Results 21 to 30 of about 638,324 (358)
Platelets, 2023 Circulating platelets maintain low cytosolic Ca2+ concentrations. At sites of vascular injury, agonist-induced Ca2+ release from platelet intracellular stores triggers influx of extracellular Ca2+, a process known as store-operated Ca2+ entry (SOCE ...
Robert H. Lee +3 more
doaj +1 more source
Evaluation of human platelet granules by structured illumination laser fluorescence microscopy
Platelets, 2023 Many roles of human platelets in health and disease are linked to their ability to transport and secrete a variety of small molecules and proteins carried in dense (δ-) and α-granules.
Fred G. Pluthero, Walter H. A. Kahr
doaj +1 more source
Platelet kinetics in the pulmonary microcirculation in vivo assessed by intravital microscopy [PDF]
, 2002 Growing evidence supports the substantial pathophysiological impact of platelets on the development of acute lung injury. Methods for studying these cellular mechanisms in vivo are not present yet.
Eichhorn, M. E. +3 more
core +1 more source
Developing human tissue engineered arterial constructs to simulate human in vivo thrombus formation
Platelets, 2023 Thrombus formation is highly dependent upon the physico-chemical environment in which it is triggered. Our ability to understand how thrombus formation is initiated, regulated, and resolved in the human body is dependent upon our ability to replicate the
Jacob Ranjbar +2 more
doaj +1 more source
Platelets and Anti-platelet Therapy
Journal of Pharmacological Sciences, 2003 Platelets play a central role in the hemostatic process and consequently are similarly involved in the pathological counterpart, thrombosis. They adhere to various subendothelial proteins, exposed either by injury or disease, and subsequently become activated by the thrombogenic surface or locally produced agonists.
Sara J. Israels, Archibald McNicol
openaire +5 more sources
Association of immature platelets with perioperative complications in neurosurgery
Platelets, 2023 Immature platelets are newly formed platelets with an increased prothrombotic potential. This study evaluates whether immature platelets are associated with relevant complications in neurosurgical patients.
Aida Anetsberger +10 more
doaj +1 more source
Role of P-selectin in platelet sequestration in pulmonary capillaries during endotoxemia [PDF]
, 2006 Background: There is growing evidence that platelets accumulate in the lung and contribute to the pathogenesis of acute lung injury during endotoxemia.
Alwin Eduard Goetz +37 more
core +1 more source
Immature platelets in COVID-19
Platelets, 2023 Platelets play a critical role in immune response. Coronavirus disease 2019 (COVID-19) patients with a severe course often show pathological coagulation parameters including thrombocytopenia, and at the same time the proportion of immature platelets ...
Monika Wolny +3 more
doaj +1 more source
Immersed boundary simulations of cell-cell interactions in whole blood [PDF]
, 2021 We present a new method for the geometric reconstruction of elastic surfaces simulated by the immersed boundary method with the goal of simulating the motion and interactions of cells in whole blood. Our method uses parameter-free radial basis functions for high-order meshless parametric reconstruction of point clouds and the elastic force computations
arxiv +1 more source
An in vitro study of the adhesion of blood platelets onto vascular catheters. Part I [PDF]
, 1987 The adhesion of human blood platelets onto vascular catheters was studied using a specially designed perfusion chamber. Polyurethane catheters were exposed to citrated human blood for different periods (up to 20 min) and at different wall shear rates ...
Aarts, P.A.M.M. +5 more
core +3 more sources