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Low molecular weight heparin-induced thrombocytopenia management during hemodialysis and cardiac surgery: a case report and literature review. [PDF]
Takada S, Suzuki S, Tamura T.
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The Effect of Antihuman Platelet Antibodies on Human Platelets [PDF]
The influence of an heterologous antihuman platelet serum (AS) was examined an immunological approach to investigate platelet function, as induces aggregation and release from platelets in citrate plasma. Neither thrombin nor complement were requirements, and inhibitors of ADP-(adenosine) and collagen-induced (aspirin) aggregation were only slightly ...
C Jenkin+3 more
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Platelet Antibodies in Infertility Patients
Clinical Laboratory, 2021Platelet antigens can stimulate the body to produce platelet alloimmune antibodies through blood transfusion, pregnancy, and autoimmunity. In the blood of pregnant women, anti-platelet antibodies can cause embryo implantation failure, abortion, etc.
Shuyu Zhang+10 more
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Antiphospholipid antibodies and platelets
Current Rheumatology Reports, 2000The most distinguishing serologic feature of antiphospholipid syndrome (APS) is the moderate to high blood titers of antiphospholipid-binding antibodies (aPL). The pathogenic mechanisms of APS are poorly understood, but may occur as a result of the interaction between anticardiolipin antibodies (aCL), beta-2 glycoprotein-I (beta(2)GP-I) (the aCL ...
Dick L. Robbins+2 more
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Platelet Antibodies in Thrombocytopenic Patients [PDF]
Platelet antibodies either bound to the surface of platelets or free in the serum were sought in patients who had low platelet counts for a variety of reasons. They were detected by finding excess IgG on the surface of washed platelets either directly or after incubation of the serum with normal platelets.
Sheila M. Worlledge+2 more
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Platelets and Antiphospholipid Antibodies [PDF]
The involvement of platelets in the antiphospholipid syndrome is complex and the full pathogenic significance is not fully understood. The binding of aPL antibodies to the platelet membrane may result in the thrombopenia and further haemostatic activation.
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Elution of Granulocyte and Platelet Antibodies
Vox Sanguinis, 1982AbstractBy lowering the pH of the medium, allo‐ and autoantibodies bound to granulocytes and platelets could be eluted from these cells and their presence in the eluate could subsequently be detected with normal donor granulocytes and platelets, respectively, in the immunofluorescence test and/or agglutination test.
F. M. Helmerhorst+4 more
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Immune Platelet Iso-Antibodies
Vox Sanguinis, 1960Summary A technique is described in detail [12] for detecting serological factors capable of agglutinating platelets at 37°C. It consists of a modification of the agglutination technique described by Dausset and Malinvaud [9] in which an agitator was used. The modification consists of heating the platelets to 56°C.
M. Colin, J. Colombani, J. Dausset
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Laboratory testing for platelet antibodies
American Journal of Hematology, 2013Laboratory testing for immune‐mediated thrombocytopenias involves identification and classification of antibodies present in patient sera or attached to patient platelets. This article summarizes the available types of platelet antibody testing and applications in disorders such as neonatal alloimmune thrombocytopenia, post‐transfusion purpura ...
Kristi J. Smock, Nahla M. Heikal
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