The Rise of Mechanobiology for Advanced Cell Engineering and Manufacturing
With the growing demand for cell‐based therapies, efficient cellular engineering is crucial. This review calls for greater recognition of mechanobiology principles applied through advanced biomaterial designs, mechanical confinement, and highlights recent advances using micro/nanotechnologies to enhance cell manufacturing.
Huan Ting Ong+8 more
wiley +1 more source
Platelet-collagen adhesion: inhibition by a monoclonal antibody that binds glycoprotein IIb. [PDF]
P. J. Shadle+3 more
openalex +1 more source
Designing the Next Generation of Biomaterials through Nanoengineering
Nanoengineering enables precise control over biomaterial interactions with living systems by tuning surface energy, defects, porosity, and crystallinity. This review highlights how these nanoscale design parameters drive advances in regenerative medicine, drug delivery, bioprinting, biosensing, and bioimaging, while outlining key translational ...
Ryan Davis Jr.+3 more
wiley +1 more source
Biomimetic Cell Membrane‐Coated Scaffolds for Enhanced Tissue Regeneration
This review examines the development and use of cell membrane‐coated scaffolds in tissue engineering. Bioinspired phospholipid and glycocalyx coatings enhance anti‐fouling, anti‐thrombogenic, and selective molecular recognition properties. Native cell membrane coatings further support cell‐specific interactions, immune modulation, and reduced bacterial
Carmen Alvarez‐Lorenzo+5 more
wiley +1 more source
Antithrombotic effect of a monoclonal antibody to the platelet glycoprotein IIb/IIIa receptor in an experimental animal model [PDF]
BS Coller+3 more
openalex +1 more source
Nanostructured Protein Surfaces Inspired by Spider Silk
Harnessing recombinant spider silk technology, bioengineered spidroin variants enable the creation of functionalized nanostructured coatings with tunable affinity for specific targets, supporting a broad range of applications ‐ from antifouling surfaces and targeted drug delivery to advanced cell therapies and precision bio‐patterning via lithography ...
Martin Humenik, Thomas Scheibel
wiley +1 more source
Two monoclonal antiplatelet antibodies as markers of human megakaryocyte maturation: immunofluorescent staining and platelet peroxidase detection in megakaryocyte colonies and in in vivo cells from normal and leukemic patients [PDF]
William Vainchenker+6 more
openalex +1 more source
An engineered in vitro platform mimicking stent strut cross‐sectional shapes reveals how geometry influences cell behavior. Sharp‐cornered geometries promote cell proliferation and matrix alignment, while rounded shapes reduce these effects. The findings align with clinical outcomes and suggest intracellular tension as a key driver, offering a ...
Emmie J.D. Schoutens+5 more
wiley +1 more source
A review of immune thrombocytopenic purpura: focus on the novel thrombopoietin agonists
Meaghan Khan, Joseph MikhaelDivision of Hematology – Oncology, Scottsdale, AZ, USAAbstract: Immune thrombocytopenic purpura (ITP) is an autoimmune disorder that is characterized by antibody-mediated platelet destruction and decreased platelet ...
Meaghan Khan, Joseph Mikhael
doaj
Inhibition of autoantibody binding to platelet glycoprotein IIb/IIIa by anti-idiotypic antibodies in intravenous gammaglobulin [PDF]
Peter Berchtold+3 more
openalex +1 more source