Results 71 to 80 of about 4,108 (201)

Assessing Liver and Iron Markers in Steady State Pediatric SCD Patients to Ascertain the Hepatic Consequences of Hemotransfusion: A Case‐Control Study in Ghana

Health Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background and Aims Between 200,000 and 300,000 children with sickle cell disease (SCD) are born in Africa every year, with 75%–80% of these children living in sub‐Saharan Africa. In newborns with SCD, significant iron accumulations may develop because of their increased risk of requiring multiple blood transfusions. This study aimed to assess
John Agyemang Sah, Stephen Twumasi, Allwell Adofo Ayirebi, Benedict Sackey, Enoch Odame Anto, Richard Vikpebah Duneeh, Ebenezer Senu, Veronica Barnor, David Boakye, Daniel Nii Martey Antonio, Wina Ivy Ofori Boadu   +10 more
wiley   +1 more source

Platelet-to-lymphocyte ratio (PLR) and Plateletcrit (PCT) in young patients with morbid obesity [PDF]

Revista da Associação Médica Brasileira, 2019
SUMMARY OBJECTIVE To compare the complete blood counts, namely the plateletcrit (PCT) and Platelet-To-Lymphocyte Ratio (PLR) of healthy subjects and those with morbid obesity in the young population. METHODS We included 45 patients with morbid obesity (body mass index -BMI - greater than or equal to 45 kg/m2) and 45 healthy subjects (BMI less than ...
Emrah Erdal, Mehmet İnanir
openaire   +3 more sources

The Role of Extracellular Vesicles in Transient Ischaemic Attacks and Ischaemic Stroke: A Systematic Review

Journal of Extracellular Biology, Volume 5, Issue 3, March 2026.
Both transient ischaemic attack (TIA) and ischaemic stroke lead to an increase in individual cellular‐derived populations of extracellular vesicles (EVs), including endothelial, platelet and leukocyte derived. These EVs have downstream roles in the pathophysiological events associated with TIA and stroke, including dysregulated inflammation and ...
Rebecca Marie Raven, Philip Eurig James, Keith Morris, Jessica Olivia Williams   +3 more
wiley   +1 more source

An overview of platelet indices for evaluating platelet function in children with scorpion envenomation [PDF]

, 2014
The aim of this study was to assess the correlation between platelet indices and scorpion envenomations (SE). Medical records of 76 children who were hospitalised for scorpion stings in the paediatric intensive care unit (PICU) between February 2013 and ...
Colak, Pinar, Konca, Capan, Tekin, Mehmet, Turgut, Mehmet, Uckardes, Fatih   +4 more
core  

Thrombocyte indices and plateletcrit in dogs with primary immune-mediated hemolytic anemia [PDF]

Medycyna Weterynaryjna, 2019
Primary immune-mediated hemolytic anemia (IMHA) is one of the most common autoimmune disorders in dogs. Platelet indices in dogs with IMHA have not been commonly used in daily clinical practice. The purpose of this study was to evaluate trombocyte indices, including platelet count (PLT), mean platelet volume (MPW), platelet size deviation width (PDW ...
Çolakoğlu, Ekrem Çağatay, Haydardedeoğlu, Ali Evren   +1 more
openaire   +2 more sources

Discovery of a Novel DNMT1 Inhibitor with Improved Efficacy in Treating β‐Thalassemia

Advanced Science, Volume 13, Issue 11, 23 February 2026.
Context of Research: β‐thalassemia affects millions worldwide. DNMT inhibitors are effective HbF‐inducers that benefit patients with β‐thalassemia. Existing DNMT inhibitors are not approved for β‐thalassemia treatment due to dose‐limiting toxicity.What We Find: DMT207 traps DNMT1 into helix‐kinked inactive conformation and enhances its interaction with
Yijie Shen, Jiale Wei, Shibing Tang, Dongliang Wu, Liangyi Zong, Shuyuan Ma, Qing Xiong, Ruijie Gong, Siyuan Xu, Chuxuan Peng, Qin Feng, Songchen Liu, Qitong Liu, Yuhua Ye, Quan Zhao, Cheng Luo, Peng Huang, Zhihai Li, Xiangqian Kong, Xianjiang Lan   +19 more
wiley   +1 more source

Platelet indices and the risk of pulmonary arterial hypertension: a two-sample and multivariable Mendelian randomization study

Frontiers in Cardiovascular Medicine
BackgroundRecent epidemiological studies have indicated a correlation between platelet indices and pulmonary arterial hypertension (PAH), yet the causality between them remains unclear. To explore the causal relationship between four platelet indices and
Yinuo Li, Xi Liu, Qian Hong, Rui Xu
doaj   +1 more source

Reference intervals for platelet indices in seniors and frequency of abnormal results in a population-based setting: a comparison between directly and indirectly estimated reference intervals

Journal of Laboratory Medicine, 2021
Mean platelet volume (MPV), platelet distribution width (PDW), and plateletcrit (PCT) possess diagnostic and prognostic capabilities in a variety of diseases. We aimed to establish reference intervals (RI) for platelet indices (PI) in seniors.
Hermann Wolfgang, Risch Lorenz, Grebhardt Chris, Nydegger Urs E., Sakem Benjamin, Imperiali Mauro, Renz Harald, Risch Martin   +7 more
doaj   +1 more source

Platelet indices in type 1 diabetes mellitus [PDF]

, 2019
Aim: We aimed to compare platelet counts (Plt), plateletcrit (PCT) and platelet distribution width (PDW) values of type 1 diabetes mellitus (T1DM) patients with those of healthy subjects.
Gunes, Yilmaz, Inanir, Mehmet, Sincer, Isa   +2 more
core   +2 more sources

The Dual Associations of Peripheral Inflammatory Cells With Brain Reorganization in Insular Gliomas With/Without Epilepsy: An Exploratory Analysis

CNS Neuroscience &Therapeutics, Volume 32, Issue 2, February 2026.
Legend process. (A,B) Based on deep learning and virtual brain grafting, we revealed that the brain could conduct reorganization to adopt insular glioma with/without epilepsy, which was not influenced by tumor features and was associated with peripheral inflammatory cells.
Hongfang Zhao, Bohan Zhang, Qifeng He, Zhenghai Deng, Zonggang Hou, Jian Xie   +5 more
wiley   +1 more source