Results 1 to 10 of about 96,906 (352)

Increased platelet reactivity in idiopathic pulmonary fibrosis is mediated by a plasma factor. [PDF]

PLoS ONE, 2014
Idiopathic Pulmonary Fibrosis (IPF) is a progressive, incurable fibrotic interstitial lung disease with a prognosis worse than many cancers. Its pathogenesis is poorly understood.
Michael G Crooks, Ahmed Fahim, Khalid M Naseem, Alyn H Morice, Simon P Hart   +4 more
doaj   +20 more sources

Flavanols and Platelet Reactivity [PDF]

Clinical and Developmental Immunology, 2005
Platelet activity and platelet‐endothelial cell interactions are important in the acute development of thrombosis, as well as in the pathogenesis of cardiovascular disease. An increasing number of foods have been reported to have platelet‐inhibitory actions, and research with a number of flavanol‐rich foods,
Teresa Paglieroni, Carl L. Keen, Harold H. Schmitz, Dietrich Rein, Roberta R. Holt, Debra A. Pearson   +5 more
doaj   +4 more sources

Platelet Reactivity in the Exacerbation of Psoriasis. [PDF]

J Clin Med
Background: Psoriasis is a chronic, inflammatory, immune-mediated disease with a specific cutaneous presentation. Increased platelet aggregation has been observed in patients with extensive psoriatic lesions. The aim of this study was to evaluate the clinical factors affecting platelet reactivity in patients with an exacerbation of psoriasis.
Adamski P, Adamska U, Buszko K, Sikora J, Czajkowski R.   +4 more
europepmc   +3 more sources

Perioperative platelet reactivity over time in patients undergoing vascular surgery: An observational pilot study. [PDF]

PLoS ONE
BackgroundDespite Antiplatelet therapy (APT), cardiovascular patients undergoing revascularisation remain at high risk for thrombotic events. Individual response to APT varies substantially, resulting in insufficient protection from thrombotic events due
A R T Brand Kanters, N C Roozendaal, N M J Parr, G Pasterkamp, R T Urbanus, S J A Korporaal, Gert J de Borst   +6 more
doaj   +2 more sources

Immature Platelets and Platelet Reactivity in Patients with COVID-19. [PDF]

Clin Appl Thromb Hemost
Coronavirus disease 2019 (COVID-19) is associated with a high incidence of thromboembolic events, both venous and arterial. There are currently no specific clinical or laboratory markers to guide antithrombotic therapy for COVID-19 patients. Immature platelets represent a population of hyper-reactive platelets associated with arterial thrombotic ...
Balmakov Y, Mark T, Barnett I, Cipok M, Lev EI, Cohen A, Aviram E, Mayo A.   +7 more
europepmc   +3 more sources

IFITM3 regulates fibrinogen endocytosis and platelet reactivity in nonviral sepsis [PDF]

The Journal of Clinical Investigation, 2022
Platelets and megakaryocytes are critical players in immune responses. Recent reports suggest infection and inflammation alter the megakaryocyte and platelet transcriptome to induce altered platelet reactivity.
Robert A. Campbell, Bhanu Kanth Manne, Meenakshi Banerjee, Elizabeth A. Middleton, Abigail Ajanel, Hansjorg Schwertz, Frederik Denorme, Chris Stubben, Emilie Montenont, Samantha Saperstein, Lauren Page, Neal D. Tolley, Diana L. Lim, Samuel M. Brown, Colin K. Grissom, Douglas W. Sborov, Anandi Krishnan, Matthew T. Rondina   +17 more
doaj   +2 more sources

Genetics of predicted platelet reactivity.

Blood, 2023
de Vries PS.
europepmc   +3 more sources

Unfavorable Dynamics of Platelet Reactivity during Clopidogrel Treatment Predict Severe Course and Poor Clinical Outcome of Ischemic Stroke

Brain Sciences, 2021
Background: Previous studies have revealed that high platelet reactivity while on clopidogrel may affect the severe course and worse prognosis of ischemic stroke. However, the above findings were based on a single measurement of platelet function.
Adam Wiśniewski, Joanna Sikora, Aleksandra Karczmarska-Wódzka, Joanna Bugieda, Karolina Filipska, Robert Ślusarz   +5 more
doaj   +1 more source

Baseline Platelet Activation and Reactivity in Patients with Critical Limb Ischemia. [PDF]

PLoS ONE, 2015
Patients with critical limb ischemia (CLI) have a high risk to develop cardiovascular events (CVE). We hypothesized that in CLI patients platelets would display increased baseline activation and reactivity.We investigated baseline platelet activation and
Peter Paul Wisman, Martin Teraa, Gert Jan de Borst, Marianne C Verhaar, Mark Roest, Frans L Moll   +5 more
doaj   +1 more source

Pre-operative platelet reactivity is a strong, independent predictor of bleeding complications after branched endovascular thoracoabdominal aortic aneurysm repair

Platelets, 2022
Endovascular aortic repair (EVAR) an alternative to open surgical repair of thoracoabdominal aortic aneurysm (TAAA). The effect of EVAR on platelet reactivity is unknown.
Aleksandra Gąsecka, Mateusz Zawadka, Anna Burban, Aleksandra Idzik, Agata Gelo, Agata Graczyńska, Katarzyna Jama, Krzysztof J. Filipiak, Tomasz Jakimowicz   +8 more
doaj   +1 more source