Results 21 to 30 of about 703,101 (336)

Association of platelet count with mortality in patients with infectious diseases in intensive care unit: a multicenter retrospective cohort study

Platelets, 2022
Platelets play important roles in thrombosis, hemostasis, inflammation, and infection. We aimed to evaluate the association between platelet count and its variation trend and prognosis of patient with infectious diseases in intensive care units (ICUs ...
Jiamei Li, Ruohan Li, Xuting Jin, Jiajia Ren, Linyun Du, Jingjing Zhang, Ya Gao, Xiu Liu, Yanli Hou, Lei Zhang, Zhenju Song, Jingchun Song, Xiaochuang Wang, Gang Wang   +13 more
doaj   +1 more source

Variation in activation marker expression within the platelet population – a new parameter for evaluation of platelet flow cytometry data

Platelets, 2022
In flow cytometry, individual cells are investigated. Platelet activation is normally reported in form of percentage of platelets expressing the marker (positive platelets) and/or mean/median fluorescence intensity (MFI) for the entire analyzed ...
Nahreen Tynngård, Aseel Alshamari, Freja Månsson, Sofia Ramström   +3 more
doaj   +1 more source

Evidence for a PI3-kinase independent pathway in the regulation of Rap1b activation downstream of the P2Y12 receptor in platelets

Platelets, 2022
Platelet activation by adenosine diphosphate (ADP) is mediated through two G-protein-coupled receptors, P2Y1 and P2Y12, which signal through Gq and Gi, respectively.
Carol Dangelmaier, Satya P Kunapuli
doaj   +1 more source

Avatrombopag improves thrombocytopenia in MYH9-related disorder following eltrombopag treatment failure

Platelets, 2022
MYH9-related disorder (MYH9-RD) is autosomal dominant thrombocytopenia caused by mutations in the MYH9 gene, which codes for the non-muscle myosin-IIA heavy chain. We present a case of a 24-year-old Chinese man with MYH9-RD who was initially misdiagnosed
Abdul Rehman Arif, Miaomiao Zhao, Wenlan Chen, Mei Xue, Shanshan Luo, Yadan Wang   +5 more
doaj   +1 more source

Differential expression of exosomal microRNAs in fresh and senescent apheresis platelet concentrates

Platelets, 2022
Patients have a high risk of suffering adverse reactions after receiving platelet products stored for 5 days. Bioactive exosomes in platelet products can be accumulated during storage, which is associated with adverse reactions.
Ziyue Mi, Li Gong, Yujie Kong, Peizhe Zhao, Yonghua Yin, Haixia Xu, Li Tian, Zhong Liu   +7 more
doaj   +1 more source

Sex-specific relationship between blood selenium levels and platelet count in a large cohort representative of the United States population

Platelets, 2022
While several small studies have found that selenium deficiency is associated with low platelet counts, they lack generalizability. We used data from the National Health and Nutrition Examination Surveys collected over a 12-year period.
Neda Rehan, Rehan Qayyum
doaj   +1 more source

Gender-related differences in changes of estimated bleeding risk in patients on dual antiplatelet therapy: the RE-SCORE multicenter prospective registry

Platelets, 2022
The risk of bleeding as predicted by the PRECISE-DAPT score can vary over time after percutaneous coronary intervention (PCI). We sought to compare the predictive ability of the PRECISE-DAPT score calculated at baseline and reassessed during follow-up in
Francesco Pelliccia, Felice Gragnano, Vincenzo Pasceri, Giuseppe Marazzi, Luca Cacciotti, Attilio Placanica, Giampaolo Niccoli, Tullio Palmerini, Giulio Speciale, Antonino Granatelli, Paolo Calabrò   +10 more
doaj   +1 more source

Platelet kinetics in the pulmonary microcirculation in vivo assessed by intravital microscopy [PDF]

, 2002
Growing evidence supports the substantial pathophysiological impact of platelets on the development of acute lung injury. Methods for studying these cellular mechanisms in vivo are not present yet.
Eichhorn, M. E., Goetz, Alwin Eduard, Massberg, S., Ney, L.   +3 more
core   +1 more source

Diagnostic and prognostic role of platelets in patients with sepsis and septic shock

Platelets, 2023
Studies investigating the prognostic role of platelets commonly include critically ill patients, whereas data regarding the prognostic impact of platelet count in patients admitted with sepsis and septic shock is limited.
Tobias Schupp, Kathrin Weidner, Jonas Rusnak, Schanas Jawhar, Jan Forner, Floriana Dulatahu, Lea Marie Brück, Ursula Hoffmann, Maximilian Kittel, Thomas Bertsch, Ibrahim Akin, Michael Behnes   +11 more
doaj   +1 more source

Role of P-selectin in platelet sequestration in pulmonary capillaries during endotoxemia [PDF]

, 2006
Background: There is growing evidence that platelets accumulate in the lung and contribute to the pathogenesis of acute lung injury during endotoxemia.
Alwin Eduard Goetz, Barry BE, Bevilacqua MP, Body SC, Brunk DK, Deuel TF, Dore M, Feuerhake F, Forde RC, Frenette PS, Greenberg AW, Handa K, Hattori R, Heffner JE, Kai Heckel, Kiefmann R, Kubes P, Kubo H, Kuebler WM, Kuhnle GE, Kuhnle GE, Kuklin V, Leo R, Ley K, Li N, Martina Dörger, Massberg S, Matsui NM, Okada Y, Parish CR, Piccardoni P, Rainer Kiefmann, Rinko LJ, Rodgers SD, Ruf A, Sonja Schenkat, Wang L, Williams MJ   +37 more
core   +1 more source