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Expert Perspective: Hematologic Malignancies and Vasculitis
Arthritis &Rheumatology, EarlyView.
Michelle L. Robinette, Hetty E. Carraway
wiley +1 more source
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Blood Coagulation & Fibrinolysis, 2015
Thrombocytes or platelets are anucleated cells derived from megakaryocytes by process of megakaryopoiesis, with maturation time of 4-5 days. They are small and discoid in shape with size ranging from 2 to 4 μm. The platelet concentration in blood varies between 150, 000 and 400, 000 cells/μl of blood.
Vani Rajashekaraiah, Manasa Krishnegowda
openaire +5 more sources
Thrombocytes or platelets are anucleated cells derived from megakaryocytes by process of megakaryopoiesis, with maturation time of 4-5 days. They are small and discoid in shape with size ranging from 2 to 4 μm. The platelet concentration in blood varies between 150, 000 and 400, 000 cells/μl of blood.
Vani Rajashekaraiah, Manasa Krishnegowda
openaire +5 more sources
Pediatrics In Review, 2020
After vascular injury and exposure of subendothelial matrix proteins to the intravascular space, mediators of hemostasis are triggered and allow for clot formation and restoration of vascular integrity. Platelets are the mediators of primary hemostasis, creating a platelet plug and allowing for initial cessation of bleeding.
openaire +2 more sources
After vascular injury and exposure of subendothelial matrix proteins to the intravascular space, mediators of hemostasis are triggered and allow for clot formation and restoration of vascular integrity. Platelets are the mediators of primary hemostasis, creating a platelet plug and allowing for initial cessation of bleeding.
openaire +2 more sources
Migraine Is Not a Platelet Disorder
Headache: The Journal of Head and Face Pain, 1985SYNOPSISThe platelet theory of migraine causation predicts that drugs inhibiting platelet activation will be effective in migraine prevention, but the literature indicates that this is only partly the case. Conversely, therapy achieving clinical benefit should be associated with reduced platelet activity. To test this concept, the β‐adrenergic blockers
Rajiv Joseph +2 more
openaire +4 more sources
Pediatric and Developmental Pathology, 2019
Germline mutations in RUNX1 result in autosomal dominant familial platelet disorder with associated myeloid malignancy (FPDMM). To characterize the hematopathologic features associated with a germline RUNX1 mutation, we reviewed a total of 42 bone marrow
Karen M. Chisholm +8 more
semanticscholar +1 more source
Germline mutations in RUNX1 result in autosomal dominant familial platelet disorder with associated myeloid malignancy (FPDMM). To characterize the hematopathologic features associated with a germline RUNX1 mutation, we reviewed a total of 42 bone marrow
Karen M. Chisholm +8 more
semanticscholar +1 more source