Results 131 to 140 of about 237,328 (413)

cAMP- and cGMP-elevating agents inhibit GPIbα-mediated aggregation but not GPIbα-stimulated Syk activation in human platelets

open access: yesCell Communication and Signaling, 2019
Background The glycoprotein (GP) Ib-IX-V complex is a unique platelet plasma membrane receptor, which is essential for platelet adhesion and thrombus formation.
Stephanie Makhoul   +6 more
doaj   +1 more source

Effective Interaction of Charged Platelets in Aqueous Solution: Investigations of Colloid Laponite Suspensions by Static Light Scattering and Small-Angle X-Ray Scattering [PDF]

open access: yes, 2005
We study dilute aqueous solutions of charged disk-like mineral particles (Laponite) by a combination of static light scattering (SLS) and small-angle x-ray scattering (SAXS). Laponite solutions are known to form gels above a certain critical concentration that must be described as non-equilibrium states.
arxiv   +1 more source

Effects of Tipranavir, Darunavir, and Ritonavir on Platelet Function, Coagulation, and Fibrinolysis in Healthy Volunteers [PDF]

open access: yes
The use of HIV protease inhibitors (PIs) as part of antiretroviral therapy in the treatment of HIV-1 infection may be associated with an increased risk of bleeding. This prospective, randomized, open-label trial in healthy volunteers compared the effects
Aslanyan, Stella   +5 more
core   +2 more sources

Antithrombotic therapy after myocardial reperfusion in acute myocardial infarction [PDF]

open access: yes, 1988
The problem of post-thrombolytic reocclusion can be approached in several ways. 1) Better thrombolytic agents with longer duration of effects and more powerful properties aimed at enhanced clot lysis and anticoagulation are under study.
Badimon, Lina   +3 more
core   +1 more source

Characterization and cDNA Cloning of a Platelet Aggregation Inhibitor

open access: yesMolecules and Cells, 2000
A novel platelet aggregation inhibitor, sal-C, was purified to homogeneity from the venom of Korean snake (Agkistrodon halys brevicaudus). Several lines of experimental evidence clearly indicated that sal-C inhibits not only the collagen-induced platelet aggregation, but also the aggregation mediated by the cell surface glycoprotein IIb-IIIa (GP IIb ...
Y S, Koh, D S, Kim
openaire   +2 more sources

3D Nano‐architected Polymer Shell Enables Reconfigurable Stabilized Blue Phase Soft Crystals

open access: yesAdvanced Functional Materials, EarlyView.
Spherical polymer shells featuring nanostructure of blue phase (BP) disclinations form via in situ photo‐polymerization within BP liquid crystals, providing controlled anchoring for BP nucleation and growth at room temperature and beyond. This architected confinement enhances BP thermal stability over a broad temperature range while enabling dynamic ...
Sepideh Norouzi   +8 more
wiley   +1 more source

Aspirin-dependent effects on purinergic P2Y1 receptor express [PDF]

open access: yes, 2019
Chronic treatment with aspirin in healthy volunteers (HVs) is associated with recovery of adenosine diphosphate (ADP)-induced platelet activation. The purinergic P2Y1 receptor exerts its effects via a Gq-protein, which is the same biochemical pathway ...
Alemanno, Laura   +8 more
core   +1 more source

Magnetically Guided Mechanoactive Mineralization Scaffolds for Enhanced Bone Regeneration

open access: yesAdvanced Functional Materials, EarlyView.
A 3D‐printed ‘rebar‐concrete’ inspired scaffold (PGS‐P@MGel) synergizes spontaneous biomineralization with magneto‐mechanical stimulation through PDA@Fe3O4‐embedded hydrogel. This dual biointerface activates Piezo1/β‐catenin/YAP mechanotransduction axis, enhancing BMSCs osteogenesis and angiogenesis simultaneously.
Xuran Guo   +10 more
wiley   +1 more source

Impact of acute exacerbations on platelet reactivity in chronic obstructive pulmonary disease patients

open access: yesInternational Journal of COPD, 2017
Mariana Muñoz-Esquerre,1 José Luis Ferreiro,2 Daniel Huertas,1,3 Ana Lucrecia Marcano,2 Marta López-Sánchez,1 Gerard Roura,2 Joan Antoni Gómez-Hospital,2 Jordi Dorca,1 Angel Cequier,2 Salud Santos1,3 1Department of ...
Muñoz-Esquerre M   +9 more
doaj  

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