Therapeutic nano‐drug delivery systems interact with cellular mitochondria in a multitude of ways. While the complexity of such interactions disrupts the mitochondrial electron transport chain and increases reactive oxygen species production, thereby contributing to nanoparticle toxicity, they also present unique theranostic opportunities in diseases ...
Sourav Bhattacharjee
wiley +1 more source
Regulation of platelet contractility by agonists present across a thrombus. [PDF]
Hiebner DW +9 more
europepmc +1 more source
Protein Corona Formation on Soft Nanocarriers Under Biomimetic Circulatory Flow
A biomimetic venous circulation system is developed to study protein corona formation on soft nanocarriers under physiological shear. Liposomes, PLGA nanoparticles, and lipid‐polymer hybrid nanoparticles acquire largely shared but material‐dependent protein coronas that alter surface properties and suppress cellular uptake, highlighting the importance ...
Anamarija Nikoletić +7 more
wiley +1 more source
A monoclonal antibody to platelet αIIbβ3 that inhibits protein disulfide isomerase binding and platelet aggregation. [PDF]
Wang L, Wang J, Li J, Coller BS.
europepmc +1 more source
Shape Memory Polymer‐Based Flexible Pressure Sensor for Real‐Time Venous Thrombosis Monitoring
A shape‐memory tubular flexible pressure sensor with a 100‐mesh microstructured SMP‐PLA/MWCNTs sensing layer was developed for PICC‐mounted monitoring of thrombosis‐related pressure changes. The sensor combines high sensitivity (204 kPa−1), a fast response time (28 ms), and conformal catheter fixation and was validated by hydrostatic and ex vivo ...
Yi Chen +7 more
wiley +1 more source
P-Selectin and Platelet-Monocyte Interaction in Inflammation: Mechanisms, Hypothesis, and Open Questions. [PDF]
Fernandes MKC +5 more
europepmc +1 more source
Waterborne polyurethane/graphene formulations are developed as piezoresistive coatings on glass fabric to enable flexible strain sensing. The graphene‐enabled conductive network provides a stable electromechanical response under cyclic compression. The coating demonstrates reliable pressure‐dependent resistance changes, highlighting its potential for ...
Vishnu Vijayan Pillai +8 more
wiley +1 more source
αvβ3 CAR-T Cells Simultaneously Targeting Tumor and Metastases Produce Highly Effective Control in Preclinical Models of Melanoma and Triple-Negative Breast Cancer. [PDF]
Cobb DA +10 more
europepmc +1 more source
ABSTRACT Molybdenum disulfide (MoS2) has attracted attention as a promising material due to the growing demand for environmentally friendly, cost‐effective, and efficient water treatment techniques. With its physicochemical characteristics, this stratified bidimensional material allows it to be highly effective in adsorption and catalytic performance ...
Pariksha Bishnoi +4 more
wiley +1 more source
From escort to target, the multidimensional roles and prospects of platelets in tumor immune checkpoint inhibitor therapy. [PDF]
Xiao J +5 more
europepmc +1 more source

