Results 301 to 310 of about 182,278 (349)
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Current Opinion in Hematology, 2003
Inherited platelet disorders are important causes of bleeding that can quantitatively and qualitatively alter platelets, impairing their function. The purpose of this review is to summarize current knowledge on the different types of inherited platelet disorders, their clinical and laboratory features, molecular genetic causes, and the therapies used ...
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Inherited platelet disorders are important causes of bleeding that can quantitatively and qualitatively alter platelets, impairing their function. The purpose of this review is to summarize current knowledge on the different types of inherited platelet disorders, their clinical and laboratory features, molecular genetic causes, and the therapies used ...
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Critical Reviews in Oncology/Hematology, 1986
The present review has cataloged the inherited and acquired disorders of platelet granules. Unfortunately, a mere listing of different conditions in which dense bodies, alpha granules, or both are decreased, absent, or fused does little to define their importance in human platelet physiology or as a causative factor in hemorrhagic disease.
James G. White, Harvey J. Weiss
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The present review has cataloged the inherited and acquired disorders of platelet granules. Unfortunately, a mere listing of different conditions in which dense bodies, alpha granules, or both are decreased, absent, or fused does little to define their importance in human platelet physiology or as a causative factor in hemorrhagic disease.
James G. White, Harvey J. Weiss
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Haemophilia, 2000
Platelet function defects comprise a large and heterogeneous group of bleeding disorders that range in severity from mild to severe. Patients may be asymptomatic; however, the majority who are diagnosed present with easy bruising and mucocutaneous bleeding, or with excessive haemorrhage following injury or surgery.
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Platelet function defects comprise a large and heterogeneous group of bleeding disorders that range in severity from mild to severe. Patients may be asymptomatic; however, the majority who are diagnosed present with easy bruising and mucocutaneous bleeding, or with excessive haemorrhage following injury or surgery.
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Hematology, 2005
Abstract The inherited platelet disorders are a heterogeneous collection of rare diseases that are infrequently encountered in clinical practice. They are, however, fascinating abnormalities, which have taught us a great deal about normal platelet biochemistry and physiology.
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Abstract The inherited platelet disorders are a heterogeneous collection of rare diseases that are infrequently encountered in clinical practice. They are, however, fascinating abnormalities, which have taught us a great deal about normal platelet biochemistry and physiology.
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InnovAiT: Education and inspiration for general practice, 2021
Platelets play a vital role in haemostasis; therefore, an increase or decrease in levels or a disorder of platelet function can lead to symptoms such as easy bruising and excessive bleeding, particularly from mucocutaneous sites. Patients may also report symptoms associated with the underlying condition.
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Platelets play a vital role in haemostasis; therefore, an increase or decrease in levels or a disorder of platelet function can lead to symptoms such as easy bruising and excessive bleeding, particularly from mucocutaneous sites. Patients may also report symptoms associated with the underlying condition.
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2018
The term ‘platelet disorder’ covers a very large and heterogeneous group of diseases that have a multitude of causes. Platelet disorders are either inherited or acquired and are due to an abnormality of platelet number (quantitative disorder), an abnormality of platelet function (qualitative disorder), or a combination of both.
Nicola Curry, Raza Alikhan
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The term ‘platelet disorder’ covers a very large and heterogeneous group of diseases that have a multitude of causes. Platelet disorders are either inherited or acquired and are due to an abnormality of platelet number (quantitative disorder), an abnormality of platelet function (qualitative disorder), or a combination of both.
Nicola Curry, Raza Alikhan
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Platelets and platelet disorders in Africa
Baillière's Clinical Haematology, 1992Blood platelets, which are known to play important roles in normal vertebrate biology, are influenced by a variety of factors, the majority of which are acquired. In this chapter, attention is drawn to the need to re-examine one of the old accepted values in haematology, the normal platelet count.
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DeckerMed Emergency Medicine, 2017
Hemostasis occurs in two steps: platelet plug formation followed by fibrin deposition. Platelet disorders cause incomplete or absent platelet plug formation. Platelets form in bone marrow and have an 8- to 9-day life span. A careful history and physical examination can distinguish between platelets or the coagulation cascade as the cause of deranged ...
Truman John Milling +2 more
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Hemostasis occurs in two steps: platelet plug formation followed by fibrin deposition. Platelet disorders cause incomplete or absent platelet plug formation. Platelets form in bone marrow and have an 8- to 9-day life span. A careful history and physical examination can distinguish between platelets or the coagulation cascade as the cause of deranged ...
Truman John Milling +2 more
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Disorders of platelet function
Disease-a-Month, 1992Platelets provide for primary hemostasis by forming a hemostatic plug at sites of vascular damage. They also provide a surface for the assembly of the coagulation protein complexes that generate thrombin, serve as a nidus for fibrin clots, and secrete factors involved in wound repair.
J S, Bennett, M A, Kolodziej
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Rinsho byori. The Japanese journal of clinical pathology, 2003
Platelets play important roles in thrombosis and hemostasis, and their abnormalities lead to hemostatic disorders or thrombotic diseases. Due to genetic technique development, the study of genetic factors related to the hereditary platelet dysfunction, and the evaluation of gene polymorphisms have been reported recently.
Tsukasa, Ohmori, Yutaka, Yatomi
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Platelets play important roles in thrombosis and hemostasis, and their abnormalities lead to hemostatic disorders or thrombotic diseases. Due to genetic technique development, the study of genetic factors related to the hereditary platelet dysfunction, and the evaluation of gene polymorphisms have been reported recently.
Tsukasa, Ohmori, Yutaka, Yatomi
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