Results 61 to 70 of about 450,650 (277)

Governing online platforms: Competition policy in times of platformization [PDF]

Telecommunications Policy, 2018
Abstract This paper argues that a paradigmatic change in competition policy is needed and empirically under way to cope with the challenges posed by economically strong online platforms and their big-data-based business models. Competition policy needs to move further away from its traditional price-oriented emphasis and increasingly focus on non ...
openaire   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

From tweets to power: an integrative thematic review of political communication and platform governance on Twitter/X (2009–2024)

Frontiers in Political Science
IntroductionThis integrative thematic review synthesizes the body of peer-reviewed studies on political communication via Twitter/X, aiming to map the conceptual and methodological landscape of the field as indexed in major databases from the platform’s ...
Andrés Naranjo-Vinueza, Sonia Casillas-Martín, Marcos Cabezas-González, Pedro T. Nevado-Batalla Moreno   +3 more
doaj   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Platform Practice and Non-Discrimination

University of Vienna Law Review
Platforms have developed into important communicative facilities. Rules and practices of platforms define what happens on a platform, but these rules and practices are not free from discrimination.
Felicitas Rachinger
doaj   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Antecedents of Reporting Harmful Comments: Testing the Moderating Role of Perceived Transparency

International Journal of Communication
This study examines the antecedents of reporting harmful comments on the platform from a user’s perspective, focusing on perceived media effects. Although some research has examined the “report” or “flag” function as a sociotechnical apparatus for ...
Xinzhou Xie, Zhuo Song, Qiyu Bai
doaj   +2 more sources

Auditing cognitive drift in AI-driven recommendation: a responsible AI methods protocol with a health case demonstration

Frontiers in Neuroscience
We propose a protocol to detect and track cognitive drift caused by algorithmic curation. We confirm that the protocol is interpretable, sensitive, reproducible, and portable across domains.
Zhuowei Li, Congqian Zhu
doaj   +1 more source

Deepening democracy within Ireland's social partnership [PDF]

, 2009
Ireland's social partnership process, now under attack from a number of quarters, has repeatedly been charged with being 'undemocratic' in that it undermines the sovereign position of elected political representatives, with key policy formulation and ...
Allen K., Bang H. P., Benhabib S., Berlin I., Bogason P., Castells M., Cornwall A., Dean M., Fung A., Government of Ireland, Habermas J., Hastings T., Held D., Held D., Hirst P., Hulme D., Kirby P., Kooiman J., Lewis D., Macpherson C. B., Mansbridge J., March J. G., MEJN, Mouffe C., Murphy G., Murphy M., NESC, National Economic and Social Council, Newman J., Niamh Gaynor, Pearce J., Pierre J., Reddel T., Rosell S. A., Sørensen E., Tansey S. D., The Irish Times, Triantafillou P., Weber H., Ó Cinnéide S., Ó Cinnéide S.   +39 more
core   +1 more source