Results 101 to 110 of about 3,387,841 (331)

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

THE BUCKLING ANALYSIS OF A RECTANGULAR PLATE ELASTICALLY CLAMPED ALONG THE LONGITUDINAL EDGES

Applied Engineering Letters, 2016
The paper analyses the stability of a rectangular plate which is elastically buckled along longitudinal edges and pressed by equally distributed forces. A general case is analyzed – different stiffness elastic clamping and then special simpler cases are ...
Ivan Miletić, Marko Miletić
doaj  

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Incompatible Deformations in Hyperelastic Plates

Mathematics
The design of thin-walled structures is commonly based on the solutions of linear boundary-value problems, formulated within well-developed theories for elastic plates and shells.
Sergey Lychev, Alexander Digilov, Vladimir Bespalov, Nikolay Djuzhev   +3 more
doaj   +1 more source

Automatic thermal switch [PDF]

, 1981
An automatic thermal switch to control heat flow includes a first thermally conductive plate, a second thermally conductive plate and a thermal transfer plate pivotally mounted between the first and second plates.
Cunningham, J. W., Wing, L. D.
core   +1 more source

No quantum friction between uniformly moving plates

, 2009
The Casimir forces between two plates moving parallel to each other are found by calculating the vacuum electromagnetic stress tensor. The perpendicular force between the plates is modified by the motion but there is no lateral force on the plates ...
Leonhardt, U., Philbin, T. G.
core   +2 more sources

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Geothermal Casimir Phenomena

, 2008
We present first worldline analytical and numerical results for the nontrivial interplay between geometry and temperature dependencies of the Casimir effect.
Brevik I Ellingsen S A Milton K A, Casimir H B G, Emig T Graham N Jaffe R L Kardar M, Emig T Graham N Jaffe R L Kardar M, Gies H, Gies H, Holger Gies, Klaus Klingmüller, Klingmuller K, Mazzitelli F D, Milton K A, Mostepanenko V M, Wirzba A   +12 more
core   +1 more source

Antibacterial effects of protruding and recessed shark skin micropatterned surfaces of polyacrylate plate with a shallow groove [PDF]

, 2014
Akihiko Sakamoto, Yusuke Terui, Chihiro Horie, Takashi Fukui, Toshiyuki Masuzawa, Shintaro Sugawara, Kaku Shigeta, Tatsuo Shigeta, Kazuei Igarashi, Keiko Kashiwagi   +9 more
openalex   +1 more source