Results 41 to 50 of about 1,229,988 (286)
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Frontiers in SociologyDigital platforms have led to the emergence of a new digital proletariat worldwide, subject to institutional arrangements that put the labor framework outside of labor law.
José Soeiro +2 more
doaj +1 more source
A Call for Change: The Evolution of the Modern Documentary from Informative Media to Persuasive Platform [PDF]
, 2011 In the past several years, new documentaries have begun to evolve from informative media to persuasive platform as a result of changing cultural contexts and ideologies.
England, Valerie
core +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
European Journal of Risk RegulationIn two fields that are currently of high political salience and strategic significance – the regulation of digital platforms, and the regulation of environmental and human rights impacts in global value chains – the EU has taken a strikingly similar ...
Rachel Griffin, Riccardo Fornasari
doaj +1 more source
Cell Reports, 2017 Summary: Inflammatory bowel disease comprises a group of heterogeneous diseases characterized by chronic and relapsing mucosal inflammation. Alterations in microbiota composition have been proposed to contribute to disease development, but no uniform ...
Urmi Roy +9 more
doaj +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
European Journal of Risk RegulationAs part of its risk management system, aiming at the mitigation of so-called systemic risks on very large online platforms and very large online search engines (VLOPSEs), the DSA introduces data access rights for independent researchers.
Anna Liesenfeld +2 more
doaj +1 more source
Internet Policy Review, 2019 This article addresses the problem of platform power by probing current regulatory frameworks’ basic assumptions about how tech firms operate in digital ecosystems.
José van Dijck +2 more
doaj +1 more source
From brand safety to suitability: advertisers in platform governance
Internet Policy Review, 2023 Scholarship has long identified the business imperative to create an advertiser-friendly environment as a key influence on social media content moderation.
Rachel Griffin
doaj +1 more source