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Platelet Antibodies in Patients With Migraine
Headache: The Journal of Head and Face Pain, 1998The reported decrease of platelet serotonin receptors in patients with migraine could be due to an autoimmune reaction. We, therefore, examined sera from 42 migraineurs without aura, 26 migraineurs with aura, and 107 headache‐free blood donors for platelet‐reactive antibodies using the platelet adhesion immunofluorescence test, the NIH ...
M, Schabet +3 more
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Platelet Antibodies in Thrombocytopenic Patients
British Journal of Haematology, 1977Platelet antibodies either bound to the surface of platelets or free in the serum were sought in patients who had low platelet counts for a variety of reasons. They were detected by finding excess IgG on the surface of washed platelets either directly or after incubation of the serum with normal platelets.
U M, Hegde +2 more
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Clinics in Laboratory Medicine, 1996
The proper diagnosis of patients with immune-mediated thrombocytopenias can be accomplished by using the advances made in the field of platelet serology. These techniques range from solid phase red cell adherence to sequencing platelet antigen amino acids by polymerase chain reaction.
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The proper diagnosis of patients with immune-mediated thrombocytopenias can be accomplished by using the advances made in the field of platelet serology. These techniques range from solid phase red cell adherence to sequencing platelet antigen amino acids by polymerase chain reaction.
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Human Platelet Activating Antibodies
Seminars in Thrombosis and Hemostasis, 1992Platelet antibodies identified in the plasma of three multiply transfused patients and a woman who had delivered a baby with neonatal alloimmune thrombocytopenia were investigated for their platelet activating properties. Three patients possessed multispecific HLA antibodies reactive with 90 to 100% of the cells on a lymphocytotoxic panel.
D J, Christie, C D, Swinehart
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Laboratory testing for platelet antibodies
American Journal of Hematology, 2013Laboratory testing for immune‐mediated thrombocytopenias involves identification and classification of antibodies present in patient sera or attached to patient platelets. This article summarizes the available types of platelet antibody testing and applications in disorders such as neonatal alloimmune thrombocytopenia, post‐transfusion purpura ...
Nahla M, Heikal, Kristi J, Smock
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Platelet antibodies in immune thrombocytopenia
Blood Reviews, 1992Several tests to detect antibodies to platelets in patients with immune thrombocytopenia have been developed over the 40 years since it was first noted that this disorder was mediated by antiplatelet factors. Early tests were crude and not reproducible. A major landmark was the quantitation of IgG immunoglobulin on platelet membrane and the observation
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Studies on Platelet Antibodies in Man
Vox Sanguinis, 1961SummaryThree serological methods, the agglutination test, the anti‐human globulin consumption test and the complement fixation test for the detection of platelet antibodies are described and the results given. Special attention is directed to some factors concerning the anti‐human globulin consumption test.
W M, va de WIEL +2 more
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Immune Platelet Iso-Antibodies
Vox Sanguinis, 1960Summary A technique is described in detail [12] for detecting serological factors capable of agglutinating platelets at 37°C. It consists of a modification of the agglutination technique described by Dausset and Malinvaud [9] in which an agitator was used. The modification consists of heating the platelets to 56°C.
J, DAUSSET, M, COLIN, J, COLOMBANI
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Transfusion, 2010
BACKGROUND: Glycoprotein (GP)‐specific platelet (PLT) antibodies can cause allo‐ or autoimmune thrombocytopenia. Their detection is of high diagnostic value. The simultaneous analysis of specific PLT antibodies (SASPA) assay is based on simultaneous detection of various PLT‐specific antibodies by flow cytometry and has entered routine use in our ...
Xuan Duc, Nguyen +4 more
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BACKGROUND: Glycoprotein (GP)‐specific platelet (PLT) antibodies can cause allo‐ or autoimmune thrombocytopenia. Their detection is of high diagnostic value. The simultaneous analysis of specific PLT antibodies (SASPA) assay is based on simultaneous detection of various PLT‐specific antibodies by flow cytometry and has entered routine use in our ...
Xuan Duc, Nguyen +4 more
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Identification and Significance of Platelet Antibodies
New England Journal of Medicine, 1956BLEEDING tendencies secondary to thrombopenia are of increasing frequency in medical, surgical and obstetric disorders. This has been attributed to diverse causes: chemotherapeutic agents1 , 2; insecticides3; increased incidence of leukemia4; radioisotopes; cytotoxic agents in industry5; complete blood replacement by transfusion during pulmonary or ...
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