Results 91 to 100 of about 34,630 (270)

Added Prognostic Value of EEG Reactivity in Comatose Patients Following Cardiac Arrest

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To evaluate the added prognostic value of EEG reactivity for favorable outcome compared with background analysis during and after targeted temperature management (TTM). Methods Prospective observational cohort study of comatose post–cardiac arrest patients admitted to a single academic center between 2017 and 2022, all undergoing ...
Sarah Caroyer, Marie Obrecht, Charlotte de Maeseneire, Charlotte Damien, Chantal Depondt, Lorenzo Ferlini, Estelle Rikir, Filippo Annoni, Fabio Silvio Taccone, Nicolas Mavroudakis, Benjamin Legros, Nicolas Gaspard   +11 more
wiley   +1 more source

Blood collection, platelet isolation and measurement of platelet count and size in mice—a practical guide

Platelets, 2019
Inherited or acquired disorders of platelet production and function can result in thrombocytopenia and bleeding. Mouse models have proven useful for investigating the mechanisms that underlie these defects in humans. Precise methods for blood withdrawal,
Katja Aurbach, Markus Spindler, Elizabeth J. Haining, Markus Bender, Irina Pleines   +4 more
doaj   +1 more source

Measurement of primary hemostasis potential with platelet function analyzer to investigate the predictive effect on post-operative blood loss in cyanotic and acyanotic pediatric patients

, 2023
Aim: To investigate hemostatic parameters, including primary hemostasis potential in twenty pediatric patients with or without cyanosis undergoing cardio-pulmonary bypass (CPB) and cardiac surgery to repair congenital defects.
Akcevin, Atif, Er, Zafer Cengiz, Sal, Oguzhan, Ates, Mehmet Sanser, Tosya, Alper   +4 more
core   +1 more source

Safety and Tolerability of Givinostat: Evidence From Real‐World and Clinical Practice

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The aim of our study was to establish the prevalence of adverse events in a real‐world setting in boys living with Duchenne muscular dystrophy (DMD) treated with givinostat as part of an Expanded Access Program (EAP) in Italy. Methods The cohort included 90 ambulant boys, with age when treatment started between 6 and 23 years (mean ...
Marika Pane, Anna Capasso, Chiara Arpaia, Adele D’Amico, Emilio Albamonte, Federica Trucco, Maria Sframeli, Riccardo Masson, Francesca Magri, Luca Bello, Romina Venditti, Claudia Dosi, Michela Catteruccia, Michele Tosi, Claudio Bruno, Sonia Messina, Giacomo Comi, Elena Pegoraro, Valeria A. Sansone, Eugenio Mercuri   +19 more
wiley   +1 more source

Neurosurgical bleeding in platelet storage pool disorder: a case report

Platelets
Dense-granule deficiency (DGD) is an inherited platelet disorder due to the absence of dense granules essential for activation of platelets in the event of vascular injury.
Clifford Pierre, Kirsten W. Alcorn, Dong Chen, Joanna Fesler, Daniel Landis, Zachary N. Litvack, Barbara A. Konkle, Livia Hegerova   +7 more
doaj   +1 more source

Open heart surgery: Management of nonsurgical bleeding in the peri-operative period; 31/2-years institutional experience

Nigerian Journal of Medicine, 2017
BACKGROUND: Excessive perioperative bleeding remains a major complication following open heart surgery, resulting in increased morbidity and mortality of some patients in our institution.
I A Nwafor, M N Nwafor, J C Eze, N Ezemba, J M Chinawa, O C Nzewi, C I Ngene   +6 more
doaj   +1 more source

More on: platelet function analyzer (PFA)‐100® closure time in the evaluation of platelet disorders and platelet function [PDF]

Journal of Thrombosis and Haemostasis, 2006
J, Koscielny, H, Kiesewetter, G-F, von Tempelhoff   +2 more
openaire   +2 more sources

Recurrent Hypothermia and Autonomic Dysfunction Secondary to Shapiro Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT A 44‐year‐old man presented with recurrent hypothermia, diaphoresis and hypertension. Extensive investigation for infectious, inflammatory, metabolic and endocrine aetiologies was negative. MR scan of the brain demonstrated no lesions but revealed callosal dysgenesis, consistent with Shapiro syndrome.
Naveen Kumar, Jeremy Johnson, Susanne Watkins, Eoin Mulroy   +3 more
wiley   +1 more source

Novel Platelet Function Analyzer 200 Predicts Blood Transfusion After Elective Cardiac Surgery in Patients Suspended on Dual Antiplatelet Therapy. [PDF]

Clin Appl Thromb Hemost, 2023
Cui W, Zhang J, Wu Y, Yang W, Gao R, Yang Y, Yuan J, Zhao X.   +7 more
europepmc   +1 more source

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird, Haley McQuown, Jihyun Park, Samuel J. Teener, Ian F. Webber‐Davis, Andrew D. Carter, Dae‐Gyu Jang, Eva L. Feldman, Stephen A. Goutman, Benjamin J. Murdock   +9 more
wiley   +1 more source