Results 301 to 310 of about 222,697 (389)

A narrow therapeutic window of platelet P2Y₁₂ reactivity in high-risk Chinese percutaneous coronary intervention patients. [PDF]

PeerJ
Gong L, Liu Y, Li J, Tan S, Guo C, Wang Z, Song H, Kuang Y, Cao Y, Yang G.   +9 more
europepmc   +1 more source

Biomimetic Nanomedicine for Senescence‐Modulated Immune Activation Enhances Immunotherapy Efficacy in Hepatocellular Carcinoma

Advanced Science, EarlyView.
A multifunctional mPDZM nanoplatform is developed in this study. mPDZM integrates chemotherapy‐induced senescence, selective senolysis, and STING‐mediated immune activation. mPDZM effectively clears senescent tumor cells, remodels the tumor immune microenvironment, and enhances antitumor T‐cell responses.
Shiji Fang, Liyun Zheng, Bin Lin, Jiale Chen, Dehai Hou, Yiming Ding, Mengzhu Han, Pan Qin, Mengyuan Wang, Xiaoju Guo, Yeyu Zhang, Gaofeng Shu, Fazong Wu, Jianfei Tu, Minjiang Chen, Zhongwei Zhao, Zhuang Liu, Jiansong Ji   +17 more
wiley   +1 more source

Mevalonic acid exerts procoagulant effect by potentiating factor Xa. [PDF]

Nat Prod Bioprospect
Niu L, Liu C, Wang S, Yin Q, Lin S, Yan M, Li W, Yin Y, Wang W, Yu W, Tang X, Xue M, Wang Y.   +12 more
europepmc   +1 more source

Rod‐Shaped Nanotherapeutics Alleviate Rheumatoid Arthritis by Precisely Disrupting Platelet‐Mediated Pathological Crosstalk via a Morphology‐Dependent Manner

Advanced Science, EarlyView.
Owing to the margination effect, rod‐shaped nanoparticles exhibit markedly enhanced co‐localization with endothelial‐adherent platelets (PLTs) under dynamic blood flow. When internalized by PLTs, rod‐shaped PNR@Res inhibit FAK and PI3K/AKT signaling in a morphology‐dependent manner, thereby disrupting their pathological crosstalk with various ...
Bin Zhang, Yuanyi Hua, Xin Wen, Zhumei Liao, Jianheng Ren, Yajun Weng, Qin Wang   +6 more
wiley   +1 more source

A Critical Review of the Molecular and Clinical Effects of Cilostazol After Percutaneous Coronary Intervention. [PDF]

J Cardiovasc Dev Dis
Ferrari R, Perrone Filardi P.
europepmc   +1 more source

Artemisinin inhibits collagen-induced human platelets aggregation through regulation of PI3K/Akt and MAPK pathway

Chang-Eun Park, Dong‐Ha Lee
openalex   +2 more sources

F13A1‐Mediated Macrophage Activation Promotes MASH Progression via the PKM2/HIF1A Pathway

Advanced Science, EarlyView.
In fatty liver disease, hepatocytes exposed to palmitate release S1P, which activates calcium signaling in macrophages. Elevated calcium enhances the activity of F13A1, driving PKM2 dimerization. The PKM2 dimers cause Warburg effect, translocate to the nucleus, cooperate with HIF1A, and upregulate IL1B expression, ultimately promoting classical ...
Qianrang Lu, Meiching Ong, Xuewen Yi, Muqiong Xing, Xinyao Tian, Ke Zhang, Ling Lu, Hao Wang, Xiaohan Lin, Jun Fang, Aibo Mu, Jiaying Cao, Jingyu Jiang, Feng Gao, Hongjun Li, Baohong Wang, Qi Ling   +16 more
wiley   +1 more source

Analysis of drug-drug interactions in spontaneous adverse drug reaction reports from EudraVigilance focusing on psychiatric drugs and somatic medication. [PDF]

BMC Psychiatry
Dubrall D, Weber R, Böhme M, Schmid M, Sachs B, Scholl C.   +5 more
europepmc   +1 more source

Where Can Aluminum Go When Batteries Die?

Advanced Science, EarlyView.
Battery‐derived aluminum is transformed from contaminated waste into an alloying resource for high‐performance Fe‐based alloys. Through controlled Al content and processing, dual‐phase austenite/ferrite microstructures with TRIP‐like behavior are achieved.
Raymond Kwesi Nutor, Waleed Mohammed, Se‐Ho Kim, Baptiste Gault   +3 more
wiley   +1 more source

Inclisiran in Dyslipidemia with High Residual Platelet Reactivity. [PDF]

Diseases
Kapsultanova D, Zhangelova S, Nurmukhammad F, Makasheva Z, Sakhov O, Galkina T, Rustamova F, Akhmentayeva D, Aubakirova B.   +8 more
europepmc   +1 more source