Results 241 to 250 of about 102,294 (349)

Ir(III) Complexes Convert Cold to Hot Tumors via Ferroptosis/Necroptosis‐Driven Immunogenic Cell Death and Photosensitized CD47 Downregulation

Advanced Science, EarlyView.
Red‐light‐activated Ir1 overcomes hypoxia tolerance and adapts to the immunosuppressive tumor microenvironment, converting immunologically cold tumors into inflamed hot microenvironments. This conversion is driven by synergistic induction of immunogenic cell death through coordinated ferroptosis‐necroptosis pathways and spatiotemporally controlled ...
Long‐Bo Yu, Peng Wang, Qing‐Hua Shen, Qi‐Xin Guan, Zhi‐Yuan Li, Ying‐Ying Han, Xin‐Yi Zhang, Qing‐Yuan Hu, Cai‐Ping Tan   +8 more
wiley   +1 more source

Roles of miR-223 in Platelet Function and High On-Treatment Platelet Reactivity: A Brief Report and Review. [PDF]

Genes (Basel)
Askari S, Goldfinger LE.
europepmc   +1 more source

Modulating Integrin and Growth Factor Signaling With Peptides: Strategies to Synergistically Enhance Bone Tissue Regeneration

Advanced Science, EarlyView.
It has been demonstrated that, in the bone extracellular matrix (ECM), integrins and growth factor receptors (GFRs) engage in synergistic signaling to guide bone healing and regeneration. This review provides a comprehensive overview of current strategies using ECM‐derived peptides to recreate the cellular microenvironment and harness synergistic ...
Lluís Oliver‐Cervelló, Elisabetta Ada Cavalcanti‐Adam, Carlos Mas‐Moruno   +2 more
wiley   +1 more source

Platelet Reactivity in the Exacerbation of Psoriasis. [PDF]

J Clin Med
Adamski P, Adamska U, Buszko K, Sikora J, Czajkowski R.   +4 more
europepmc   +1 more source

Amodiaquine Enhances Anti‐Melanoma Efficacy of Attenuated Salmonella via Targeting Glutathione Reductase in Neutrophils

Advanced Science, EarlyView.
This study shows that Salmonella VNP20009 recruits pro‐tumor neutrophils that reduce its anticancer efficacy. Combining VNP with amodiaquine selectively eliminates these neutrophils by targeting glutathione reductase. A GR‐shRNA‐loaded VNP strain was further developed, demonstrating an innovative strategy integrating drug repurposing with synthetic ...
Wanfa Dong, Chunyuan Zhao, Chengxi Li, Lin Weng, Zehan Ji, Peiqi Li, Jiqiang Lu, Danni Liu, Anni Yu, Tianyi Jiang, Shaokai Huang, Heng Liu, Xiao Chen, Zichun Hua   +13 more
wiley   +1 more source

Platelet reactivity to adenosine diphosphate and <i>CYP2C19</i> genotypes are linked with carotid plaques and may predict carotid plaque stability in acute ischemic stroke patients. [PDF]

Neurosciences (Riyadh)
Shi H, Tang M, Wang T, Yang L, Lai X, Chen Y, Diao F, Chen X, Zuo J, Xu J, Zhong G, Dong Y.   +11 more
europepmc   +1 more source

PLATELET REACTIVITY IN METABOLIC SYNDROME: RELATIONSHIP BETWEEN GLYCEMIC CONTROL, OBESITY AND ON-TREATMENT PLATELET REACTIVITY

Journal of the American College of Cardiology, 2014
Slater, J, Alviar, CL, Kumar, V, Burdowski, J, Gianos, E, Berger, J, Balakrishnan, R, Vani, A, Guo, Y, Xu, J, Schwartzbard, A, Sedlis, S, Shah, B   +12 more
openaire   +3 more sources

Neutrophil-Lymphocyte Ratio (Nlr) and Platelet -Lymphocyte Ratio (Plr) may be superior to C-Reactive Protein (Crp) for predicting the occurrence of differentiated thyroid cancer [PDF]

, 2016
Sevilay Özmen, Özge Timur, İlknur Çalık, Konca Altınkaynak, Elif Zipak, Eda Şimşek, Faruk Yıldız, Hakan Sevimli, Hakan Gözcü, Abdulmuttalip Arslan, Ayşe Çarlıoğlu   +10 more
openalex   +1 more source

PRDM1+ Malignant Cells Mediate an Immunosuppressive Landscape and Resistance to Neoadjuvant Chemoradiotherapy and Immunotherapy in Esophageal Squamous Cell Carcinoma

Advanced Science, EarlyView.
Integrated scRNA‐seq, scTCR‐seq analysis, and functional assays identify PRDM1+ malignant epithelial cells with hyper lipid peroxidation characteristics that demonstrate reduced responsiveness to the nICRT treatment. Principal factor PRDM1 activates cysteine metabolism genes to modulate lipid peroxidation (an intrinsic cellular pathway related to ...
Dijian Shen, Rui Li, Yong She, Xuefei Liu, Yuanyang Huang, Yongling Ji, Keying Chen, Zhengbo Song, Runzhe Chen, Xuan Li, Qi Zhao, Qixun Chen, Ming Chen   +12 more
wiley   +1 more source

Impact of haemoglobinA1c on platelet reactivity and cardiovascular outcomes in patients undergoing drug-eluting stent implantation. [PDF]

Sci Rep
Wu Y, Jiang X, Jiang L, Ji H, Liu M, Li W.   +5 more
europepmc   +1 more source