Results 51 to 60 of about 3,348,298 (337)

Extracorporeal Catalytic Hemoperfusion Therapy for Refractory Septic Shock Using Ceria Nanoparticle‐Embedded Porous Microbeads

open access: yesAdvanced Functional Materials, EarlyView.
This study introduces an extracorporeal hemoperfusion system incorporating porous microbeads embedded with autocatalytic ceria nanoparticles (CeNPs) for targeted reactive oxygen species (ROS) scavenging in septic shock. The blood‐compatible hemoperfusion cartridge demonstrated significant improvements in survival, hemodynamic stability, and organ ...
Pilseon Im   +10 more
wiley   +1 more source

Treatment of critical bleeding events in patients with immune thrombocytopenia: a protocol for a systematic review and meta-analysis

open access: yesSystematic Reviews
Background Critical bleeding events in adults and children with ITP are medical emergencies; however, evidence-based treatment protocols are lacking. Due to the severe thrombocytopenia, (typically platelet count less than 20 × 109/L), a critical bleed ...
Emily Sirotich   +21 more
doaj   +1 more source

Platelet count in men with a habit of alcohol drinking

open access: yesPlatelets, 2020
Alcohol inhibits platelet function, and platelet count is often reduced in individuals with alcohol use disorder. However, the relation of habitual alcohol drinking with platelet count in a general population remains to be determined.
Ichiro Wakabayashi
doaj   +1 more source

Electric Pulse Regulated MXene Based Nanozymes for Integrative Bioelectricity Immuno‐Cancer Therapy

open access: yesAdvanced Functional Materials, EarlyView.
MXenzyme‐mediated bioelectricity cancer therapy (MXenzyme‐BECT) enhances cancer cell death through irreversible depolarization, ion channel disruption, ROS generation, and immunogenic cell death. Computational simulations reveal the electrical mechanisms by which MXenzyme acts on single cells and support to predict treatment parameters. Next‐generation
Sanghee Lee   +6 more
wiley   +1 more source

Optimizing Angiopep‐2 Density on Polymeric Nanoparticles for Enhanced Blood–Brain Barrier Penetration and Glioblastoma Targeting: Insights From In Vitro and In Vivo Experiments

open access: yesAdvanced Functional Materials, EarlyView.
The Angiopep‐2 peptide density on polymeric nanoparticles significantly impacts blood–brain barrier (BBB) penetration. This study explores this nuanced relationship using various in vitro models and in vivo assays, revealing that dynamic models better predict BBB penetration.
Weisen Zhang   +9 more
wiley   +1 more source

Decoding the Structure of Benzodithiophene Polymers for High‐Efficiency Organic Solar Cells

open access: yesAdvanced Functional Materials, EarlyView.
This study reveals a unique solid mesophase in top‐performing benzodithiophene‐based polymers for solar cells, comprising stacked solid‐like and liquid‐like layers. Combining nanoscale fibrillar domains with amorphous regions, it introduces a new structural paradigm.
Matteo Sanviti   +16 more
wiley   +1 more source

Platelet mitochondrial respiration and coenzyme Q10 could be used as new diagnostic strategy for mitochondrial dysfunction in rheumatoid diseases.

open access: yesPLoS ONE, 2021
IntroductionRheumatoid arthritis (RA) is a chronic inflammatory autoimunne disorder affecting both small and large synovial joints, leading to their destruction. Platelet biomarkers are involved in inflammation in RA patients.
Anna Gvozdjáková   +9 more
doaj   +1 more source

What to do when you suspect an inherited platelet disorder.

open access: yesHematology. American Society of Hematology. Education Program, 2011
Inherited platelet disorders (IPDs) comprise a heterogenous group of diseases that include defects in platelet function and disordered megakaryopoiesis.
Michele P. Lambert
semanticscholar   +1 more source

Unraveling Mixed‐Defect Transformations and Passivation Dynamics in Silicon Heterojunction Solar Cells

open access: yesAdvanced Functional Materials, EarlyView.
Defects in materials coexist in multiple forms, undergo dynamic transformations, and influence the material properties. Here, the dynamic transformations of passivation‐related defects in silicon heterojunctions are revealed through the decomposition of dual‐phase capacitance transients.
Do Hoe Kim   +17 more
wiley   +1 more source

Usefulness of multiple electrode aggregometry as a screening tool for bleeding disorders in a pediatric hospital

open access: yesPlatelets, 2019
Platelet function testing is a cornerstone in the diagnostic investigation of patients with a bleeding history. Multiple electrode aggregometry (MEA) has been shown to detect von Willebrand disease (VWD), platelet function disorders, and drug-induced ...
Thorsten Haas   +4 more
doaj   +1 more source

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