Results 31 to 40 of about 203,750 (253)
Optimisation of timber platform frame construction [PDF]
, 2007 Timber platform frame has evolved as an efficient method of construction for domestic dwellings and is experiencing continual growth in the UK due to it lending itself to off-site modem methods of construction (MMC), being environmentally efficient and exhibiting structural robustness.
openaire +1 more source
Disruption, Embedded. A Polanyian Framing of the Platform Economy
Sociologica, 2020 Sociologica, Vol 14, No 1 (2020)
Grabher, Gernot, König, Jonas
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Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Buildings, 2023 Based on a practical engineering case of seismic strengthening, this paper used the enlarging cross-section method and an external self-centering substructure to improve the seismic performance and seismic resilience of existing frame structures.
Weiheng Liu +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Key Technology of Construction Process Control of Guide Frame Platform Suction Bucket Foundation
南方能源建设, 2023 [Introduction] The present, design and construction technology of suction bucket foundation is not mature, and there is lack of the normative guidance documents, the special research on the key technology of the construction process control of the ...
Huaquan LIU +4 more
doaj +1 more source
HPM-Frame: A Decision Framework for Executing Software on Heterogeneous Platforms
CoRR, 2020 Heterogeneous computing is one of the most important computational solutions to meet rapidly increasing demands on system performance. It typically allows the main flow of applications to be executed on a CPU while the most computationally intensive tasks are assigned to one or more accelerators, such as GPUs and FPGAs.
Hugo Sica de Andrade +4 more
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Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source