Results 11 to 20 of about 1,117,967 (288)
Therapeutic potential of adult platelets and cord blood platelets in future clinical directions
Journal of Medical and Scientific Research, 2023 Platelet rich plasma (PRP) is currently obtaining a natural concentration of autologous growth factors, and is used in different medical conditions. This review is aimed to establish several treatment options using adult PRP and scope of the therapeutic ...
Bezawada SR, Velluri V, Darapuneni RC
doaj +1 more source
Humanized mouse models for inherited thrombocytopenia studies
Platelets, 2023 Inherited thrombocytopenia (IT) is a group of hereditary disorders characterized by a reduced platelet count as the main clinical manifestation, and often with abnormal platelet function, which can subsequently lead to impaired hemostasis.
Xiaojie Wang +13 more
doaj +1 more source
Circulating microRNAs as biomarkers and mediators of platelet activation
Platelets, 2022 Platelets are essential mediators of physiological hemostasis and pathological thrombosis. Currently available tests and markers of platelet activation did not prove successful in guiding treatment decisions for patients with cardiovascular disease ...
Clemens Gutmann, Manuel Mayr
doaj +1 more source
Platelets, 2022 Immune thrombocytopenia (ITP) is a condition that is distinct from thrombosis with thrombocytopenia syndrome (TTS) that may also occur after coronavirus disease 2019 (COVID-19) vaccinations.
Sheng-Chieh Chou +6 more
doaj +1 more source
The utility of flow cytometric platelet forward scatter as an alternative to mean platelet volume
Platelets, 2022 The use of mean platelet diameter (MPD) to classify inherited thrombocytopenia (IT) has been demonstrated in several studies. Alternatively, the mean platelet volume (MPV) may be used, but in macrothrombocytopenia this may not be available.
David Connor +12 more
doaj +1 more source
Platelets, 2022 MicroRNAs (miRNAs) are small, non-coding RNAs, able to regulate cellular functions by induction of mRNA degradation and post-transcriptional repression of gene expression.
Zofia Wicik +9 more
doaj +1 more source
Platelets Can Associate With SARS-CoV-2 RNA and Are Hyperactivated in COVID-19
Circulation Research, 2020 Supplemental Digital Content is available in the text. Rationale: In addition to the overwhelming lung inflammation that prevails in coronavirus disease 2019 (COVID-19), hypercoagulation and thrombosis contribute to the lethality of subjects infected ...
Y. Zaid +19 more
semanticscholar +1 more source
Platelets, 2022 Impaired platelet production is a mechanism of immune thrombocytopenia (ITP). Morphological abnormalities of megakaryocytes (MKs) are sometimes observed in this disease.
Ondine Walter +15 more
doaj +1 more source
Platelets, 2022 Platelets play important roles in thrombosis, hemostasis, inflammation, and infection. We aimed to evaluate the association between platelet count and its variation trend and prognosis of patient with infectious diseases in intensive care units (ICUs ...
Jiamei Li +13 more
doaj +1 more source
Platelets, 2022 In flow cytometry, individual cells are investigated. Platelet activation is normally reported in form of percentage of platelets expressing the marker (positive platelets) and/or mean/median fluorescence intensity (MFI) for the entire analyzed ...
Nahreen Tynngård +3 more
doaj +1 more source