Results 261 to 270 of about 1,089,521 (397)

Predictive Value of Platelet Aggregation Tests in Recurrent Cerebral Ischemia and Major Bleeding. [PDF]

Med Sci Monit
Ishiguro M, Kurokawa Y, Tanooka A, Nagamine T.   +3 more
europepmc   +1 more source

Clopidogrel for Coronary Stenting Response Variability, Drug Resistance, and the Effect of Pretreatment Platelet Reactivity

Circulation, 2003
P. Gurbel, K. Bliden, B. L. Hiatt, C. O'connor   +3 more
semanticscholar   +1 more source

Modifying Glucose Metabolism Reverses Memory Defects of Alzheimer's Disease Model at Late Stages

Advanced Science, EarlyView.
Using spatial transcriptomics, we show that ferul enanthate (SL‐ZF‐01) reverses episodic‐like memory deficits in aged, but not young, Alzheimer’s disease (AD) mice. SL restores glucose metabolism and Glucose Transporter 1/3 expression via an ‘Aging‐AD‐Rescue’ pattern, rescuing deficits seen in aged AD mice.
Fang Liu, Yiyu‐Li Tang, Zong‐Bo Zhang, Ya‐Hong Tan, Si‐Hui Lin, Ni‐Ya Wang, Jin‐Nan Li, Zhi‐Jie Pan, Jian‐Feng Li, Jing‐Fei Huang, Yu‐Qiang Ding, Chun‐Ming Guo, Lin Xu, Cheng Peng, Qi‐Xin Zhou   +14 more
wiley   +1 more source

Coactivation of two different G protein-coupled receptors is essential for ADP-induced platelet aggregation.

Proceedings of the National Academy of Sciences of the United States of America, 1998
Jianguo Jin, S. Kunapuli
semanticscholar   +1 more source

Mitochondrial Calcium Uniporter Drives Chemoresistance in Pancreatic Cancer via Glutathione‐Mediated Stemness Maintenance

Advanced Science, EarlyView.
PDAC has a poor prognosis due to chemoresistance. We revealed that MCU upregulation is associated with chemoresistance and stemness in PDAC. MCU‐mediated Ca2+ influx induced ER stress, activating the PERK‐ATF4/NRF2 axis to enhance PSAT1/SLC711 expression and glutathione synthesis, reducing ROS and maintaining stemness.
Zekun Li, Chenyang Meng, Guangcong Shen, Yueying Shan, Junjin Wang, Diliyaer Abudukeremu, Rui Zhao, Bo Ni, Chao Xu, Xiaofan Guo, Jun Yu, Kaiyuan Wang, Shengyu Yang, YunZhan Li, Yongjie Xie, Tianxing Zhou, Jihui Hao, Xiuchao Wang   +17 more
wiley   +1 more source

The role of von Willebrand factor and fibrinogen in platelet aggregation under varying shear stress.

Journal of Clinical Investigation, 1991
Y. Ikeda, M. Handa, K. Kawano, T. Kamata, M. Murata, Y. Araki, H. Anbo, Y. Kawai, Kiyoaki Watanabe, I. Itagaki, Kiyotaka Sakai, Zaverio M. Ruggerill   +11 more
semanticscholar   +1 more source

Platelet Rubicon Bidirectional Regulation of GPVI and Integrin αIIbβ3 Signaling Mitigates Stroke Infarction Without Compromising Hemostasis

Advanced Science, EarlyView.
This study identifies Rubicon as a key platelet protein that bidirectionally regulates GPVI and integrin αIIbβ3 signaling. Platelet Rubicon protects against cerebral ischemia‐reperfusion injury by limiting infarction without increasing hemorrhage.
Xiaoyan Chen, Jingke Li, Yangyang Liu, Li Li, Xin Deng, Yilin Sheng, Xianyu Zhu, Xiao Jiang, Wei Li, Xueli Cai, Qiming Sun, Hu Hu   +11 more
wiley   +1 more source

Vorticity-Facilitated Platelet Aggregation: a High Expansion-Ratio Stenotic Microfluidic Platform Unravels the Role of Complex Flow Dynamics in Arterial Thrombosis. [PDF]

Adv Healthc Mater
Ren J, Abidin NAZ, Sun A, Gao R, Chen Y, Nasser A, Wang Z, Zhao YC, Dupuy A, Waterhouse A, Su QP, Vigolo D, Wu MCL, Ju LA.   +13 more
europepmc   +1 more source

Complete reversal of acid-induced acute lung injury by blocking of platelet-neutrophil aggregation.

Journal of Clinical Investigation, 2006
A. Zarbock, K. Singbartl, K. Ley
semanticscholar   +1 more source

Aspirin delays hyperthermia-induced platelet aggregation in pial microvessels of the mouse

, 1994
Farouk El‐Sabban, M. Fahim, Mohammed Hasan, Sukhi Singh   +3 more
openalex   +1 more source