidence‐based strategies for anticoagulation therapy (ACT) for patients with thrombocytopenia are limited. We examined the impact of thrombocytopenia on ACT administration and bleeding incidence in children with solid ...
Andrés Felipe Fajardo, Katherine Talpin, Bishal Harry, Uma H. Athale, Anthony K. C. Chan, Mihir D. Bhatt   +5 more
wiley   +1 more source

Composite Hydrogel Dressings with Enhanced Mechanical Properties and Anti-Inflammatory Ability for Effectively Promoting Wound Repair

International Journal of Nanomedicine, 2023
Yuqin Feng,1,2 Si Qin,3 Huarun Li,3 Yemei Yang,1 Yushi Zheng,1 Hongsheng Liu,4 Wei Yin Yap,1,5 Xianyi Zhou,1 Ju Wen2,3 1Department of Dermatology, the Third Affiliated Hospital of Southern Medical University, Guangzhou, 510630, People’s Republic of China;
Feng Y, Qin S, Li H, Yang Y, Zheng Y, Liu H, Yap WY, Zhou X, Wen J   +8 more
doaj  

Cilengitide down-modulates invasiveness and vasculogenic mimicry of neuropilin-1 expressing melanoma cells through the inhibition of αvβ5 integrin. [PDF]

, 2014
During melanoma progression, tumour cells show increased adhesiveness to the vascular wall, invade the extracellular matrix (ECM) and frequently form functional channels similar to vascular vessels (vasculogenic mimicry).
Borges, Bosserhoff, Cheng, Desch, Ellis, Emmett, Guo, Hansel, Harburger, Hofmann, Jin, Kim, Kirmse, Kuphal, Lacal, Lacal, Lacal, Latil, Lewis, Lu, Mas-Moruno, Misra, Murga, Oliveira-Ferrer, Paulis, Pellet-Many, Pinon, Preissner, Reardon, Reardon, Ria, Ricono, Robinson, Ruffini, Ruffini, Ruffini, Rybak, Schaft, Seftor, Sennino, Smith, Snuderl, Somanath, Tentori, Tentori, Tentori, Vartanian, Vartanian, Vogetseder, Wei   +49 more
core   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source