Results 121 to 130 of about 638,324 (358)

Aspirin-dependent effects on purinergic P2Y1 receptor express [PDF]

open access: yes, 2019
Chronic treatment with aspirin in healthy volunteers (HVs) is associated with recovery of adenosine diphosphate (ADP)-induced platelet activation. The purinergic P2Y1 receptor exerts its effects via a Gq-protein, which is the same biochemical pathway ...
Alemanno, Laura   +8 more
core   +1 more source

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

open access: yesAdvanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi   +4 more
wiley   +1 more source

Confetti Ordering by Polymer Brushes [PDF]

open access: yesarXiv, 2015
I consider the ordering of dilute platelet additives when incorporated into an end-grafted polymer brush. The competition between wetting interactions and the anisotropic stress environment of the interior of the brush causes these platelet additives to either remain suspended at the outer edge of the brush laying flat against the brush surface (as ...
arxiv  

Moisture absorption and diffusivity of epoxy filled layered-structure nanocomposite [PDF]

open access: yes, 2014
This paper studies moisture absorption and diffusivity of epoxy reinforced layered structure nanocomposites and its effect on fracture toughness. Two different types of layered fillers employed in the study were clay and graphene platelets, in which both
Araby, Sherif   +3 more
core  

When are platelets just platelets? [PDF]

open access: yesBlood, 2006
Comment on Kiefel et al, page [3761][1] Severe thrombocytopenia in a 1- to 2-day-old neonate is an emergency situation because of the especially high rate of intracranial hemorrhage. In this issue of Blood , Kiefel and colleagues demonstrate that random donor platelets are often effective (24 of ...
openaire   +2 more sources

Murine Models and Human Cell Line Models to Study Altered Dynamics of Ovarian Follicles in Polycystic Ovary Syndrome

open access: yesAdvanced Biology, EarlyView.
The manuscript examines preclinical murine and human models to study polycystic ovary syndrome (PCOS), delving into the cellular and molecular mechanisms underlying altered ovarian follicular dynamics. It explores the cellular interactions involved in normal and PCOS ovaries and outlines the current and novel strategies in the search for preclinical ...
Arturo Bevilacqua   +5 more
wiley   +1 more source

Revealing the γ′ and γ″ Phase Fractions of Additively Manufactured and Differently Heat‐Treated Nickel‐Base Superalloy IN718 by Atom Probe Tomography and Their Impact on Mechanical Properties

open access: yesAdvanced Engineering Materials, EarlyView.
Additive manufacturing is a promising route for the production of Ni‐base superalloys for turbine applications, such as Inconel 718. Nonetheless, it induces various changes in the microstructure and performance of these materials. One such change is the incidence of the δ‐Ni3Nb phase, whose impact on microstructure, aging precipitate fractions, and ...
Guilherme Maziero Volpato   +8 more
wiley   +1 more source

Electrically Insulating Electromagnetic Interference Shielding Materials: A Perspective

open access: yesAdvanced Functional Materials, EarlyView.
Developing electromagnetic interference (EMI) shielding materials with inherent electrical insulation and high EMI shielding effectiveness is challenging but important for electronic applications. This perspective summarizes the recent advancements in designing electrically insulating EMI shielding materials and discusses the underlying mechanisms of ...
Ji Liu, Valeria Nicolosi
wiley   +1 more source

A Novel Protein‐Polysaccharide Oral Nanoemulsion Targeting Activated Hepatic Stellate Cells to Enhance the Therapeutic Effect of Pirfenidone on Fibrosis After Transarterial Chemoembolization for Liver Cancer

open access: yesAdvanced Functional Materials, EarlyView.
Transarterial Chemoembolization (TACE) may aggravate liver fibrosis. In this study, a novel oral targeting nanoemulsion is fabricated to enhance the therapeutic effect of antifibrotic drug‐pirfenidone (PFD) on fibrosis after TACE. Studies have shown that PFD nanoemulsion can enhance the oral liver targeting effect of PFD, and effectively improve the ...
Zhimei Cheng   +12 more
wiley   +1 more source

Developing a computational model of blood platelets with fluid dynamics applications [PDF]

open access: yesarXiv, 2012
This paper worked towards modeling blood platelets. Blood platelets, also known as thrombocytes, play a key role in blood clotting which is a vital human function. Furthermore, the role of these entities in strokes, myocardial infarctions, and coronary artery disease add to the importance of blood platelets.
arxiv  

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