Results 211 to 220 of about 182,278 (349)

Whole Blood Serotonin Levels and Platelet 5-HT2A Binding in Autism Spectrum Disorder

open access: green, 2019
E. A. Aaron   +10 more
openalex   +2 more sources

An Engineered Solidified Peptide Hemocyte Sponge as Nanomotor Storage to Combat Bacterial Colitis

open access: yesAdvanced Science, EarlyView.
Peptides immobilized via nickel coordination can stabilize the framework structure. Following coating with red blood cell membranes, these constructs are capable of continuously sequestering endotoxins and mitigating colonic pathogenic damage by alleviating bacterial‐induced ferroptosis.
Yuxin Fang   +8 more
wiley   +1 more source

Clinical and laboratorial characterization of a cohort of patients with hereditary platelet disorders [PDF]

open access: gold
Letícia Dalla Vecchia Grassi   +5 more
openalex   +1 more source

Endothelial Cell‐Specific Molecule‐1 (ESM1): An Endogenous Anticoagulant and Protective Factor in Venous Thrombosis

open access: yesAdvanced Science, EarlyView.
This study identifies ESM1 as an endogenous anticoagulant that modulates venous thrombosis. It shows that ESM1 deficiency triggers vascular occlusion in zebrafish and mice, whereas its restoration or overexpression prolongs clot‐formation time. Mechanistic analyses reveal that ESM1 activates HCII through its dermatan‐sulfate chain, uncovering a ...
Changsheng Chen   +10 more
wiley   +1 more source

Efficacy of novel agents against cellular models of familial platelet disorder with myeloid malignancy (FPD-MM). [PDF]

open access: yesBlood Cancer J
Mill CP   +14 more
europepmc   +1 more source

Persons with Quebec platelet disorder have a tandem duplication of PLAU, the urokinase plasminogen activator gene [PDF]

open access: bronze, 2009
Andrew D. Paterson   +8 more
openalex   +1 more source

USP35 Acts as a Deubiquitinating Enzyme for ID3 to Promote Immune Escape in Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
USP35 stabilizes ID3 expression by deubiquitinating the K2/K30 site, thereby upregulating PD‐L1 and promoting immune escape in colorectal cancer. IU1, an inhibitor of USP35 enzyme activity, has been shown to inhibit USP35, thereby accelerating ID3 degradation, enhancing CD8+ T cell killing, and reversing the immunosuppressive microenvironment ...
Wenxin Chen   +9 more
wiley   +1 more source

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