Shape‐Morphing Nanoengineered Hydrogel Ribbons as Hemostats
This study introduces a self‐assembling, shape‐morphing nanoengineered hydrogel ribbon system that rapidly forms porous aggregates in situ for efficient hemostasis in trauma and surgical applications. Abstract Rapid and effective hemorrhage control remains a major challenge in trauma and surgical care, particularly for complex or noncompressible wounds.
Ryan Davis Jr +9 more
wiley +1 more source
Relevance of Polypill for Primary Prevention of Cardiovascular Diseases in the 21st Century
Polypill, as a fixed dose combination of cardioprotective therapies, has been developed for primary prevention of cardiovascular diseases (CVD) with the premise that raised blood pressure, LDL cholesterol, and platelet adhesiveness are the prime culprits.
Rajeev Gupta
doaj +1 more source
An Ionic Gelation Powder for Ultrafast Hemostasis and Accelerated Wound Healing
An ultrafast ionic gelation‐activated hemostatic powder (AGCL) forms a hydrogel within ≈1 s upon contact with blood‐derived calcium ions. The AGCL powder enables rapid hemorrhage control, strong tissue adhesion, and enhanced healing. The powder's pre‐crosslinked polymer network ensures high blood uptake and stability, offering effective treatment for ...
Youngju Son +12 more
wiley +1 more source
Perioperative antiplatelet therapy: the case for continuing therapy in patients at risk of myocardial infarction [PDF]
Recent clinical data show that the risk of coronary thrombosis after antiplatelet drugs withdrawal is much higher than that of surgical bleeding if they are continued.
Chassot, P.-G +2 more
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A self‐gelling PG@PAC (POD/Gel‐CDH@PA/CHX) powder is developed for infected burn care in austere settings. Upon contact with wound exudate, it instantly forms an adhesive hydrogel, providing simultaneous hemostasis, broad‐spectrum antibacterial activity, reactive oxygen species scavenging, and immunomodulation. In a murine model of S.
Liping Zhang +14 more
wiley +1 more source
Splanchnic vein thrombosis in myeloproliferative neoplasms: Pathophysiology and molecular mechanisms of disease [PDF]
Myeloproliferative neoplasms (MPNs) are the most common underlying prothrombotic disorder found in patients with splanchnic vein thrombosis (SVT). Clinical risk factors for MPN-associated SVTs include younger age, female sex, concomitant hypercoagulable ...
How, Joan, Oh, Stephen T, Zhou, Amy
core +2 more sources
Nano‐ and Micro‐Sized Solid Materials Used as Antiviral Agents
Due to the rise of viral infections in humans and possible viral outbreaks, the use of nano‐ or micro‐sized materials as antiviral agents is rapidly increasing. This review explores their antiviral properties against RNA and DNA viruses, either as a prevention or a treatment tool, by delving into their mechanisms of action and how to properly assess ...
Orfeas‐Evangelos Plastiras +6 more
wiley +1 more source
Bioprinting Organs—Science or Fiction?—A Review From Students to Students
Bioprinting artificial organs has the potential to revolutionize the medical field. This is a comprehensive review of the bioprinting workflow delving into the latest advancements in bioinks, materials and bioprinting techniques, exploring the critical stages of tissue maturation and functionality.
Nicoletta Murenu +18 more
wiley +1 more source
Growth Hormone‐Loaded 3D Printed Silk Fibroin‐Cellulose Dressings for Ischemic Wounds
3D‐printed wound dressings combining carboxymethyl cellulose, silk fibroin, and growth hormone accelerate healing in diabetic ulcers. These bioactive, customizable dressings enhance angiogenesis, cellular proliferation, and immune modulation. Proteomic analysis reveals activation of regenerative pathways and reduced fibrosis, highlighting their ...
Maria Pita‐Vilar +7 more
wiley +1 more source
The Recent History of Platelets in Thrombosis and Other Disorders [PDF]
The transcript of a Witness Seminar held by the Wellcome Trust Centre for the History of Medicine at UCL, London, on 25 November 2003. Introduction by Professor Tom Meade, London School of Hygiene and Tropical Medicine.First published by the Wellcome ...
Reynolds, LA, Tansey, EM
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