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Acquired platelet disorders

Thrombosis Research, 2016
In contrast to congenital platelet disorders, which are rare, acquired platelet dysfunctions are more common in clinical practice. Their main causes are medications and systemic/hematologic diseases. Typical clinical manifestations are mucosal bleeding, epistaxis, or superficial epidermal bleeding normally of modest entity. In most cases, the molecular
Caterina Casari, Wolfgang Bergmeier
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Platelet Disorders in Pregnancy

Clinics in Perinatology, 1980
This article focuses on the platelet component of hemostasis during pregnancy, and on abnormalities in coagulation attributable to a decrease in platelet number, qualitative platelet function, or both. The restrictions that pregnancy imposes on the evaluation and treatment of these hemostatic abnormalities are emphasized.
Roberto Romero, Thomas P. Duffy
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Platelet Disorders in Adolescents

Journal of Pediatric and Adolescent Gynecology, 2010
Acquired and inherited platelet disorders can present with bleeding symptoms during adolescence. Platelet disorders include disorders of platelet number and disorders of platelet function. In adolescent females with platelet disorders, menorrhagia is a common presenting bleeding symptom.
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Platelet disorders in pregnancy

Current Opinion in Obstetrics and Gynecology, 2001
Before the advent of automated cell counters, thrombocytopenia was looked for and identified after a clinical question. With automation, thrombocytopenia in pregnancy was commonly found, and with its commonality its clinical meaning went out of focus. For the majority of women, thrombocytopenia is benign and, as a marker of fetal thrombocytopenia, the ...
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Platelet granule disorders

Critical Reviews in Oncology/Hematology, 1986
The present review has cataloged the inherited and acquired disorders of platelet granules. Unfortunately, a mere listing of different conditions in which dense bodies, alpha granules, or both are decreased, absent, or fused does little to define their importance in human platelet physiology or as a causative factor in hemorrhagic disease.
James G. White   +2 more
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Bernard-Soulier syndrome: an inherited platelet disorder.

Archives of Pathology & Laboratory Medicine, 2009
Bernard-Soulier syndrome is an inherited platelet disorder, which is transmitted in an autosomal recessive manner. This syndrome is characterized by variable thrombocytopenia and large defective platelets.
Angie Pham, Jun Wang
semanticscholar   +1 more source

Disorders of platelet function

Critical Reviews in Oncology/Hematology, 1996
Qualitative platelet disorders are described and reviewed above. The acquired platelet function defects are very common, and sometimes result in hemorrhage, especially in association with trauma or surgery. However, the specific biochemical defect is absent, and no characterized platelet abnormalities have been recognized.
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Inherited Disorders of Platelets

Hematology/Oncology Clinics of North America, 2013
Platelet membrane glycoproteins play a key role in hemostasis and thrombosis. Although disorders of platelet membrane glycoproteins are rare, their effects on the lives of those affected are very important. Severe deficiencies manifest themselves early during childhood with mucocutaneous bleeding.
Reyhan Diz-Kucukkaya   +3 more
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Inherited platelet disorders in women

Thrombosis Research, 2019
Inherited platelet disorders (IPD) are a heterogeneous group of hemorrhagic diseases affecting both men and women, but usually associated with more evident bleeding symptoms in women due to the exposure to sexspecific hemostatic challenges, like menstruation and delivery.
Gresele P, Falcinelli E, Bury L.
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Primary Platelet Disorders

1997
This chapter describes various aspects of primary platelet disorders. Platelets are small biconcave cells that are essential for adequate hemostasis. Platelet disorders can lead to both hemorrhagic and ischemic strokes. Platelet abnormalities can be divided into quantitative abnormalities or qualitative abnormalities of platelet function.
William M. Feinberg   +1 more
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