Results 91 to 100 of about 3,348,298 (337)

El síndrome de la plaqueta pegajosa: serie de casos en gestantes en el hospital militar central y revisión de literatura The sticky platelet syndrome

Revista Colombiana de Obstetricia y Ginecología, 2004
El síndrome de la plaqueta pegajosa es un desorden plaquetario autosómico dominante asociado con eventos tromboembólicos arteriales y venosos.
Alvinzy II Velásquez, Vicente Carmona, Gloria Ramos   +2 more
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Novel Mutation in ITGB3: A Case Report of Glanzmann Thrombasthenia-like Syndrome Associated with Macrothrombocytopenia

Journal of Applied Hematology
Congenital thrombocytopenias are a diverse range of diseases. Of them, Glanzmann thrombasthenia is an autosomal recessive platelet aggregation disorder due to defect in the alpha IIb/beta3 integrins, coded by the ITGA2B and ITGB3 genes.
Abdulrhman Ibrahim Alathaibi, Muhammad Matloob Alam, Mohammed Kamal, Mohamed Refai, Faisal Alosaimi, Omar Allehyani, Nojood Althubaity   +6 more
doaj   +1 more source

The Rise of Mechanobiology for Advanced Cell Engineering and Manufacturing

Advanced Materials, EarlyView.
With the growing demand for cell‐based therapies, efficient cellular engineering is crucial. This review calls for greater recognition of mechanobiology principles applied through advanced biomaterial designs, mechanical confinement, and highlights recent advances using micro/nanotechnologies to enhance cell manufacturing.
Huan Ting Ong, M Sriram, Hepi Hari Susapto, Yixuan Li, Yuan Jiang, Nicolas H. Voelcker, Jennifer L. Young, Andrew W. Holle, Roey Elnathan   +8 more
wiley   +1 more source

Blood platelet research in autism spectrum disorders: In search of biomarkers

Research and Practice in Thrombosis and Haemostasis, 2019
Autism spectrum disorder (ASD) is a clinically heterogeneous neurodevelopmental disorder that is caused by gene‐environment interactions. To improve its diagnosis and treatment, numerous efforts have been undertaken to identify reliable biomarkers for ...
Manisha Padmakumar, Eveline Van Raes, Chris Van Geet, Kathleen Freson   +3 more
doaj   +1 more source

Designing the Next Generation of Biomaterials through Nanoengineering

Advanced Materials, EarlyView.
Nanoengineering enables precise control over biomaterial interactions with living systems by tuning surface energy, defects, porosity, and crystallinity. This review highlights how these nanoscale design parameters drive advances in regenerative medicine, drug delivery, bioprinting, biosensing, and bioimaging, while outlining key translational ...
Ryan Davis Jr., Ishaan Duggal, Nicholas A. Peppas, Akhilesh K. Gaharwar   +3 more
wiley   +1 more source

Introducing high-throughput sequencing into mainstream genetic diagnosis practice in inherited platelet disorders

Haematologica, 2018
Inherited platelet disorders are a heterogeneous group of rare diseases, caused by inherited defects in platelet production and/or function. Their genetic diagnosis would benefit clinical care, prognosis and preventative treatments.
José M. Bastida, María L. Lozano, Rocío Benito, Kamila Janusz, Verónica Palma-Barqueros, Mónica Del Rey, Jesús M. Hernández-Sánchez, Susana Riesco, Nuria Bermejo, Hermenegildo González-García, Agustín Rodriguez-Alén, Carlos Aguilar, Teresa Sevivas, María F. López-Fernández, Anna E. Marneth, Bert A. van der Reijden, Neil V. Morgan, Steve P. Watson, Vicente Vicente, Jesús M. Hernández-Rivas, José Rivera, José R. González-Porras   +21 more
doaj   +1 more source

Sonodynamic and Bioorthogonal Sonocatalytic Thrombotic Therapy Based on AIE Cationic Tetranuclear Ir(III) Complex Nanoplatform Guided by NIR‐Chemiluminescence Imaging

Advanced Materials, EarlyView.
AIE‐active tetranuclear Ir(III) complex Ir‐4 as a sonosensitizer/sonocatalyst is formulated into a nanoplatform with an H2S donor. Ir‐4@S‐R NPs achieves combined endogenous NIR chemiluminescence imaging, sonodynamic therapy and release of H2S in situ by a bioorthogonal sonocatalytic reaction in vivo, achieving safe thrombolysis and anti‐inflammatory ...
Zihan Wu, Liping Zhang, Ziwei Wang, Shengnan Liu, Qiaohua Zhang, Chunguang Shi, Yachao Wang, Gelin Xu, Dongxia Zhu, Martin R. Bryce, Lijie Ren, Ben Zhong Tang   +11 more
wiley   +1 more source

Preferential and sustained platelet activation in COVID-19 survivors with mental disorders

Scientific Reports
Pre-existing mental disorders are considered a risk factor for severe COVID-19 outcomes, possibly because of higher vascular burden. Moreover, an unconventional platelet activation characterizes COVID-19 and contributes to inflammatory and thrombotic ...
Norma Maugeri, Rebecca De Lorenzo, Mario Gennaro Mazza, Mariagrazia Palladini, Fabio Ciceri, Patrizia Rovere-Querini, Angelo A. Manfredi, Francesco Benedetti   +7 more
doaj   +1 more source

Thermionics in Topological Materials

Advanced Materials, EarlyView.
Thermionics is one of the fundamental energy conversion mechanisms in solid state systems. Recent development in topological materials opens new avenues in developing thermionic systems and devices. Due to the linear energy dispersion and topological protection of charge transport, these new materials are promising candidates for high efficiency ...
Sunchao Huang, Zihao Zhang, Youfeng Yang, Yuan Zheng, Abdullah Al‐Mamun, Shaomeng Wang, Zhi Li, Yubin Gong, Chao Zhang   +8 more
wiley   +1 more source

Perioperative administration of recombinant activated factor VII in a Glanzmannʼs thrombasthenia patient with platelet refractoriness: case report

Brazilian Journal of Anesthesiology, 2022
Glanzmannʼs Trombasthenia (GT) is a genetic disorder, that develops with a tendency toward bleeding and is characterized by the absence or decrease in platelet aggregation. Surgical bleeding may be difficult to control.
Flora Margarida Barra Bisinotto, Laura Bisinotto Martins, Giovanini Pires de Camargos, Marcelo de Paula Bianco   +3 more
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