Results 41 to 50 of about 34,630 (270)

Platelet abnormalities in patients with Parkinson's disease undergoing preoperative evaluation for deep brain stimulation

Scientific Reports, 2022
Normal hemostatic function is important for reduction of the risk of intracranial hemorrhage during stereotactic neurosurgery including deep brain stimulation (DBS) surgery.
Sheng-Che Chou, Chun-Hwei Tai, Sheng-Hong Tseng   +2 more
doaj   +1 more source

Platelet Dysfunction in Primary Thrombocythemia Using the Platelet Function Analyzer, PFA-100 [PDF]

American Journal of Clinical Pathology, 2005
We measured platelet function by standard aggregometric tests and by the PFA-100 (Dade Behring, Newark, DE) in samples from 55 patients with primary thrombocythemia (PT) and 26 healthy volunteers. Platelet function was evaluated in platelet-rich plasma by aggregation tests.
Jesús M, Cesar, Dunia, de Miguel, Angel, García Avello, Carmen, Burgaleta   +3 more
openaire   +2 more sources

The Antiplatelet Action of S-Nitroso Human Serum Albumin in Whole Blood

Biomedicines, 2022
Nitric oxide donors (NO-donors) have been shown to have therapeutic potential (e.g., ischemia/reperfusion injury). However, due to their release rate/antiplatelet properties, they may cause bleeding in patients.
Melina Tsiountsioura, Gerhard Cvirn, Axel Schlagenhauf, Harald Haidl, Kathrin Zischmeier, Nicole Janschitz, Martin Koestenberger, Willibald Wonisch, Margret Paar, Thomas Wagner, Eva-Christine Weiss, Seth Hallström   +11 more
doaj   +1 more source

Platelet Aggregation in Healthy Participants is Not Affected by Smoking, Drinking Coffee, Consuming a High-Fat Meal, or Performing Physical Exercise

Clinical and Applied Thrombosis/Hemostasis, 2019
Platelet aggregation can be measured using optical aggregation (light transmission aggregometry, LTA) as well as by impedance (Multiplate analyzer). The LTA (the gold standard method) can be influenced by many preanalytical variables.
Joyce P.M. Krekels BSc, Paul W.M. Verhezen Ing, Yvonne M.C. Henskens PhD, MSc   +2 more
doaj   +1 more source

Platelet, Fibrinolytic and Other Coagulation Abnormalities in Newly-Diagnosed Patients with Chronic Thromboembolic Pulmonary Hypertension

Diagnostics, 2022
The pathophysiological background of chronic thromboembolic pulmonary hypertension (CTEPH) has not been fully elucidated. Evidence suggests that abnormal platelet function and ineffective fibrinolysis may play a key role in the development of the disease.
Eleni Vrigkou, Argirios Tsantes, Dimitrios Konstantonis, Evdoxia Rapti, Eirini Maratou, Athanasios Pappas, Panagiotis Halvatsiotis, Iraklis Tsangaris   +7 more
doaj   +1 more source

Platelet Distribution Width Is Associated with P-Selectin Dependent Platelet Function: Results from the Moli-Family Cohort Study

Cells, 2021
Defined as an index of platelet size heterogeneity, the platelet distribution width (PDW) is still a poorly characterized marker of platelet function in (sub)clinical disease.
Benedetta Izzi, Alessandro Gialluisi, Francesco Gianfagna, Sabatino Orlandi, Amalia De Curtis, Sara Magnacca, Simona Costanzo, Augusto Di Castelnuovo, Maria Benedetta Donati, Giovanni de Gaetano, Marc F. Hoylaerts, Chiara Cerletti, Licia Iacoviello, on behalf of the Moli-family Study Investigators   +13 more
doaj   +1 more source

Whole Blood Platelet function Assay on the /CHOR

, 2023
The role of platelets as the initial defense against insult to the vasculature is well established. Moreover, platelets are now recognized as having a critical role in the acute care settings of cardiopulmonary bypass (CPB) procedures and cardiac ...
Michael Corsello, David G.M. Carville, Mark M. Walsh, Patricia A. Schleckser, Kirk E. Guyer   +4 more
core   +1 more source

Clinical Application and Evaluation of Preoperative Bleeding Tendency using Platelet Function Analyzer (PFA)-100. [PDF]

Archives of Aesthetic Plastic Surgery, 2013
Routine preoperative tests such as BT/CT, PT/PTT and CBC, could not test abnormal hemostasis that take drugs and health functional food. We used platelet function analyzer (PFA®)-100, to evaluate preoperative bleeding tendencies.
Jihu Han, Eon Rok Do, Tae Seob Kim, Chen Zhang, Dae Hwan Park   +4 more
doaj   +1 more source

A Rapid Platelet Function Assay Used to Regulate Platelet Transfusion Prophylaxis Following Cardiopulmonary Bypass Surgery

, 2023
Subsequent to cardiac surgery with cardiopulmonary bypass (CPB), patients are at risk of postoperative bleeding caused by acquired defects associated with the procedure. As such, many patients receive prophylactic blood product transfusion.
David T. Pearman, David G.M. Carville, Kathy E. Shaffer, Robert S. Galen   +3 more
core   +1 more source

Effects of clopidogrel and prednisone on platelet function in healthy dogs

Journal of Veterinary Internal Medicine, 2020
Background Glucocorticoids cause hypercoagulability, but it is unknown if they counteract clopidogrel's antiplatelet effects. Hypothesis/Objectives Determine the effects of clopidogrel and prednisone on platelet function. Animals Twenty‐four healthy dogs.
John Thomason, Allison P. Mooney, Joshua M. Price, Jacqueline C. Whittemore   +3 more
doaj   +1 more source