Results 161 to 170 of about 2,173,038 (398)

Wedelolactone, a Novel TLR2 Agonist, Promotes Neutrophil Differentiation and Ameliorates Neutropenia: A Multi‐Omics Approach to Unravel the Mechanism

Advanced Science, EarlyView.
Wedelolactone (WED), a natural TLR2 agonist, promotes neutrophil differentiation and enhances bactericidal function, offering a potential therapeutic strategy for neutropenia. Using a multi‐omics approach, this study reveals that WED activates the TLR2/MEK/ERK pathway, upregulating key transcription factors (PU.1, CEBPβ) to drive neutrophil development.
Long Wang, Zhichao Li, Tianci Hu, Qinyao Li, Linwei Zhang, Xinyue Mei, Xiao Qi, Sheng Liu, Weijie Kong, Jiesi Luo, Anguo Wu, Feihong Huang, Sirui Li, Shuang Dai, Chunxiang Zhang, Rong Li, Jianming Wu   +16 more
wiley   +1 more source

Development of detection kit for anti-platelet antibodies in patients with thrombocytopenia by modified SPRCA

Journal of Associated Medical Sciences, 2008
Detection of anti-platelet alloantibodies in serum of patients with thrombocytopenia is important for helps in diagnosis and investigation as well as specific treatment. Since, platelets provide both common and platelet specific antigens which can induce
Witoon Sriwichai, Jaturaporn Pornsinlapatip, Preeyanat Vongchan   +2 more
doaj  

In vitro detection of platelet antibody in patients with idiopathic thrombocytopenic purpura and systemic lupus erythematosus.

Blood, 1969
S. Karpatkin, G. Siskind
semanticscholar   +1 more source

Real‐world performance of a clinical droplet digital polymerase chain reaction assay for non‐invasive foetal blood group and platelet antigen genotyping of alloimmunized pregnant women with antibodies directed against RhD, RhE, Rhc, RhC, K1, HPA‐1a or HPA‐5b: A 1‐year experience [PDF]

Camilla Calandrini, O. J. H. M. Verhagen, Ahmed Tissoudali, Christa Homburg, Jessica Vessies, M. Brussee, Eric H van Beers, C. Ellen van der Schoot, Masja de Haas   +8 more
openalex   +1 more source

Cinnamic‐Hydroxamic‐Acid Derivatives Exhibit Antibiotic, Anti‐Biofilm, and Supercoiling Relaxation Properties by Targeting Bacterial Nucleoid‐Associated Protein HU

Advanced Science, EarlyView.
Cinnamic‐hydroxamic‐acid derivatives (CHADs) are identified as novel inhibitors of the bacterial nucleoid‐associated protein HU, exhibiting potent antibacterial, anti‐biofilm (both inhibition and eradication), and DNA relaxation (anti‐supercoiling) activities. Moreover, CHADs demonstrate strong synergistic effects with multiple antibiotics.
Huan Chen, Yingqi Xu, Zhaoping Xiong, Hongliang Wang, Xin Wang, Yue Kang, Zhonglin Wang, Xiaoyan Zeng, Yahui Liu, Yehuan Zheng, Wei Chen, Mengzhe Li, Zhenyue Hu, Chi Xu, Yue Wu, Yawen Wang, Zuyi Yuan, Shuai Yuan, Huadong Liu, Steve Matthews, Nan Qiao, Yan Li, Bing Liu   +22 more
wiley   +1 more source

A monoclonal anti-human platelet antibody: a new platelet aggregating substance.

Blood, 1985
M. Higashihara, H. Maeda, Y. Shibata, S. Kume, T. Ōhashi   +4 more
semanticscholar   +1 more source

A murine antiglycoprotein Ib complex monoclonal antibody, SZ 2, inhibits platelet aggregation induced by both ristocetin and collagen [PDF]

, 1987
CG Ruan, XP Du, XD Xi, PA Castaldi, MC Berndt   +4 more
openalex   +1 more source

Human Atlas of Tooth Decay Progression: Identification of Cellular Mechanisms Driving the Switch from Dental Pulp Repair Toward Irreversible Pulpitis

Advanced Science, EarlyView.
Tooth decay progression transforms the dental pulp response from repair to fibrosis. At early stages, stromal cells reprogram to repair the extra cellular matrix (ECM), blood vessels, and nerves, remodel and grow, keeping repair possible. In advanced decay, hypoxia, and vessel regression, in complement with an immune switch, fuel nerve degeneration and
Hoang Thai Ha, Sofya Kosmynina, Amandine Verocq, Keremsah Ozen, Ines Tekia, Hugo Bussy, Marie Ramirez, Dima Sabbah, Chloe Goemans, Valerie Vandenbempt, Esteban N. Gurzov, Sumeet Pal Singh, Nicolas Baeyens   +12 more
wiley   +1 more source

Clinical Applications of Platelet Antibody and Antigen Testing

, 2011
Andrew J. Lochowicz, B. Curtis
semanticscholar   +1 more source

Simultaneous flow cytometric detection of antibodies against platelets, granulocytes and lymphocytes

, 1991
Kees Sintnicolaas, W. de Vries, Reinier van der Linden, Jan W. Gratama, R. L. H. Bolhuis   +4 more
openalex   +2 more sources