Results 101 to 110 of about 450,650 (277)
Six Challenges in Platform Licensing and Open Innovation [PDF]
This article describes six common challenges of design, incentives, and governance that arise in establishing platform businesses. It also proposes solutions.
Geoffrey PARKER, Marshall VAN ALSTYNE
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Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Newsletter / House of Finance, Goethe-Universität Frankfurt 4/09 [PDF]
, 2010 Editorial: Jens Weidmann : "Central Banks and Monetary Policy after the Crisis" Research Finance: Holger Kraft,Claus Munk : "Optimal Housing, Consumption, and Investment Decisions over the Life Cycle" Research Money/Macro: Ester Faia, Eleni Iliopulos ...
House of Finance
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Whorephobia on Dating Platforms: Ethical Platform Governance
Philosophy & TechnologyAbstract Dating platforms generally prohibit commercial sex on their platforms and warn users that they will be deplatformed if they engage in the sex market on them. Sex workers, however, report experiencing deplatforming even when they are seeking personal, non-commercial relationships on dating platforms, which raises complaints of
openaire +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Journalism and MediaThe Digital Services Act (DSA) is the first supranational regulation aimed at improving the safety, transparency and accountability of online platforms.
Matteo Fabbri
doaj +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Europe and China’s Belt and Road Initiative: Growing Concerns, More Strategy. Egmont Security Policy Brief No. 118 November 2019 [PDF]
, 2019 Geopolitical shifts are engendering a transformation of the globalized economic order that has flourished in the post-Cold War period. This trend runs deep and raises structural challenges, - such as the rivalry between different economic models, the ...
Geeraerts , Gustaaf
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International Journal of Cultural StudiesTo mediate the tensions between state regulation and content-creator incentives, Chinese social media platforms have developed an interesting practice of using platform official accounts to communicate their rules to the creator community. These accounts anthropomorphize platforms, enabling platforms to represent their regulatory bodies using ...
Zhen Ye, Qian Huang, Tonny Krijnen
openaire +2 more sources
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source