Results 281 to 290 of about 3,355,363 (341)
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Quantitative Platelet Disorders
Veterinary Clinics of North America: Small Animal Practice, 1988Thrombocytopenia may be caused by abnormal platelet production, accelerated removal owing to immunologic or nonimmunologic reasons, or sequestration of platelets in the spleen. Bleeding associated with thrombocytopenia usually presents as petechial or ecchymotic hemorrhages or epistaxis.
Karen J. Thomason +2 more
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Hematology/Oncology Clinics of North America, 2007
Congenital platelet disorders represent a rare group of diseases classified by either a qualitative or quantitative platelet defect. This article outlines the historical, clinical, laboratory, and genetic features of various inherited platelet disorders with attention given to updated information on disease classification, diagnosis, and genotypes.
Janna M. Journeycake, Cindy E. Neunert
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Congenital platelet disorders represent a rare group of diseases classified by either a qualitative or quantitative platelet defect. This article outlines the historical, clinical, laboratory, and genetic features of various inherited platelet disorders with attention given to updated information on disease classification, diagnosis, and genotypes.
Janna M. Journeycake, Cindy E. Neunert
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Clinical Cytometry for Platelets and Platelet Disorders
Clinics in Laboratory Medicine, 2023Clinical flow cytometry tests for inherited and acquired platelet disorders are useful diagnostic tools but are not widely available. Flow cytometric methods are available to detect inherited glycoprotein deficiencies, granule release (secretion defects), drug-induced thrombocytopenias, presence of antiplatelet antibodies, and pharmacodynamic ...
Andrew L, Frelinger +1 more
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Platelets and platelet disorders in Africa
Baillière's Clinical Haematology, 1992Blood platelets, which are known to play important roles in normal vertebrate biology, are influenced by a variety of factors, the majority of which are acquired. In this chapter, attention is drawn to the need to re-examine one of the old accepted values in haematology, the normal platelet count.
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Blood Reviews, 1988
Congenital platelet disorders include thrombocytopathies and thrombocytopenias, which often occur in association. Thrombocytopathies constitute a model for exploring platelet physiology at the molecular level: adhesion, activation, release phenomena, aggregation.
J.P. Caen, S. Bellucci
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Congenital platelet disorders include thrombocytopathies and thrombocytopenias, which often occur in association. Thrombocytopathies constitute a model for exploring platelet physiology at the molecular level: adhesion, activation, release phenomena, aggregation.
J.P. Caen, S. Bellucci
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Platelet function disorders [PDF]
Haemophilia, 2000 Platelet function defects comprise a large and heterogeneous group of bleeding disorders that range in severity from mild to severe. Patients may be asymptomatic; however, the majority who are diagnosed present with easy bruising and mucocutaneous bleeding, or with excessive haemorrhage following injury or surgery.
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Quebec platelet disorder: update on pathogenesis, diagnosis, and treatment.
Seminars in Thrombosis and Hemostasis, 2011Quebec platelet disorder (QPD) is an autosomal dominant bleeding disorder associated with reduced platelet counts and a unique gain-of-function defect in fibrinolysis due to increased expression and storage of urokinase plasminogen activator (uPA) by ...
J. Blavignac +3 more
semanticscholar +1 more source
The Lancet, 1981
The hypothesis that migraine is caused by a primary abnormality of platelet behaviour was investigated in a total of 77 migraine patients and control subjects. Platelets taken from patients with classical migraine during a headache-free period demonstrated significantly higher spontaneous platelet aggregation and platelet adhesion than platelets from ...
B. Wachowicz +3 more
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The hypothesis that migraine is caused by a primary abnormality of platelet behaviour was investigated in a total of 77 migraine patients and control subjects. Platelets taken from patients with classical migraine during a headache-free period demonstrated significantly higher spontaneous platelet aggregation and platelet adhesion than platelets from ...
B. Wachowicz +3 more
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Current Opinion in Hematology, 2003
Inherited platelet disorders are important causes of bleeding that can quantitatively and qualitatively alter platelets, impairing their function. The purpose of this review is to summarize current knowledge on the different types of inherited platelet disorders, their clinical and laboratory features, molecular genetic causes, and the therapies used ...
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Inherited platelet disorders are important causes of bleeding that can quantitatively and qualitatively alter platelets, impairing their function. The purpose of this review is to summarize current knowledge on the different types of inherited platelet disorders, their clinical and laboratory features, molecular genetic causes, and the therapies used ...
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2005
Publisher Summary Platelets are an important component in the first phase of hemostasis. This chapter gives a synoptic view of qualitative disorders of platelet function. When platelets are reduced in number, or become defective in function, bleeding may occur.
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Publisher Summary Platelets are an important component in the first phase of hemostasis. This chapter gives a synoptic view of qualitative disorders of platelet function. When platelets are reduced in number, or become defective in function, bleeding may occur.
openaire +2 more sources