Results 11 to 20 of about 527,915 (318)

BLOOD PLATELETS AS ACTIVATORS AND REGULATORS OF INFLAMMATORY AND IMMUNE REACTIONS. PART 1. BASIC CHARACTERISTICS OF PLATELETS AS INFLAMMATORY CELLS

open access: yesМедицинская иммунология, 2018
Platelets are the smallest blood cells, and yet their total volume and surface area exceed those of all types of leukocytes combined. Platelets are produced by the bone marrow megakaryocytes and megakaryocytes in the lung microvessels.
N. B. Serebryanaya   +3 more
doaj   +1 more source

Platelet index on admission as a predictor of bacteremia in acute cholangitis: a 7-year retrospective observational study

open access: yesPlatelets, 2022
Bacteremia frequently occurs in patients with acute cholangitis, which could increase the risk of mortality. This single-center retrospective observational study was conducted from July 2013 to July 2020 to evaluate the predictive value of platelet index
XiaoYing Chen   +3 more
doaj   +1 more source

Protocol for Murine/Mouse Platelets Isolation and Their Reintroduction in vivo

open access: yesBio-Protocol, 2017
Platelets and coagulation have long been known to be essential for metastasis in experimental models. In order to study the interactions between tumor cells, platelets and endothelium, we have adapted methods used in coagulation research for the ...
Jae Im, Ruth Muschel
doaj   +1 more source

Assessment of neonatal, cord, and adult platelet granule trafficking and secretion

open access: yesPlatelets, 2020
Despite the transient hyporeactivity of neonatal platelets, full-term neonates do not display a bleeding tendency, suggesting potential compensatory mechanisms which allow for balanced and efficient neonatal hemostasis.
Anh T. P. Ngo   +12 more
doaj   +1 more source

Effects of exercise on platelet reactivity after myocardial infarction: a randomized clinical trial

open access: yesPlatelets, 2022
Exercise training (ET) can lower platelet reactivity in patients with cardiovascular risk factors. However, the effects of ET on platelet reactivity in higher-risk patients is unknown.
Talia Falcão Dalçóquio   +14 more
doaj   +1 more source

Roles of non-coding RNA in megakaryocytopoiesis and thrombopoiesis: new target therapies in ITP

open access: yesPlatelets, 2023
Noncoding RNAs (ncRNAs) are a group of RNA molecules that cannot encode proteins, and a better understanding of the complex interaction networks coordinated by ncRNAs will provide a theoretical basis for the development of therapeutics targeting the ...
Wuquan Li, Yan Lv, Yeying Sun
doaj   +1 more source

Apoptosis is one cause of thrombocytopenia in patients with high-altitude polycythemia

open access: yesPlatelets, 2023
High-altitude polycythemia (HAPC) can occur in individuals who are intolerant to high-altitude hypoxia. In patients with HAPC, erythrocytosis is often accompanied by a decrease in platelet count.
Zhuoya Wang   +7 more
doaj   +1 more source

Treatment inequity in antiplatelet therapy for ischaemic heart disease in patients with advanced chronic kidney disease: releasing the evidence vacuum

open access: yesPlatelets, 2023
Chronic kidney disease (CKD) is a global health problem and an independent risk factor for cardiovascular morbidity and mortality. Despite evidence-based therapies significantly improving cardiovascular mortality outcomes in the general population and ...
Frances L. Varian   +3 more
doaj   +1 more source

Analysis of adenoviral attachment to human platelets

open access: yesVirology Journal, 2009
Background Systemic adenoviral (Ad) vector administration is associated with thrombocytopenia. Recently, Ad interaction with mouse platelets emerged as a key player determining liver uptake and platelet clearance.
Urieli-Shoval Simcha   +5 more
doaj   +1 more source

The CalDAG-GEFI/Rap1/αIIbβ3 axis minimally contributes to accelerated platelet clearance in mice with constitutive store-operated calcium entry

open access: yesPlatelets, 2023
Circulating platelets maintain low cytosolic Ca2+ concentrations. At sites of vascular injury, agonist-induced Ca2+ release from platelet intracellular stores triggers influx of extracellular Ca2+, a process known as store-operated Ca2+ entry (SOCE ...
Robert H. Lee   +3 more
doaj   +1 more source

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