Results 221 to 230 of about 102,294 (349)

A Lung‐Immune Dual‐Humanized Mouse Using Cryopreserved Tissue Enables Infection and Immune Profiling of Human Common Cold Coronaviruses

Advanced Science, EarlyView.
Cryopreserved lung‐humanized mice overcome the dependency to fresh tissues and permit head‐to‐head profiling of all four human common cold coronaviruses versus SARS‐CoV‐2 infection; the model validates Paxlovid efficacy against HKU1 and, when coupled with human immune‐system engraftment, enables interrogation of lung‐resident human immunity and HKU1 ...
Chunyu Cheng, Jing Sun, Chun Lu, Qian Yu, Yiyun He, Bingqing Wu, Deshan Ren, Shuai Ding, Jincun Zhao, Yan Li   +9 more
wiley   +1 more source

Platelet Reactivity and Fibrin Clot-Strength as assessed by TEG in Patients with Atrial Fibrillation undergoing Percutaneous Coronary Intervention. [PDF]

J Cardiovasc Transl Res
Gjermeni D, Vetter H, Szabó S, Anfang V, Juelch C, Leggewie S, Hesselbarth D, Jäckel M, Duerschmied D, Trenk D, Westermann D, Olivier CB.   +11 more
europepmc   +1 more source

Microglial Fkbp5 Impairs Post‐Stroke Vascular Integrity and Regeneration by Promoting Yap1‐Mediated Glycolysis and Oxidative Phosphorylation

Advanced Science, EarlyView.
A post‐stroke perivascular niche of microglia characterized by low expression of M2 markers and elevated glycolysis, oxidative phosphorylation (OXPHOS), and phagocytic activity is identified, which is termed stroke‐activated vascular‐associated microglia (stroke‐VAM).
Yanan Li, Yanmei Qiu, Yunlei Yang, Yanhao Wei, Haokun Peng, Longhai Zeng, Pengcheng Li, Rentang Bi, Bo Hu   +8 more
wiley   +1 more source

The Lung and Winding Road: Inflammation-Driven Platelet Reactivity in Long COVID. [PDF]

JACC Basic Transl Sci
Roweth HG.
europepmc   +1 more source

Low RBC counts predict high on-treatment platelet reactivity in patients undergoing percutaneous coronary intervention and treated with clopidogrel. [PDF]

J Biomed Res, 2023
Gu Q, Wang Q, Hua R, Zhang W, Teng J, Ma J, Dong Z, Gong X, Li C.   +8 more
europepmc   +1 more source

Piperlongumine Blocks JAK2-STAT3 to Inhibit Collagen-Induced Platelet Reactivity Independent of Reactive Oxygen Species†

, 2015
Hengjie Yuan, Katie Houck, Ye Tian, Uddalak Bharadwaj, Ken Hull, Zhou Zhou, Mingzhao Zhou, Xiaoping Wu, David J. Tweardy, Daniel Romo, Xiaoyun Fu, Yanjun Zhang, Jianning Zhang, Jing-fei Dong   +13 more
openalex   +2 more sources

Ultrasound‐Boosted Liposomal Prodrug Overcomes Age‐Associated Biodistribution Disparity in Pediatric Solid Tumor Therapy

Advanced Science, EarlyView.
The age‐associated disparity of nanocarrier biodistribution limits the nanotherapeutics of childhood solid tumors. This study developed an ultrasound‐activated liposomal prodrug (CSCPTL) to overcome the age‐associated disparity of off‐target distribution.
Danfei Chen, Junjun Xu, Jian Chen, Jue Hu, Xiaobo Xuan, Haifang Cai, Mingdong Yang, Zhuxian Zhou, Guowei Wang   +8 more
wiley   +1 more source

Prediction of the short-term prognosis of acute ischaemic stroke in patients with high treatment platelet reactivity using explainable machine learning. [PDF]

Sci Rep
Liu J, Gu Y, Wang D, Xia X, Li X.
europepmc   +1 more source

Decreased Platelet Reactivity and Function in a Mouse Model of Human Pancreatic Cancer. [PDF]

Thromb Haemost, 2023
Kawano T, Hisada Y, Grover SP, Schug WJ, Paul DS, Bergmeier W, Mackman N.   +6 more
europepmc   +1 more source

Differential Inhibition of Platelet Reactivity by Dual Therapy With Aspirin and Low-Dose Rivaroxaban in Peripheral Arterial Disease: A Pilot Study

, 2022
Kerstin Jurk, Korbinian F. Rothenaicher, Kathrin Groß, Heidi Rossmann, Gerhard Weißer, Irene Schmidtmann, Thomas Münzel, Christine Espinola–Klein   +7 more
openalex   +1 more source