Results 51 to 60 of about 638,324 (358)

Severe thrombocytopenia and intracranial hemorrhage in a newborn with Noonan syndrome and neonatal alloimmune thrombocytopenia

Platelets, 2022
Noonan syndrome (NS) is a genetic disorder with distinctive physical features and often multiple organ involvement. Bleeding disorders are reported in over half of patients with NS, including thrombocytopenia and platelet dysfunction. Neonatal alloimmune
Rebecca Carter, Anna-Kaisa Niemi
doaj   +1 more source

The trans-sialidase from Trypanosoma cruzi induces thrombocytopenia during acute Chagas' disease by reducing the platelet sialic acid contents [PDF]

, 2005
Strong thrombocytopenia is observed during acute infection with Trypanosoma cruzi, the parasitic protozoan agent of American trypanosomiasis or Chagas' disease.
Campetella, O., Leguizamon, M.S., Mucci, J., Rooijen, N. van, Tribulatti, M.V.   +4 more
core   +2 more sources

Performance of the REACH, PARIS, BleeMACS, and PRECISE-DAPT scores for predicting 1-year bleeding events in patients undergoing coronary drug-eluting stent implantation

Platelets, 2022
This study aimed to evaluate the predictive performance of the REACH, PARIS, BleeMACS, and PRECISE-DAPT scores in Chinese patients undergoing coronary drug-eluting stent (DES) implantation.
Si-Qi Lyu, Jun Zhu, Juan Wang, Shuang Wu, Han Zhang, Xing-Hui Shao, Yan-min Yang   +6 more
doaj   +1 more source

Bulk fluid phase behaviour of colloidal platelet-sphere and platelet-polymer mixtures [PDF]

, 2012
Using a geometry-based fundamental measure density functional theory, we calculate bulk fluid phase diagrams of colloidal mixtures of vanishingly thin hard circular platelets and hard spheres. We find isotropic-nematic phase separation with strong broadening of the biphasic region upon increasing the pressure.
arxiv   +1 more source

Glycoprotein Ib activation by thrombin stimulates the energy metabolism in human platelets [PDF]

, 2017
Thrombin-induced platelet activation requires substantial amounts of ATP. However, the specific contribution of each ATP-generating pathway i.e., oxidative phosphorylation (OxPhos) versus glycolysis and the biochemical mechanisms involved in the thrombin-
A Archiche, A Ferreta, A Kasirer-Friede, A Lechi, A Marín-Hernández, AI Schafer, AJM Verhoeven, AM Amorini, AN Sveshnikova, AR Gear, Christian Schulz, D Banerjee, DA Slatter, E De Candia, E De Candia, F Adam, F Sinigaglia, G Solsau, GN Bijur, H Kilkson, HU Bergmeyer, I Fisher, I Hernández-Reséndiz, Ileana Hernández-Reséndiz, J Deprez, JRS Day, JW Akkerman, JY Jang, KS Authi, L Brass, LR Sorbara, M Baggiolini, Manuel Gutiérrez-Aguilar, MH Rider, MR Wardell, MY Shen, N Cardenes, N Corona de la Peña, NM Bressler, Norma Corona de la Peña, RA Nakashima, RL Elstrom, RM Denton, RW Moreadith, S Kim, S Offermans, S Ravi, S Rodríguez-Enríquez, S Zharikov, Sara Rodríguez-Enríquez, SI Obydennyy, T Sabo, V Vasta, Y Dobrydneva, Y Dobrydneva, ZP Shaik, Álvaro Marín-Hernández   +56 more
core   +3 more sources

Platelets and viruses

Platelets, 2021
Platelets play an essential role in maintaining vascular integrity after injury. In addition, platelets contribute to the immune response to pathogens. For instance, they express receptors that mediate binding of viruses, and toll-like receptors that activate the cell in response to pathogen-associated molecular patterns.
Silvio Antoniak, Nigel Mackman
openaire   +4 more sources

“Tailored” antiplatelet bridging therapy with cangrelor: moving toward personalized medicine

Platelets, 2022
In the setting of patients with indication to receive dual antiplatelet therapy undergoing surgery or invasive procedures, the risk of perioperative cardiac ischemic events, particularly stent thrombosis, is high, because surgery has a prothrombotic ...
Renato Valenti, Iacopo Muraca, Rossella Marcucci, Francesca Ciatti, Martina Berteotti, Anna Maria Gori, Nazario Carrabba, Angela Migliorini, Niccolò Marchionni, Marco Valgimigli   +9 more
doaj   +1 more source

The tyrosine phosphatase CD148 is an essential positive regulator of platelet activation and thrombosis [PDF]

, 2009
Platelets play a fundamental role in hemostasis and thrombosis. They are also involved in pathologic conditions resulting from blocked blood vessels, including myocardial infarction and ischemic stroke.
Abtahian, Alexandra Mazharian, Arias-Salgado, Arias-Salgado, Arthur Weiss, Asselin, Auger, Avecilla, Baker, Best, Best, Cheli, Choudhuri, Dhanjal, Dorahy, Dubois, Ezumi, Gibbins, Gibbins, Harper, Hermiston, Holsinger, Jenson Lim, Jing W. Zhu, Jocelyn M. Auger, Kalia, Kato, Klages, Kovalenko, Kralisz, Kristin N. Kornerup, Le Pera, Lin, Lin, Liu, Mangin, McCarty, McNeill, Michael G. Tomlinson, Minuz, Moarefi, Mocsai, Morton, Neena Kalia, Nonne, Obergfell, Palka, Park, Pasquet, Pasquet, Pasquet, Pearce, Poole, Quek, Senis, Snell, Somani, Sorby, Steve G. Thomas, Steve P. Watson, Stuart Ellison, Superti-Furga, Suzuki-Inoue, Suzuki-Inoue, Tarvinder Dhanjal, Tsuboi, Vandendries, Wagner, Watanabe, Watson, Wonerow, Woodside, Xu, Xu, Yamaguchi, Yan Zhao, Yotis A. Senis, Young, Zhang, Zhu   +79 more
core   +2 more sources

Report of clinical presentations and two novel mutations in patients with Wiskott-Aldrich syndrome/X-linked Thrombocytopenia

Platelets, 2022
Wiskott-Aldrich syndrome (WAS)/X-linked thrombocytopenia (XLT) is a rare X-linked disease characterized by thrombocytopenia, eczema, and recurrent infection. In addition, WAS/XLT increases incidence of autoimmune diseases and malignancies.
Natsumon Udomkittivorakul, Duangrurdee Wattanasirichaigoon, Wiparat Manuyakorn, Pongpak Pongphitcha, Arthaporn Khongkraparn, Padcha Tunlayadechanont, Nongnuch Sirachainan   +6 more
doaj   +1 more source

Immunoregulatory mechanisms of the arachidonic acid pathway in cancer

FEBS Letters, EarlyView.
The central role of the arachidonic acid (AA) pathway in anticancer immunity. Enzymes and metabolites of the AA pathway can play both immunosuppressive and immunostimulatory roles in the tumor microenvironment. Therefore, their tailored targeting could be beneficial as a standalone therapy or in combination with current cancer immunotherapy.
Maria Tredicine, Matteo Mucci, Antonio Recchiuti, Domenico Mattoscio   +3 more
wiley   +1 more source