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Platelet Aggregation Inhibitors
Encyclopedia of Molecular Pharmacology, 2021semanticscholar +1 more source
ChemInform Abstract: SUBSTITUTED 3,4‐PENTADIENYLDIAMINES AS INHIBITORS OF PLATELET AGGREGATION
Chemischer Informationsdienst, 1973AbstractKondensation der Allenaldehyde (III) mit den Diaminen (IV) und nachfolgende Reduktion der Schiffschen‐Basen (V) in situ mit Kaliumborhydrid liefern die Pentadienyldiamine (VI), die auf ihre Wirkung als Hemmstoffe der Blutblättchen‐Aggregation untersucht werden.
Thomas R. Blohm +3 more
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2,3-Diphosphoglycerate: A Physiological Inhibitor of Platelet Aggregation
Science, 19752,3-Diphosphoglycerate (2,3-DPG) may inhibit the platelet release reaction and the irreversible aggregation of human blood platelets induced by adenosine diphosphate, epinephrine, or norepinephrine. The effects of 2,3-DPG on platelet aggregation were more pronounced in cases with low hematocrit (< 30 percent).
Sotirios G. Iatridis +3 more
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PLATELET AGGREGATION INHIBITOR IN GARLIC [PDF]
Susumu Oshiba +2 more
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Platelet phosphorylase activity in the presence of activators and inhibitors of aggregation
Biochemical and Biophysical Research Communications, 1970Phosphorylase activity in suspension of human platelets was assayed prior to and following addition of thrombin and epinephrine which aggregate platelets prostaglandin E1 and E2 and adenosine cyclic 35 monophosphate which inhibit aggregation or sodium fluoride and isoproterenol which alter adenine nucleotide metabolism.
Sidney M. Wolfe +2 more
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Chapter 7. Platelet Aggregation Inhibitors
1971Publisher Summary This chapter presents an overview of the platelet aggregation inhibitors. The therapeutic approach to thromboembolic disease is based on the inhibition of platelet aggregation. The use of fibrinolytic agents for the dissolution of thrombi and the prophylactic use of anticoagulants for their prevention has been known for some time ...
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New Platelet Aggregation Inhibitors [PDF]
R. Verhaeghe, J. Vermylen
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Design, synthesis and QSAR study of arylidene indoles as anti-platelet aggregation inhibitors
Medicinal Chemistry Research, 2015S. S. Mirfazli +5 more
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