Results 51 to 60 of about 364,763 (251)

Effect of Subclinical Hypothyroidism on the Mean Platelet Volume of Pregnant Women

Medicine Science, 2016
Subclinical hypothyroidism (SH) is a frequently seen clinical disorder, which needs to be managed strictly in the pregnant population. SH is closely related with newborn complications and also suggested to be risk factor for cardiovascular events.
Oktay Sari, Alpaslan Tanoglu, Onur Mahmutoglu, Umit Aydogan, Fatma Beyazit, Yasam Kemal Akpak, Ugur Keskin   +6 more
doaj   +1 more source

Ischaemic strokes in patients with pulmonary arteriovenous malformations and hereditary hemorrhagic telangiectasia: associations with iron deficiency and platelets. [PDF]

, 2014
BackgroundPulmonary first pass filtration of particles marginally exceeding ∼7 µm (the size of a red blood cell) is used routinely in diagnostics, and allows cellular aggregates forming or entering the circulation in the preceding cardiac cycle to lodge ...
AD Kjeldsen, AD Kjeldsen, AE Guttmacher, AJ Easey, B Barzilai, B Nieswandt, Basel Chamali, BD Butler, BJ Folz, BM Silva, C Coupland, C Shovlin, CJ Gallione, CL Shovlin, CL Shovlin, CL Shovlin, CL Shovlin, CL Shovlin, CL Shovlin, CL Shovlin, CL Shovlin, Claire L. Shovlin, DW Johnson, E Buscarini, ER Chilvers, ER Weibel, F Roked, Gillian Angus, H Finnamore, Hannah C. Tighe, HL Devlin, IS Anand, J Feinstein, J Parra, J Remy, JA Dutton, JA Feinstein, JA Livesey, James E. Jackson, JE Van de Pette, JJ Mager, JL Hart, John A. Livesey, John Meek, K Clark, K Hara, K Nanthakumar, K Ono, K Zukotynski, KL Furie, Klaus Brusgaard, LC Weng, LS Valberg, M Bajc, M Billinger, M Blomley, M Moussouttas, M Nakayama, M Yeung, ME Faughnan, Michael A. Laffan, MK Whyte, MW van Gent, MW van Gent, OS AAssar, P Gazzaniga, P Gupta, P Shovlin CL, Wilmshurst, PC Hébert, RD Thompson, RF Gillum, Richard Manning, S Jackson, S Uchiyama, S Velthuis, SM Bang, T Krings, T Ueki, V Cottin, Vatshalan Santhirapala, WB Porter, Y Benjamini, Y Shinohara, Z Hao   +83 more
core   +3 more sources

Changes in Immune‐Inflammation Status and Acute Ischemic Stroke Prognosis in Prospective Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Inflammation is a critical risk factor for poor outcomes in cerebral infarction. Prior studies focused primarily on baseline inflammation status, neglecting dynamic longitudinal changes. We try to investigate the association between immune‐inflammation status alterations and stroke prognosis, and evaluated three systemic biomarkers'
Songfang Chen, Wenting Huang, Yitian Liu, Xuan Chen, Buyu Ke, Qian Shen, Hanyu Cai, Jing Sun, Yan Li, Yungang Cao, Beilei Hu, Keyang Chen   +11 more
wiley   +1 more source

Changes in platelet parameters in leukocytosis

The Pan African Medical Journal, 2016
INTRODUCTION: in recent years, platelets are known to have a large variety of functions in many pathophysiological processes and their interaction with endothelial cells and leukocytes is known to play an important role in the pathophysiology of vascular
Nurinnisa Ozturk, Nurcan Kilic Baygutalp, Ebubekir Bakan, Gulsum Feyza Altas, Harun Polat, Emrullah Dorman   +5 more
doaj   +1 more source

The actin binding proteins cortactin and HS1 are dispensable for platelet actin nodule and megakaryocyte podosome formation [PDF]

, 2016
A dynamic, properly organised actin cytoskeleton is critical for the production and haemostatic function of platelets. The Wiskott Aldrich Syndrome protein (WASp) and Actin-Related Proteins 2 & 3 Complex (Arp2/3 complex) are critical mediators of ...
Bem, Danai, Finney, Brenda, Machesky, Laura M., Poulter, Natalie S., Thomas, Steven G., Watson, Stephen P.   +5 more
core   +4 more sources

Exploratory Analysis of ELP1 Expression in Whole Blood From Patients With Familial Dysautonomia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Familial dysautonomia (FD) is a hereditary neurodevelopmental disorder caused by aberrant splicing of the ELP1 gene, leading to a tissue‐specific reduction in ELP1 protein expression. Preclinical models indicate that increasing ELP1 levels can mitigate disease manifestations.
Alejandra González‐Duarte, Lucy Norcliffe‐Kaufmann, Maria Luisa Cotrina, Zenith Khan, Kaia Dalamo, Patricio Millar Vernetti, Matthew Lawless, Elisabetta Morini, Monica Salani, Marla Weetall, Jana Narasimhan, Agostino G. Rocha, Susan A. Slaugenhaupt, Horacio Kaufmann   +13 more
wiley   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

The relationship between vitamin D levels, D-dimer and platelet parameter levels in patients with gestational hypertension

Frontiers in Immunology
IntroductionHypertension during pregnancy is a common pregnancy complication that has an important impact on maternal and fetal health. In recent years, studies have shown that vitamin D, D dimers and platelet parameters may play a key role in the ...
Pingping Wang, Jin Yao, Yaqiong Li, Zhanjun Zhang, Ruiling Zhang, Shouting Lu, Meixia Sun, Xiaorong Huang   +7 more
doaj   +1 more source

Safety and efficacy of eculizumab in adult and pediatric patients with aHUS, with or without baseline dialysis [PDF]

, 2015
C
Hourmant, Maryvonne, Kincaid, John F, Legendre, Christophe M, Menne, Jan, van de Kar, Nicole CAJ, Vande Walle, Johan   +5 more
core   +1 more source

Tolerance and safety of the potentially probiotic strain Lactobacillus rhamnosus PRSF-L477 : a randomised, double-blind placebo-controlled trial in healthy volunteers [PDF]

, 2010
In Europe, the species Lactobacillus rhamnosus is currently on the Qualified Presumption of Safety list used by the European Food Safety Authority (EFSA) for internal safety assessment, but according to the EFSA the species should remain a topic of ...
Huys, Geert, Klare, Ingo, Knol, Jan, Tolboom, Hermien, Wind, Richèle D   +4 more
core   +3 more sources