Results 241 to 250 of about 2,173,038 (398)

Limitations of rituximab in treating primary immune thrombocytopenia and the therapeutic potentials of alternatives. [PDF]

Curr Opin Hematol
Pan L, Zhu J.
europepmc   +1 more source

Complement-induced procoagulant platelets in patients with antiphospholipid antibodies [PDF]

Paresh Kulkarni, Maierdan Palihati, Anne Hubben, Michael Cole, Bhagwati Joshi, Dana Angelini, Sandra Mazzoni, Shruti Chaturvedi, Robert Brodsky, Keith McCrae   +9 more
openalex   +1 more source

A Novel Flow Cytometric Method for the Simultaneous Detection of Antibodies Against Platelet, Lymphocyte, And Neutrophil [PDF]

, 2016
Myung Chul Suh, Jang Soo Suh, Dong Il Won   +2 more
openalex   +1 more source

Label‐Free Leukocyte Biophysical Profiling Using Impedance‐Deformability Cytometry for Rapid Cardiovascular Risk Stratification

Advanced Science, EarlyView.
This study presents an impedance‐based single‐cell profiling platform that quantifies the electrical and mechanical properties of neutrophils across in vitro, in vivo, and clinical samples. The approach reveals distinct biophysical alterations associated with type 2 diabetes (T2DM) and cardiovascular complications, suggesting its potential utility for ...
Linwei He, Hui Min Tay, Feng Chen, Hong Sheng Cheng, Liang De Wang, Qiqi Nam, Arunachalam Thannirmalai, Lingyan Gong, Aram J. Chung, Nguan Soon Tan, King Ho Holden Li, Rinkoo Dalan, Siu Ling Wong, Han Wei Hou   +13 more
wiley   +1 more source

Platelet aging and desialylation increase apoptotic priming and BCL-X_L dependence. [PDF]

Cell Death Dis
Grozovsky R, Fraser CS, Qin X, Spetz J, Sarosiek KA.   +4 more
europepmc   +1 more source

Antibodies to Platelet Factor 4–Heparin Complex and Outcome in Hemodialysis Patients with Diabetes [PDF]

, 2010
Vera Krane, Mario Berger, Jürgen Lilienthal, Karl Winkler, C. M. Schambeck, Christoph Wanner   +5 more
openalex   +1 more source

Boron Nitride Nanomaterials Trigger Immunomodulatory Effects in Human Broncho‐Epithelial Cells by Modulating Eicosanoid Lipid Signaling

Advanced Science, EarlyView.
This study demonstrates that BNNT exposure disrupts lipid homeostasis in bronchial epithelial cell cultures and activates eicosanoid lipid biosynthesis, producing inflammatory lipid mediators like leukotrienes. These effects are more pronounced in asthmatic cell cultures compared to healthy ones.
Govind Gupta, Jonas Bossart, Sènan Mickael D'Almeida, Luis Augusto Visani de Luna, Christoph Schwärzler, Tingting Fu, Vanesa Ayala‐Nunez, Alexander Gogos, Marija Buljan, Vera M Kissling, Emmanuel Flahaut, Miguel Garcia, Cyrill Bussy, Peter Wick, Tina Buerki‐Thurnherr   +14 more
wiley   +1 more source

USP35 Acts as a Deubiquitinating Enzyme for ID3 to Promote Immune Escape in Colorectal Cancer

Advanced Science, EarlyView.
USP35 stabilizes ID3 expression by deubiquitinating the K2/K30 site, thereby upregulating PD‐L1 and promoting immune escape in colorectal cancer. IU1, an inhibitor of USP35 enzyme activity, has been shown to inhibit USP35, thereby accelerating ID3 degradation, enhancing CD8+ T cell killing, and reversing the immunosuppressive microenvironment ...
Wenxin Chen, Ling Wang, Hongmei Fan, Lisheng Li, Lingyu Zhang, Ruoxin Li, Fang Liu, Fuli Wen, Yunbin Ye, Chuanzhong Huang   +9 more
wiley   +1 more source

Addition of ADAMTS13 testing to cryptogenic stroke evaluation: index case and single-center screening initial experience. [PDF]

Blood Adv
Boothby A, Ruiz Lopez JN, Hegerova L, Manogna D, Chintapatla R, Harris S, Teramura G, Tirschwell D, Taylor B, Keel S.   +9 more
europepmc   +1 more source

Core Fucosylation Represses SMURF1‐Dependent Degradation of CD47 to Promote Tumor Immune Evasion

Advanced Science, EarlyView.
FUT8‐mediated core fucosylation of CD47 at N111 blocks SMURF1 binding and reduces CD47 ubiquitination and degradation. Blocking N111 glycosylation reduces CD47 expression and promotes macrophage phagocytosis of tumor cells. Furthermore, ablating CD47 core fucosylation boosts CD103+ dendritic cells (DCs) infiltration, increases natural killer (NK) cell ...
Yuting Cao, Siyuan Chai, Mingyang Li, Xiaoming Chen, Jiating Hu, Bingyi Lin, Liming Wu, Wen Yi, Qiang Zhu   +8 more
wiley   +1 more source