Results 71 to 80 of about 527,915 (318)

Endocytic Programming via Porous Silicon Nanoparticles Enhances TLR4 Nanoagonist Potency for Macrophage‐Mediated Immunotherapy

Advanced Functional Materials, EarlyView.
Porous silicon nanoparticles (PSiNPs) reprogram macrophage endocytosis of manganese@albumin‐based TLR4 nanoagonists, driving TRIF‐biased TLR4 signaling, eliciting robust proinflammatory responses, and potentiating macrophage‐mediated immunotherapeutic effects against NSCLC.
Xiaomei Zhang, Huiying Li, Shuodan Huang, Linxuan Zhang, Yan Gao, Ruoran Wang, Xiaoyu Wang, Hélder A. Santos, Zhenyu Yin, Bing Xia   +9 more
wiley   +1 more source

Synergistic Osteogenesis After Co‐Administration of cmRNAs Encoding BMP‐2 and BMP‐7 Utilizing a Transcript‐Activated Matrix

Advanced Functional Materials, EarlyView.
This study demonstrates that the dual delivery of BMP‐2/‐7 coding cmRNAs for bone healing is demonstrated as feasible, safe, and highly osteogenic. Compared to single BMP‐2 or BMP‐7 cmRNAs, the combination enhances the production of both mineral and organic components of the extracellular matrix when delivered using a collagen‐HA scaffold, supporting ...
Claudia Del Toro Runzer, Joanna M. Sadowska, Nadia Roumans, Christian Plank, Christopher H. Evans, Fergal J. O'Brien, Martijn van Griensven, Elizabeth R. Balmayor   +7 more
wiley   +1 more source

A Self‐Curling Si3N4‐Biofunctionalized Nerve Wrap for Suture‐Free Peripheral Nerve Repair with Multimodal Regenerative Bioregulation

Advanced Functional Materials, EarlyView.
Si3N4‐enhanced bioactive nanostructured adhesive wrap enables rapid conduit formation in wet environments, simplifying surgical procedures. Incorporated Si3N4 undergoes controlled hydrolysis within nanofibers, multi‐directionally modulating the peripheral nerve repair microenvironment for effective suture‐free repair.
Pengchao Ma, Yihao Liu, Bowen Ren, Chun‐Yi Yang, Xiaobin Luo, Peilun Hu, Jia Yang, Zheng Cao, Keya Mao, Jianheng Liu, Xiumei Wang   +10 more
wiley   +1 more source

Design and Applications of Multi‐Frequency Programmable Metamaterials for Adaptive Stealth

Advanced Functional Materials, EarlyView.
This article provides a comprehensive overview of metamaterials, including their fundamental principles, properties, synthesis techniques, and applications in stealth, as well as their challenges and future prospects. It covers topics that are more advanced than those typically discussed in existing review articles, while still being closely connected ...
Jonathan Tersur Orasugh, Ankita Mohanty, Amit Malakar, Suryasarathi Bose, Suprakas Sinha Ray   +4 more
wiley   +1 more source

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source

Emerging 2D Materials and Their Hybrid Nanostructures for Label‐Free Optical Biosensing: Recent Progress and Outlook

Advanced Functional Materials, EarlyView.
This review highlights recent advances in label‐free optical biosensors based on 2D materials and rationally designed mixed‐dimensional nanohybrids, emphasizing their synergistic effects and novel functionalities. It also discusses multifunctional sensing platforms and the integration of machine learning for intelligent data analysis.
Xinyi Li, Yonghao Fu, Yuehe Lin, Dan Du
wiley   +1 more source

Platelet receptors: An instrumental of platelet physiology

Pakistan Journal of Medical Sciences, 2013
Platelets play an important role in hemostasis, inflammation, host defense, tumor growth and metastasis. Platelets receptors are instrumental in platelet-platelet aggregation and interaction of platelets with leukocytes, endothelial cells and coagulation factors. These receptors are also the targets for antiplatelet drugs.
Muhammad, Saboor, Qamar, Ayub, Samina, Ilyas, , Moinuddin   +3 more
openaire   +2 more sources

Ion and Solvent Dynamics in Charged 2D Clay Nanoslits with Unprecedented Ångström‐Precise Slit Height Control

Advanced Functional Materials, EarlyView.
The slit height of fluorohectorite 2D‐nanochannels is tuned with Å‐precision (2.4–250 Å). Slit‐height‐dependent ion and water mobilities are quantified by applying EIS, PFG‐NMR, and SFG‐NMR with MD simulations guiding interpretation. Diffuse properties are investigated with CP‐AFM, MD, and PB.
Max Stevenson, Sandra Pappler, Leonie Kanzler, Aqsa Nisar, Jepsinraj Kakkuzhiyulla Parambath, Markus Rosenstihl, Flora Lebeda, Sebastian Weiß, Georg Papastavrou, Michael Vogel, Jürgen Senker, Josef Breu   +11 more
wiley   +1 more source

Inducing Chirality and Chiral Instabilities in Ferrogels with Homogenous Magnetic Fields

Advanced Functional Materials, EarlyView.
By pre‐aligning magnetic particles into chains, significant chiral deformations are induced by fixing the base of a cylindrical actuator and applying a homogeneous magnetic field. Subsequent base rotation can drive the system into metastable states. Further rotation or reduction of field strength triggers a chiral instability, characterized by a switch
Francisco J. Vazquez‐Perez, Alberto Leon‐Cecilla, Luis Álvarez de Cienfuegos, James E. Martin, Modesto T. Lopez‐Lopez   +4 more
wiley   +1 more source

The Role of Platelet-Derived Extracellular Vesicles in Immune-Mediated Thrombosis [PDF]

, 2022
Alicia S. Eustes, Sanjana Dayal
openalex   +1 more source