Results 11 to 20 of about 771,873 (354)

Assessment of neonatal, cord, and adult platelet granule trafficking and secretion

open access: yesPlatelets, 2020
Despite the transient hyporeactivity of neonatal platelets, full-term neonates do not display a bleeding tendency, suggesting potential compensatory mechanisms which allow for balanced and efficient neonatal hemostasis.
Anh T. P. Ngo   +12 more
doaj   +1 more source

Platelet-mediated metabolism of the common dietary flavonoid, quercetin. [PDF]

open access: yes, 2010
BACKGROUND: Flavonoid metabolites remain in blood for periods of time potentially long enough to allow interactions with cellular components of this tissue.
Bernice Wright   +5 more
core   +7 more sources

Analysis of adenoviral attachment to human platelets

open access: yesVirology Journal, 2009
Background Systemic adenoviral (Ad) vector administration is associated with thrombocytopenia. Recently, Ad interaction with mouse platelets emerged as a key player determining liver uptake and platelet clearance.
Urieli-Shoval Simcha   +5 more
doaj   +1 more source

Young steady-state rabbit platelets do not have an enhanced capacity to expose procoagulant phosphatidylserine

open access: yesPlatelets, 2018
Platelets are recognized to be physiologically and functionally heterogeneous. An example of the diversity in reactivity is the formation of a distinct subpopulation of procoagulant phosphatidylserine (PS)-exposing platelets upon activation. Platelet age
Emily C. Reddy   +4 more
doaj   +1 more source

The trans-sialidase from Trypanosoma cruzi induces thrombocytopenia during acute Chagas' disease by reducing the platelet sialic acid contents [PDF]

open access: yes, 2005
Strong thrombocytopenia is observed during acute infection with Trypanosoma cruzi, the parasitic protozoan agent of American trypanosomiasis or Chagas' disease.
Campetella, O.   +4 more
core   +2 more sources

Humanized mouse models for inherited thrombocytopenia studies

open access: yesPlatelets, 2023
Inherited thrombocytopenia (IT) is a group of hereditary disorders characterized by a reduced platelet count as the main clinical manifestation, and often with abnormal platelet function, which can subsequently lead to impaired hemostasis.
Xiaojie Wang   +13 more
doaj   +1 more source

Avatrombopag improves thrombocytopenia in MYH9-related disorder following eltrombopag treatment failure

open access: yesPlatelets, 2022
MYH9-related disorder (MYH9-RD) is autosomal dominant thrombocytopenia caused by mutations in the MYH9 gene, which codes for the non-muscle myosin-IIA heavy chain. We present a case of a 24-year-old Chinese man with MYH9-RD who was initially misdiagnosed
Abdul Rehman Arif   +5 more
doaj   +1 more source

Differential expression of exosomal microRNAs in fresh and senescent apheresis platelet concentrates

open access: yesPlatelets, 2022
Patients have a high risk of suffering adverse reactions after receiving platelet products stored for 5 days. Bioactive exosomes in platelet products can be accumulated during storage, which is associated with adverse reactions.
Ziyue Mi   +7 more
doaj   +1 more source

Platelets and viruses

open access: yesPlatelets, 2021
Platelets play an essential role in maintaining vascular integrity after injury. In addition, platelets contribute to the immune response to pathogens. For instance, they express receptors that mediate binding of viruses, and toll-like receptors that activate the cell in response to pathogen-associated molecular patterns.
Silvio Antoniak, Nigel Mackman
openaire   +4 more sources

Sex-specific relationship between blood selenium levels and platelet count in a large cohort representative of the United States population

open access: yesPlatelets, 2022
While several small studies have found that selenium deficiency is associated with low platelet counts, they lack generalizability. We used data from the National Health and Nutrition Examination Surveys collected over a 12-year period.
Neda Rehan, Rehan Qayyum
doaj   +1 more source

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