Results 101 to 110 of about 74,252 (240)

Multiscale simulation of blood flow in brain arteries with an aneurysm [PDF]

arXiv, 2011
Interfacing atomistic-based with continuum-based simulation codes is now required in many multiscale physical and biological systems. We present the first results from coupled atomistic-continuum simulations on 190,000 processors. Platelet aggregation in the patient-specific model of an aneurysm has been modeled using a high-order spectral/hp element ...
arxiv  

The Deepest Blue: Major Advances and Challenges in Deep Blue Emitting Quasi‐2D and Nanocrystalline Perovskite LEDs

Advanced Materials, EarlyView.
In this review, the recent development of deep‐blue (≤465 nm) perovskite light‐emitting diodes (PeLEDs) are summarized, using different perovskite nanomaterials, including nanocrystals (NCs), quantum dots (QDs), nanoplatelets (NPLs), quasi‐2D thin film, 3D bulk thin film, as well as lead‐free perovskite nanomaterials.
Pui Kei Ko, Jianchao Ge, Pengbo Ding, Dezhang Chen, Hoi Lam Tammy Tsang, Nitish Kumar, Jonathan E. Halpert   +6 more
wiley   +1 more source

Materials Advances in Devices for Heart Disease Interventions

Advanced Materials, EarlyView.
This review examines the crucial role of materials in heart disease interventions, focusing on strategies for monitoring, managing, and repairing heart conditions. It discusses the material requirements for medical devices, highlighting recent innovations and their impact on cardiovascular health.
Gagan K. Jalandhra, Lauryn Srethbhakdi, James Davies, Chi Cong Nguyen, Phuoc Thien Phan, Zachary Och, Aditya Ashok, Khoon S. Lim, Hoang‐Phuong Phan, Thanh Nho Do, Nigel H. Lovell, Jelena Rnjak‐Kovacina   +11 more
wiley   +1 more source

Intravenous antiplatelet therapies (glycoprotein IIb/IIIa receptor inhibitors and cangrelor) in percutaneous coronary intervention: from pharmacology to indications for clinical use

Therapeutic Advances in Cardiovascular Disease, 2019
Oral antiplatelet drugs are crucially important for patients with acute coronary syndrome or stable coronary artery disease undergoing percutaneous coronary intervention (PCI).
Davide Capodanno, Rocco P. Milluzzo, Dominick J. Angiolillo   +2 more
doaj   +1 more source

Understanding Multi‐Stage Charge Storage on Nanoporous Carbons in Zn‐Ion Hybrid Capacitors

Advanced Materials, EarlyView.
Porous carbons with tunable pore sizes are synthesized to investigate the impact of pore size on charge storage in Zn‐ion hybrid capacitors. An unusual multi‐stage charge storage mechanism is revealed, involving a transition from capacitive Zn2+ ion storage to faradaic Had adsorption on the carbon surface, providing new insights into Zn‐ion ...
Jiaxin Li, Kangkang Ge, Anastatios Orestis Grammenos, Pierre‐Louis Taberna, Patrice Simon, Markus Antonietti, Mateusz Odziomek   +6 more
wiley   +1 more source

Design of HIV-1-PR inhibitors which do not create resistance: blocking the folding of single monomers [PDF]

arXiv, 2005
One of the main problems of drug design is that of optimizing the drug--target interaction. In the case in which the target is a viral protein displaying a high mutation rate, a second problem arises, namely the eventual development of resistance. We wish to suggest a scheme for the design of non--conventional drugs which do not face any of these ...
arxiv  

Electron Extraction Optimization for Carbon‐Based Hole‐Conductor‐Free Perovskite Photovoltaics With Record 1.41 V VOC

Advanced Materials, EarlyView.
A gradient electron energy level strategy is constructed to reduce voltage losses in planar HTL‐free CsPbI2Br C‐PSCs. This electron extraction optimization enables rapid photogenerated electron extraction and carrier separation, thereby suppressing recombination at the back contact. The resulting PSCs deliver a record VOC of 1.41 V, a high PCE of 17.42%
Zhiqi Li, Xiyun Xie, Zhenhai Ai, Yu Han, Tao Zhu, Ruijie Ma, Heng Liu, Xinhui Lu, Qi Wei, Mingjie Li, Junyan Xiao, Kuan Liu, Zhiwei Ren, Gang Li   +13 more
wiley   +1 more source

TKI-Related Platelet Dysfunction Does Not Correlate With Bleeding in Patients With Chronic Phase-Chronic Myeloid Leukemia With Complete Hematological Response

Clinical and Applied Thrombosis/Hemostasis, 2019
Bleeding has been reported in patients with chronic myeloid leukemia (CML) using tyrosine kinase inhibitors (TKIs). In this study, we aimed to evaluate platelet functions and associated bleeding symptoms in patients with CML using TKIs.
Yigit Sener MD, Mufide Okay MD, Seda Aydin MD, Yahya Buyukasik MD, Filiz Akbiyik MD, Zeliha Gunnur Dikmen MD   +5 more
doaj   +1 more source

Modeling Platelet P2Y$_1$/$_{12}$ Pathway to Integrin Activation [PDF]

arXiv
Through experimental studies, many details of the pathway of integrin $\alpha_{\rm IIb}\beta_3$ activation by ADP during the platelet aggregation process have been mapped out. ADP binds to two separate G protein coupled receptors on platelet surfaces, leading to alterations in the regulation of the small GTPase RAP1.
arxiv  

Interaction of Oligonucleotides with Gold Nanoparticles: Factors Beyond Electrostatic and Van‐Der Waals Forces

Advanced Materials Interfaces, EarlyView.
The formation of stable clusters of gold nanoparticles with oligonucleotides at different solution conditions is explored. DNA base homogeneity and strand directionality influence the binding with gold nanoparticles leading to interesting clustering behavior that can be relevant for SERS applications.
Shaila Thakur, Nicola Cavallini, Debora Ferrari, Laura Fabris   +3 more
wiley   +1 more source