Results 51 to 60 of about 463,872 (313)

The periodontal pathogen Porphyromonas gingivalis sensitises human blood platelets to epinephrine

, 2008
Recent studies indicate connections between periodontitis and atherothrombosis, and the periodontal pathogen Porphyromonas gingivalis has been found within atherosclerotic lesions. P.
Lindahl, Tomas L.,, Nylander, M,, Grenegård, M,, Bengtsson, Torbjörn,, Grenegård, Magnus,, Lindahl, T L,, Nylander, Martina,   +6 more
core   +1 more source

Immunological platelet transfusion refractoriness: current insights from mechanisms to therapeutics

Platelets
Although there have been tremendous improvements in the production and storage of platelets, platelet transfusion refractoriness (PTR) remains a serious clinical issue that may lead to various severe adverse events.
Xiaoyu Chen, Yuhong Zhao, Yan Lv, Jue Xie   +3 more
doaj   +1 more source

Effects of platelet-rich fibrin produced by three centrifugation protocols on bone neoformation in defects created in rat calvaria

Platelets, 2023
This study evaluated the potential of Leukocyte-platelet-rich fibrin (L-PRF; fixed angle centrifugation protocol), Advanced-platelet-rich fibrin (A-PRF; low-speed fixed angle centrifugation protocol), and Horizontal-platelet-rich fibrin (H-PRF ...
Débora de Souza Ferreira Sávio, Lucia Moitrel Pequeno da Silva, Gabriel Guerra David Reis, Ricardo Junior Denardi, Natacha Malu Miranda da Costa, Flávia Aparecida Chaves Furlaneto, Sérgio Luís Scombatti de Souza, Carlos Fernando de Almeida Barros Mourão, Richard J. Miron, Roberta Okamoto, Michel Reis Messora   +10 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Phosphorylation of (Ser 291) in the linker insert of Syk negatively regulates ITAM signaling in platelets

Platelets
Receptor-induced tyrosine phosphorylation of spleen tyrosine kinase (Syk) has been studied extensively in hematopoietic cells. Metabolic mapping and high-resolution mass spectrometry, however, indicate that one of the most frequently detected ...
Carol Dangelmaier, Hymavathi Reddy Vari, Dhruv N Vajipayajula, Manal Elzoheiry, Monica Wright, Ashvin Iyer, Alexander Y Tsygankov, Satya P Kunapuli   +7 more
doaj   +1 more source

Neonatal platelet physiology and implications for transfusion

Platelets, 2022
The neonatal hemostatic system is different from that of adults. The differences in levels of procoagulant and anticoagulant factors and the evolving equilibrium in secondary hemostasis during the transition from fetal/neonatal life to infancy, childhood,
Francisca Ferrer-Marín, Martha Sola-Visner   +1 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Platelets and acute cerebral infarction

, 2013
Stroke is worldwide a leading cause of death and disability. Its etiology is regarded as heterogeneous. Platelets are implicated in its pathophysiology, but our understanding of their specific role is incomplete.
Eriksson, M., Nilsson, Staffan, Milovanovic, Micha,, Milovanovic, Micha, Lindahl, Tomas,, Nilsson, Staffan,, Eriksson, M.,, Järemo, Petter,, Järemo, Petter, Lindahl, Tomas   +9 more
core   +1 more source

Role of P-selectin in platelet sequestration in pulmonary capillaries during endotoxemia [PDF]

, 2006
Background: There is growing evidence that platelets accumulate in the lung and contribute to the pathogenesis of acute lung injury during endotoxemia.
Schenkat, Sonja, Kiefmann, Rainer, Dörger, Martina, Goetz, Alwin Eduard, Heckel, Kai   +4 more
core   +1 more source

Distinguishing Pathological from Physiological Activation of Platelets Potentiated by Exercise

, 2023
Background: Exercise is widely accepted to exert beneficial effect on human health in prevention and treatment of cardiovascular diseases (CVD). However, a paradox has emerged where exercise has been documented to result in pathological activation of ...
Jurcevic, S., Dishkelov, A., Elliott, B., Rashvand, S.   +3 more
core   +3 more sources