Results 41 to 50 of about 3,441,901 (408)

Bernard Soulier syndrome: A case report from Pakistan

Clinical Case Reports, 2023
Key Clinical Message Bernard Soulier Syndrome should be suspected in patients with bleeding disorder symptoms and significant family history, where consanguineous marriages are common.
Iqra Effendi, Ahsan Nadeem, Sara Sarfraz, Mubasshar Shahid, Minaam Farooq, Ayush Anand   +5 more
doaj   +1 more source

A hopeful therapy for Niemann-Pick C diseases [PDF]

, 2017
Not abstract ...
Erickson, Robert P., Fiorenza, Maria Teresa   +1 more
core   +1 more source

Rituximab Twice Weekly for Refractory Thrombotic Thrombocytopenic Purpura in a Critically Ill Patient with Acute Respiratory Distress Syndrome

Case Reports in Oncology, 2020
Thrombotic thrombocytopenic purpura (TTP) is a rare, serious, life-threatening disease characterized by microangiopathic hemolytic anemia, thrombocytopenia, and hypercoagulability.
Bahjat Azrieh, Arwa Alsaud, Khaldun Obeidat, Amr Ashour, Seham Elebbi, Shehab F. Mohamed, Mohamed Adel Abdelaty, Abdelraouf Akkari, Abdurrahman Ali Elbuzidi, Mohamed A. Yassin   +9 more
doaj   +1 more source

Anti-platelet factor 4/polyanion antibodies mediate a new mechanism of autoimmunity [PDF]

, 2020
Antibodies recognizing complexes of the chemokine platelet factor 4 (PF4-CXCL4) and polyanions (P) opsonize PF4-coated bacteria hereby mediating bacterial host defense. A subset of these antibodies may activate platelets after binding to PF4-heparin complexes, causing the prothrombotic adverse drug reaction heparin-induced thrombocytopenia (HIT).
arxiv   +1 more source

Dental management considerations for the patient with an acquired coagulopathy. Part 1: Coagulopathies from systemic disease [PDF]

, 2003
Current teaching suggests that many patients are at risk for prolonged bleeding during and following invasive dental procedures, due to an acquired coagulopathy from systemic disease and/or from medications.
A Barber, AB Lumb, AD Kaye, AGG Turpie, AH Friedlander, AI Schafer, AM Ziffer, AS Gewirtz, AT Mailloux, BS Coller, C Kearon, CA Petruff, CH Mielke Jr., CL Norred, D Blinder, D Deykin, DB Petitti, DF Pawlak, DM Eisenberg, EM Hylek, F Catella-Lawson, FE Silverstein, G Palareti, G Russo, H Bagheri, H Ogiuchi, IW Scopp, J Gibson, J Harenberg, J Hirsh, J Hirsh, J Hirsh, J Leitch, J Marshall, JA Oates, JA Ware, JC O'Laughlin, JH Campbell, JN George, JN Saour, JR Vane, K Webster, L Bodner, L Mengle-Gaw, LC Tsen, LS Simon, M Akbarian, M Hurlen, M Levine, MH Eckman, MH Eckman, MJ Steinburg, MJ Troulis, MJ Wahl, MJ Wahl, MK Ang-Lee, MMW Koopman, N May, OR Beirne, P B Lockhart, P Devani, PC Amrein, PJ Sharis, R Benoliel, R De Caterina, R Hull, R Mulligan, R Mulligan, R Stern, RA Seymour, RE Alexander, RH White, RI Shorr, RT Weibert, S Cronberg, S Goldman, S H Pond, S Lippert, SC Cannegieter, SD Fihn, SE Lind, SE Lind, SI Rapaport, SJ Behrman, SR Cox, SS De Rossi, T Bandrowsky, TP Rooney, VA Ferraris, WR Bartle, WW Herman   +90 more
core   +1 more source

RUNX1 deficiency (familial platelet disorder with predisposition to myeloid leukemia, FPDMM).

Seminars in hematology (Print), 2017
In this review, we discuss disease-causing alterations of RUNT-related transcription factor 1 (RUNX1), a master regulator of hematopoietic differentiation. Familial platelet disorder with predisposition to myeloid leukemia (FPDMM) typically presents with
B. Schlegelberger, P. Heller
semanticscholar   +1 more source

Serotonin reuptake inhibitors and cardiovascular disease [PDF]

, 2005
Selective serotonin re-uptake inhibiting drugs (SSRIs) are widely used for endogenous depression. In addition to depleting the nerve terminals of serotonin they also lower blood platelet serotonin levels.
Belcher, P.R., Drake-Holland, A.J., Noble, M.   +2 more
core   +1 more source

Successful treatment of refractory gastrointestinal bleeding by systemic (oral) ankaferd blood stopper in a patient with Glanzmann thrombasthenia [PDF]

, 2015
Background: Glanzmann Thrombasthenia (GT) is a genetic platelet dysfunction and a life threatening disease. Ankaferd Blood Stopper (ABS) is a topical hemostatic agent of herbal origin which has been recently made available for clinical use.
Doğu, Mehmet Hilmi, Hacıoğlu, Sibel Kabukçu, Keskin, Ali, Sarı, İsmail   +3 more
core   +2 more sources

Platelet glycoprotein VI genetic quantitative and qualitative defects

Platelets, 2019
Platelet membrane glycoprotein VI (GPVI) is increasingly recognized as an important receptor for thrombus formation and growth. Numerous arguments have been published indicating that GPVI plays a major role in thrombosis without being essential for ...
Martine Jandrot-Perrus, Cedric Hermans, Diego Mezzano   +2 more
doaj   +1 more source

Rupture Forces among Human Blood Platelets at different Degrees of Activation [PDF]

, 2020
Little is known about mechanics underlying the interaction among platelets during activation and aggregation. Although the strength of a blood thrombus has likely major biological importance, no previous study has measured directly the adhesion forces of single platelet-platelet interaction at different activation states.
arxiv   +1 more source