Results 301 to 310 of about 102,308 (347)

Role of activation-dependent platelet membrane glycoproteins in development of subacute occlusive coronary stent thrombosis.

Coronary Artery Disease, 1997
BACKGROUND Platelets have an important role in coronary thrombosis. METHODS We studied 151 consecutive patients undergoing implantation of Palmaz-Schatz stents because of suboptimal results after coronary balloon angioplasty treated by intense ...
M. Gawaz, Franz‐Josef Neumann, I. Ott, A. May, Silja Rüdiger, A. Schömig   +5 more
semanticscholar   +1 more source

Glycoproteins of the Platelet Plasma Membrane

1985
The glycoproteins of the platelet plasma membrane, in common with those of the plasma membranes of other cells, have an important role in the interaction of platelets with their environment and in particular in the platelet’s function of hemostasis.
openaire   +2 more sources

Monoclonal Antibodies against Platelet Membrane Glycoproteins IIb/IIIa and Ibα Inhibit Platelet Dependent Thrombin Generation by Different Mechanisms

Thrombosis and Haemostasis, 2000
Summary The antithrombotic effect of antiplatelet agents is principally due to their anti-aggregatory action, but these agents may also interfere with coagulation.
Stephen Thomas, P. Metcalfe, Alison H. Goodall, E. Gray   +3 more
semanticscholar   +1 more source

Structure and function of platelet membrane glycoproteins [PDF]

, 1993
Platelets are involved in a variety of cellular interactions that occur during the hemostatic and inflammatory responses to tissue injury. These include adhesion to extracellular matrix proteins (e.g. von Willebrand factor, collagen, fibronectin, vitronectin, laminin), homotypic interaction with each other to form a platelet plug, and heterotypic ...
openaire   +1 more source

Polymorphisms of Human Platelet Membrane Glycoproteins: Structure and Clinical Significance

Thrombosis and Haemostasis, 1995
The haemostatic response of platelets of any one individual will be influenced by the genetic profile of the total population of receptors expressed on the platelet surface.
A. Nurden
semanticscholar   +1 more source

Expression of platelet parameters and platelet membrane glycoproteins in childhood Burkitt lymphoma

Leukemia Research, 2019
Platelet activation and functional changes in some haematological malignancies have been investigated with little or no known documentation on Burkitt lymphoma (BL). Abnormalities of platelets contribute to either haemorrhage or thrombotic episodes which are life-threatening in patients with BL.
Renate Asare, Clement Opoku- Okrah, Kwabena Owusu Danquah, Ohene Opare-Sem, Otchere Addai-Mensah, Daniel Gyamfi, Francis Agyei Amponsah, Edward Yaw Afriyie, Richard Vikpebah Duneeh, David Ntiamoah Ofosu, Michael Frimpong   +10 more
openaire   +4 more sources

Fixation with formaldehyde induces expression of activation dependent platelet membrane glycoproteins, P selectin (CD62) and GP53 (CD63)

British Journal of Haematology, 1993
Summary. Platelet activation in vivo is important in the pathogenesis of thrombosis. Accurate measurement is difficult due to artefactual in vitro preparation related activation.
M. Cahill, M. Macey, A. Newland
semanticscholar   +1 more source

Membrane glycoproteins of endothelial cells and platelets

1987
Considerable evidence now supports an active role for vascular endothelial cells in the initiation and control of various physiological and pathophysiological processes including hemostasis, thrombosis, inflammation and immunological processes. Several events associated with these processes occur at the endothelial cell plasma membrane level.
J. Zandbergen-Spaargaren, O. C. Leeksma, J. A. Van Mourik, JC Giltay   +3 more
openaire   +2 more sources

Platelet membrane glycoprotein V: Characterization of the thrombin-sensitive glycoprotein from human platelets

Thrombosis Research, 1989
Human platelets contain a single membrane glycoprotein which is susceptible to thrombin proteolysis, glycoprotein V. We have purified 1 mg of glycoprotein V from 10(13) platelets using a combination of gel filtration, hydroxylapatite and ion-exchange chromatographies. Glycoprotein V has a blocked amino-terminus.
Rasheeda S. Zafar, Daniel A. Walz
openaire   +3 more sources

Regulation of platelet membrane levels of glycoprotein VI by a platelet-derived metalloproteinase

Blood, 2004
Thrombosis can be initiated when activated platelets adhere to injured blood vessels via the interaction of subendothelial collagen with its platelet receptor, glycoprotein (GP) VI. Here we observed that incubation of platelets with convulxin, collagen, or collagen-related peptide (CRP) resulted in GPVI signaling-dependent loss of surface GPVI and the ...
Jane Frances Arthur, Jane Frances Arthur, Robert K. Andrews, Robert K. Andrews, Mark L. Kahn, Mark L. Kahn, Michael C. Berndt, Michael C. Berndt, Elizabeth E. Gardiner, Elizabeth E. Gardiner   +9 more
openaire   +3 more sources