Results 171 to 180 of about 3,348,298 (337)

Cellular Adaptation to Mechanical Stress Emerges via Cell Shrinkage Triggered by Nonlinear Calcium Elevation

Advanced Science, EarlyView.
Here, a decision‐making mechanism underlying mechanical adaptation is demonstrated. This study demonstrates that cellular adaptation to mechanical stress can be induced by applying low‐amplitude stretch to cells. When the stretch reaches a critical amplitude threshold, it triggers Ca2⁺‐dependent positive feedback, which induces cholesterol efflux and ...
Zhengyan Wang, Zihan Li, Lei Wang, Haitao Zhang, Xiaoshan Yang, Lili Bao, Geng Dou, Lili Ren, Yajing Fu, Lan Li, Shengkai Gong, Yang Zhou, Feng Ding, Lu Yu, Haotian Luo, Yao Liu, Fuyang Zhang, Hui Yu, Siying Liu, Xueming Liu, Fulan Wei, Shiyu Liu   +21 more
wiley   +1 more source

Thrombocytopenia: the most frequent haemostatic disorder in the ICU

Anaesthesiology Intensive Therapy, 2019
Thrombocytopenia is the most common haemostatic disorder in patients admitted to Intensive Care Units (ICUs). The mechanisms contributing to a decrease in the platelet count in critically ill patients are multifactorial, among which sepsis and trauma are
Jan Pluta, Janusz Trzebicki
doaj  

Increased bleeding and thrombosis in myeloproliferative neoplasms mediated through altered expression of inherited platelet disorder genes

, 2023
Mitchell A, Frontini M, Islam S, Sivapalaratnam S, Krishnan A.   +4 more
europepmc   +1 more source

Detecting coagulation disorders of pregnancy: bleeding time or platelet count? [PDF]

, 2001
Charles Marc Samama, L Simon
openalex   +1 more source

RUNX1, but not its familial platelet disorder mutants, synergistically activates PF4 gene expression in combination with ETS family proteins

Journal of Thrombosis and Haemostasis, 2013
Y. Okada, M. Watanabe, T. Nakai, Y. Kamikawa, M. Shimizu, Y. Fukuhara, M. Yonekura, E. Matsuura, Y. Hoshika, R. Nagai, W. Aird, T. Doi   +11 more
semanticscholar   +1 more source

Energy‐Efficient Fabrication of Biomimetic Materials for Sustainable Infrastructure Applications

Advanced Science, EarlyView.
Inspired by nacre's “brick‐and‐mortar” structure, this work develops an energy‐efficient approach that utilizes ice‐templating technology as the structure framework and carbon mineralization for rapid CaCO3 production, resulting in a strong yet tough carbon mineralized material (CMM) under mild conditions while also fixing CO2.
Jingze Chen, Zhichao Liu, Shujun Zhang, Shuguang Hu, Fazhou Wang   +4 more
wiley   +1 more source

First description of revertant mosaicism in familial platelet disorder with predisposition to acute myelogenous leukemia: correlation with the clinical phenotype. [PDF]

Haematologica, 2020
Glembotsky AC, Marin Oyarzún CP, De Luca G, Marzac C, Auger N, Goette NP, Marta RF, Raslova H, Heller PG.   +8 more
europepmc   +1 more source

Platelet spherocytosis: A new bleeding disorder [PDF]

, 2002
James G. White, Pedro A. de Alarcón
openalex   +1 more source

An Off‐the‐Shelf Artificial Blood Clot Hydrogel Neutralizing Multiple Proinflammatory Mediators for Pro‐Regenerative Periodontitis Treatment

Advanced Science, EarlyView.
CCS‐RSF@PRP hydrogel is engineered to structurally and functionally mimic the blood clot by integrating PPR, CCS, and RSF nanofibers through in situ activation of PRP. In a rat periodontitis model, CCS‐RSF@PRP hydrogel effectively promotes periodontal tissue repair, attributing to neutralizing the multiple proinflammatory mediators, thus rebuilding a ...
Yini Huangfu, Zhezhe Zhao, Xiang Liu, Jingrong Wang, Yufeng Zhang, Tingting Lan, Yonglan Wang, Chenxuan Wu, Ju Zhang, Pingsheng Huang, Chuangnian Zhang, Anjie Dong, Zujian Feng, Deling Kong, Weiwei Wang   +14 more
wiley   +1 more source

The Immune Microenvironment: New Therapeutic Implications in Organ Fibrosis

Advanced Science, EarlyView.
This review summarizes recent advances in understanding the immune microenvironment's role in fibrosis, focusing on phenotypic/functional alterations of immune cells and their dynamic interactions with other cellular constituents within tissues. The authors further explore therapeutic opportunities and challenges in targeting immune microenvironment ...
Xiangqi Chen, Chuan Wu, Fei Tang, Jingyue Zhou, Li Mo, Yanping Li, Jinhan He   +6 more
wiley   +1 more source