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Platelet Transfusion Therapy

Hematology/Oncology Clinics of North America, 1990
This article reviews appropriate platelet support of those patients who are chronically thrombocytopenic because of decreased platelet production, including those receiving chemotherapy or radiation treatments and those undergoing bone marrow transplants.
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Platelet Transfusion Therapy

Hematology/Oncology Clinics of North America, 2013
Platelet transfusion therapy has become an integral part of the treatment of patients with hematological and solid tumor malignancy receiving chemotherapy. Since its introduction almost 60 years ago, several advances and refinements have been introduced in the collection, storage, and administration to improve the safety and efficacy of platelet ...
Vahid Afshar-Kharghan   +1 more
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Blood Platelets and Platelet Transfusions

Archives of Internal Medicine, 1961
The application of quantitative biological and biochemical methods to the study of the blood platelets has led to revolutionary developments in our understanding of these elusive structures. 1 Until recently platelets were often regarded as non-cellular in nature, although it has long been known that they are of cellular origin.
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Optimizing platelet transfusions

Current Opinion in Hematology, 2015
Platelet transfusion remains a challenging procedure. Concerns about bacterial contamination and other complications, and the interest in improving the evidence base for criteria for platelet transfusion thresholds and policies have provided impetus for studies that challenge the status quo.
Kyle Annen, Jordan E. Olson
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Overview of Platelet Transfusion

Seminars in Hematology, 2010
Most platelet transfusions are given to prevent bleeding in thrombocytopenic patients undergoing chemotherapy for malignancy or hematopoietic stem cell transplant. In stable, uncomplicated patients the risk of bleeding is similar until the platelet count falls to
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Platelet Transfusion Therapy

Clinics in Laboratory Medicine, 1996
Although platelet transfusion is a vital part of modern hemotherapy, many related issues are unresolved. The most appropriate trigger point of transfusion and the clinical utility of prophylactic transfusion are still debated, but the importance of patient-specific transfusion decisions is clear.
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Platelet Transfusions in Pediatrics

New England Journal of Medicine, 1957
THE transfusion of fresh human platelets has been shown to be an effective and practical way to control the hemorrhagic episodes in thrombocytopenia.1 Recently a variety of technics have been devised for the preparation of platelet concentrates that permit prompt infusion of therapeutically effective amounts of platelets without the delay or ...
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Platelet serology and transfusion

Human Pathology, 1983
Various methods of detecting platelet antibodies have been developed relatively recently. This review describes assays in current use and their application to clinical practice, particularly in the management of alloimmunized recipients of platelet transfusions.
Judith A. Harmon, William V. Miller
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Platelet transfusion therapy

Journal of Clinical Apheresis, 2001
AbstractThe relative merits of apheresis platelets and platelet concentrates are undergoing debate due to evolving issues of safety, inventory, and cost. The application of photochemical inactivation technology may eliminate any rationale for the use of apheresis platelets rather than pooled platelet concentrates, so that the relative merits of these ...
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Platelet Transfusion Therapy

JAMA: The Journal of the American Medical Association, 1965
The safety and hemostatic effects of platelet transfusions have been well demonstrated in a National Cancer Institute—Acute Leukemia Task Force supported collaborative study among five major institutions and the National Laboratories of the American Red Cross.
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