Use of Targeted High-Throughput Sequencing for Genetic Classification of Patients with Bleeding Diathesis and Suspected Platelet Disorder. [PDF]
Andres O+18 more
europepmc +1 more source
Diagnostic utility of light transmission platelet aggregometry: results from a prospective study of individuals referred for bleeding disorder assessments [PDF]
Catherine P.M. Hayward+7 more
openalex +1 more source
Extracellular vesicles (EVs) derived from stem cells show promise for applications in regenerative medicine, but their scalability and yield remain challenges. This review explores the approaches for biophysical modulations within cell niches on EV properties, discusses the current clinical application of EVs, and provides an outlook on the existing ...
Yang Xu+9 more
wiley +1 more source
Regulation of platelet biogenesis: insights from the May–Hegglin anomaly and other MYH9-related disorders [PDF]
Z. Chen, Ramesh A. Shivdasani
openalex +1 more source
Serotonergic Modulators in Alzheimer's Disease: A Hope in the Hopeless Condition
ABSTRACT Alzheimer's disease (AD) is the main cause of dementia worldwide. AD is a progressive brain neurodegenerative disease due to genetic and environmental factors that induce a progressive accumulation of intracellular hyperphosphorylated tau protein and extracellular amyloid protein (Aβ).
Najlaa Hamed Almohmadi+7 more
wiley +1 more source
Strategies in Clinical and Laboratory Diagnosis of Inherited Platelet Function Disorders in Children [PDF]
Ralf Knöfler, Werner Streif
openalex +1 more source
ABSTRACT The subfamily Gomphrenoideae is composed of about 480 accepted species, many of which have been historically used as medicinal plants, reason why they have been studied in terms of chemical profile, biological activity, and safety. This review consolidates the advances in research on this subfamily over the past 47 years, emphasizing its ...
Dayanna Isabel Araque Gelves+3 more
wiley +1 more source
ABSTRACT Background Coronary slow flow and no reflow significantly predict poor prognosis in acute myocardial infarction (AMI) patients, especially those with chronic kidney disease (CKD). Early identification of factors contributing to these conditions can mitigate ischemic events and improve outcomes.
Hao Xu+5 more
wiley +1 more source
Platelet-Derived Growth Factor B Chain Is a Novel Target Gene of Cocaine-Mediated Notch1 Signaling: Implications for HIV-Associated Neurological Disorders [PDF]
Honghong Yao+3 more
openalex +1 more source
ABSTRACT Background Coronary artery vasospasm following coronary artery bypass grafting (CABG) is a rare but potentially life‐threatening complication that can lead to myocardial ischemia, arrhythmias, and cardiogenic shock. Nitroglycerin‐resistant vasospasm, particularly involving the left main coronary artery (LMCA), poses significant diagnostic and ...
Dina Soliman+3 more
wiley +1 more source