Results 101 to 110 of about 54,964 (304)
Study of Factors to Increase the Usage Rate of Generic Drugs in Platelet Aggregation Inhibitors. [PDF]
Inquiry, 2023 Suzuki T +9 more
europepmc +1 more source
Intracerebral Hemorrhage Induces Monocyte TNF Signaling in Patients That Is Suppressed by BAF312
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Intracerebral hemorrhage (ICH) causes high morbidity and mortality, with neurotoxic inflammation driven by infiltrating monocytes. This study is an in‐depth longitudinal examination of the immune response during the first week of ICH in the presence and absence of the immunomodulatory drug BAF312 (Siponimod).
Jonathan Howard DeLong +10 more
wiley +1 more source
Inhibitors of phosphatidylinositide 3-kinase: effects on reactive oxygen species and platelet aggregation [PDF]
, 2014 Phosphoinositide 3-kinase (PI 3-kinase) exists in cells as a family of isoforms. The enzymes are important regulators of fundamental metabolic processes, such as energy utilization, growth, cell proliferation and survival.
Muhammad Ahmed Mesaik +7 more
core
Investigation of shear dependent platelet aggregation [PDF]
, 2017 This research investigates the shear rate dependence of platelet aggregation geometry and the characteristics of flow around fixed platelet aggregations to understand the role of fluid mechanics in cell adhesion and platelet aggregation mechanisms.
Tolouei, Elham (3754810)
core +1 more source
Drug Design, Development and Therapy, 2015 Nadia Khan,1,2 Ahsana Dar Farooq,1 Bassem Sadek21Dr Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, Pakistan; 2Department of Pharmacology and ...
Khan N, Farooq AD, Sadek B
doaj
Aluminum induces lipid peroxidation and aggregation of human blood platelets
Brazilian Journal of Medical and Biological Research, 1997 Aluminum (Al3+) intoxication is thought to play a major role in the development of Alzheimer's disease and in certain pathologic manifestations arising from long-term hemodialysis.
T.J.C. Neiva +4 more
doaj +1 more source
Rheumatologic Manifestations of Patients With Type B Insulin Resistance
Arthritis Care &Research, EarlyView.Objective The objectives of this study were to identify laboratory and clinical features associated with type B insulin resistance (TBIR), a rare condition caused by autoantibodies that inhibit the insulin receptor, most frequently occurring in the setting of systemic lupus erythematosus (SLE), and to increase awareness of this rare, life‐threatening ...
S. Amara Ogbonnaya +4 more
wiley +1 more source
Synthesis of Coumarin Derivatives as Inhibitors of Platelet Aggregation [PDF]
, 2008 In a search for the inhibitors of platelet aggregation, certain coumarin derivatives were synthesized and evaluated for antiplatelet activity against thrombin (Thr)-, arachidonic acid (AA)-, collagen (Col), and platelet- activating-factor (PAF)-induced
CHEN, YEH-LONG;WANG, TAI-CHI;LEE, KUAN-HAN;TZENG, CHERNG-CHYI;CHANG, YA- LING;TENG, CHE-MING +1 more
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Differences and similarities in the effects of ibrutinib and acalabrutinib on platelet functions
Haematologica, 2019 While efficient at treating B-cell malignancies, Bruton tyrosine kinase (BTK) inhibitors are consistently reported to increase the risk of bleeding. Analyzing platelet aggregation response to collagen in platelet-rich plasma allowed us to identify two ...
Jennifer Series +6 more
doaj +1 more source
Arthritis Care &Research, EarlyView.People with systemic autoimmune and rheumatic diseases (SARDs) are at higher risk than the general population of experiencing adverse pregnancy and perinatal outcomes such as preeclampsia, intrauterine growth restriction, and maternal and/or fetal death.
Mehret Birru Talabi, Sonya Borrero
wiley +1 more source