Results 181 to 190 of about 182,278 (349)

Diagnosis and Management of Inherited Platelet Disorders [PDF]

, 2010
C.M. Kirchmaier, Daniele Pillitteri
openalex   +1 more source

A Lung‐Immune Dual‐Humanized Mouse Using Cryopreserved Tissue Enables Infection and Immune Profiling of Human Common Cold Coronaviruses

Advanced Science, EarlyView.
Cryopreserved lung‐humanized mice overcome the dependency to fresh tissues and permit head‐to‐head profiling of all four human common cold coronaviruses versus SARS‐CoV‐2 infection; the model validates Paxlovid efficacy against HKU1 and, when coupled with human immune‐system engraftment, enables interrogation of lung‐resident human immunity and HKU1 ...
Chunyu Cheng, Jing Sun, Chun Lu, Qian Yu, Yiyun He, Bingqing Wu, Deshan Ren, Shuai Ding, Jincun Zhao, Yan Li   +9 more
wiley   +1 more source

Use of recombinant factor VIIa in inherited platelet disorders [PDF]

, 2004
Mohamed Kaleelrahman, Adrian Minford, L. A. Parapia   +2 more
openalex   +1 more source

Microglial Fkbp5 Impairs Post‐Stroke Vascular Integrity and Regeneration by Promoting Yap1‐Mediated Glycolysis and Oxidative Phosphorylation

Advanced Science, EarlyView.
A post‐stroke perivascular niche of microglia characterized by low expression of M2 markers and elevated glycolysis, oxidative phosphorylation (OXPHOS), and phagocytic activity is identified, which is termed stroke‐activated vascular‐associated microglia (stroke‐VAM).
Yanan Li, Yanmei Qiu, Yunlei Yang, Yanhao Wei, Haokun Peng, Longhai Zeng, Pengcheng Li, Rentang Bi, Bo Hu   +8 more
wiley   +1 more source

A Conjugation Delivery System of Macrophages and Platelet Pharmacytes Promotes Regeneration After Spinal Cord Injury

Advanced Science, EarlyView.
A macrophage–platelet conjugation system (M‐P‐NPs@PPARγ) targets injure tissue to co‐deliver platelet mitochondria and PPARγ‐encoding NPs. This strategy boosts the macrophage energy supply and restores lipid homeostasis, leading to synergistically enhanced efferocytosis and tissue repair Abstract Mitochondrial dysfunction occurs in macrophages with ...
Haoli Wang, Hao Hu, Yijun Li, Lintao Hu, Chenhui Gu, Yiwei Zhu, Jing Huang, Na Li, Shuqi Jiang, Shouyan Zu, Jiachen Xu, Yining Wang, Ke Yang, Pengfei Chen, Liqing Shangguan, Yongcheng Wang, Shunwu Fan, Xianfeng Lin, Qingqing Wang   +18 more
wiley   +1 more source

Pregnancy and delivery outcomes in individuals with RUNX1-Familial Platelet Disorder. [PDF]

Br J Haematol
Deuitch NT, Haizler-Cohen L, Kajdic A, Bresciani E, Craft K, Davis J, Chong S, Young DJ, Liu PP.   +8 more
europepmc   +1 more source

Increased bleeding and thrombosis in myeloproliferative neoplasms mediated through altered expression of inherited platelet disorder genes

, 2023
Mitchell A, Frontini M, Islam S, Sivapalaratnam S, Krishnan A.   +4 more
europepmc   +1 more source

Update on diagnostic testing for platelet function disorders [PDF]

Catherine P.M. Hayward
openalex   +1 more source

Diagnostic utility of light transmission platelet aggregometry: results from a prospective study of individuals referred for bleeding disorder assessments [PDF]

, 2009
Catherine P.M. Hayward, Menaka Pai, Y. Liu, Karen A. Moffat, Jodi Seecharan, Kathryn E. Webert, Richard J. Cook, Nancy M. Heddle   +7 more
openalex   +1 more source

Microfluidic Electrochemical Biosensor for the Detection of Platelet Factor 4 Antibody‐Mediated Thrombotic Disorders

Advanced Science, EarlyView.
A microfluidic electrochemical biosensor enables sensitive and specific detection of antibodies associated with vaccine‐induced immune thrombotic thrombocytopenia (VITT) and heparin‐induced thrombocytopenia (HIT). The platform uses two antigen targets— platelet factor 4 (PF4) and cross‐linked‐PF4 (c‐PF4)—and microliter volumes of patient sera to ...
Diana F. Cedillo‐Alcantar, Adam Kanack, Seonhwa Lee, Alan M. Gonzalez‐Suarez, Kihak Gwon, Emily Mauch, Thi Thanh‐Qui Nguyen, Anand Padmanabhan, Alexander Revzin   +8 more
wiley   +1 more source