Results 231 to 240 of about 34,630 (270)

Monitoring aspirin therapy with the Platelet Function Analyzer‐100

Scandinavian Journal of Clinical and Laboratory Investigation, 2008
Low platelet response to aspirin has been reported to be associated with a high incidence of vascular events. The reported prevalence of aspirin low-responsiveness varies, which may be explained by poor reproducibility of the methods used to evaluate aspirin response and low compliance.
Mortensen, Jette, Poulsen, Tina Svenstrup, Grove, Erik; id_orcid 0000-0002-1466-0865, Refsgaard, Jens, Nielsen, Helle Ladefoged, Pedersen, Susanne, Hedegaard, Sofie, Hvas, Anne-Mette, Kristensen, Steen Dalby   +8 more
openaire   +4 more sources

Using the Platelet Function Analyzer-100 for monitoring aspirin therapy

Thrombosis Research, 2007
The aim of the study was to evaluate the test characteristics of the Platelet Function Analyzer-100 (PFA-100) in patients treated with aspirin.The study consisted of two sub-studies. In study 1, 10 patients with ischemic heart disease (IHD) and 10 controls had platelet function assessed by optical platelet aggregation and the PFA-100 method in two 5 ...
Poulsen, Tina Svenstrup, Mickley, Hans, Korsholm, Lars, Licht, Peter Bjørn; id_orcid 0000-0003-1270-8068, Haghfelt, Torben, Jørgensen, Bo   +5 more
openaire   +4 more sources

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In vitro testing of platelets using the thromboelastogram, platelet function analyzer, and the clot signature analyzer to predict the bleeding time

Transfusion and Apheresis Science, 2006
Platelet aggregation, thromboxane A2 production and platelet annexin V binding are in vitro tests used to assess platelet function. This study was done to evaluate the clot signature analyzer (CSA), platelet function analyzer (PFA), and thromboelastogram (TE) as in vitro tests to predict the template bleeding time (BT).Twelve normal volunteers were ...
C Robert Valeri, Gina Ragno
exaly   +3 more sources

Platelet function analyzer (PFA-100): A tool to quantify congenital or acquired platelet dysfunction

Translational Research, 2001
PRINCIPLE OF THE TEST SYSTEM The instrument aspirates a blood sample under constant vacuum from the sample reservoir through a capillary and a microscopic aperture (147 μm) cut into the membrane. The membrane is coated with CEPI or CADP. The presence of these platelet activators and the high shear rates (5000 to 6000 s–1) under the standardized flow ...
B Jilma
exaly   +3 more sources

Platelet Function Analyzer

, 2019
The platelet function analyzer (PFA) test measured platelet aggregate formation under high shear rates and with addition of either collagen/epinephrine (A) or collagen/adenosine diphosphate (B) as agonists.
Connie H Miller
exaly   +2 more sources

Monitoring of Aspirin (ASA) Pharmacodynamics with the Platelet Function Analyzer PFA-100®

Thrombosis and Haemostasis, 2000
SummaryAnti-platelet drug therapy is currently performed without monitoring, because the established method of platelet aggregometry is cumbersome. The recently developed platelet function analyzer PFA-100® measures shear stress dependent, collagen ...
Monika Homoncik, P Stohlawetz, W Speiser   +2 more
exaly   +2 more sources

Platelet Function Analyzer: Shear Activation of Platelets in Microchannels

Biomedical Microdevices, 2003
Platelet function is suggestive of pathological conditions in cardiovascular diseases. With current insufficient prognostic devices, the need exists for a device to assess complete platelet function. This work presents a preliminary microfluidic device for such analysis based on platelet adhesion under shear flow conditions.
Ameya S. Kantak, Bruce K. Gale, Yuri Lvov, Steven A. Jones   +3 more
openaire   +1 more source

Platelet Function Analyzed by Light Transmission Aggregometry

2017
Analysis of platelet function is widely used for diagnostic work-up in patients with increased bleeding tendency. During the last decades, platelet function testing has also been introduced for evaluation of antiplatelet therapy, but this is still recommended for research purposes only.
Hvas, Anne-Mette, Favaloro, Emmanuel J
openaire   +3 more sources