Results 21 to 30 of about 103,858 (377)
Romiplostim use in pregnant women with immune thrombocytopenia
American Journal of Hematology, Volume 98, Issue 1, Page 31-40, January 2023., 2023 Abstract Treatment for immune thrombocytopenia (ITP) in pregnancy is hampered by the lack of fetal safety evidence of maternally‐administered medications. The Pregnancy Surveillance Program (PSP) collected patient information from 2017–2020 for pregnancy, birth outcomes, and adverse events (AEs) for 186 women exposed to romiplostim from 20 days before ...
James B. Bussel +7 more
wiley +1 more source
Predicting the Need for Blood Transfusion in Intensive Care Units with Reinforcement Learning [PDF]
, 2022 As critically ill patients frequently develop anemia or coagulopathy, transfusion of blood products is a frequent intervention in the Intensive Care Units (ICU). However, inappropriate transfusion decisions made by physicians are often associated with increased risk of complications and higher hospital costs.
arxiv +1 more source
American Journal of Hematology, Volume 98, Issue 2, Page 272-281, February 2023., 2023 Abstract Patients with relapsed/refractory (R/R) higher‐risk myelodysplastic syndromes (MDS) have a dismal median overall survival (OS) after failing hypomethylating agent (HMA) treatment. There is no standard of care for patients after HMA therapy failure; hence, there is a critical need for effective therapeutic strategies.
Amer M. Zeidan +18 more
wiley +1 more source
Platelet Biochemistry and Morphology after Cryopreservation [PDF]
, 2020 Platelet cryopreservation has been investigated for several decades as an alternative to room temperature storage of platelet concentrates. The use of dimethylsulfoxide as a cryoprotectant has improved platelet storage and cryopreserved concentrates can ...
Compernolle, Veerle +2 more
core +1 more source
BJUI Compass, Volume 4, Issue 1, Page 88-95, January 2023., 2023 Abstract Objectives The objective of this study is to present our initial experience with a novel parenchymal clamp (NPC) developed to allow partial nephrectomies (PN) to be performed without whole kidney ischaemia. We compare patients who underwent PN with the NPC with those undergoing standard PNs. Methods The NPC applies pressure only to the portion
James Macneil +3 more
wiley +1 more source
Microfluidic flow chambers using reconstituted blood to model hemostasis and platelet transfusion in vitro [PDF]
, 2016 Blood platelets prepared for transfusion gradually lose hemostatic function during storage. Platelet function can be investigated using a variety of (indirect) in vitro experiments, but none of these is as comprehensive as microfluidic flow chambers.
Compernolle, Veerle +4 more
core +2 more sources
Zhongguo shuxue zazhi, 2023 Objective To study the correlation between platelet transfusion efficacy and KIR receptor-HLA ligand. Methods Thirty-three leukemia patients with positive HLA antibody were tested for cross-matching with donor platelets.
Yu HAN +12 more
doaj +1 more source
Platelet Transfusion: An Update on Indications and Guidelines [PDF]
, 2021 Platelets are commonly transfused either therapeutically or prophylactically to maintain hemostasis. Most platelet transfusions are used to manage patients with hematologic malignancies.
Otrock, Zaher K, Yuan, Shan
core +1 more source
Platelet kinetics after slow versus standard transfusions: A pilot study [PDF]
, 2011 Background. Platelet transfusion is required in the acute phase of some thrombocytopenic disorders in order to prevent potentially dangerous hemorrhages.
Abbas Habibi +18 more
core +2 more sources
Medicina, 2023 Background and Objectives: Patients undergoing liver transplantation (LT) often require increased blood product transfusion due to pre-existing coagulopathy and intraoperative fibrinolysis.
Mohmad H. Alsabani +5 more
doaj +1 more source