Results 31 to 40 of about 625,438 (268)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Platformization in Tourism: Typology of Business Models, Evolution of Market Concentration and European Regulation Responses

open access: yesPlatforms
The paper serves to discuss the evolution of platform business models in tourism, the dynamics of market concentration, and regulatory interventions. We present the historical timeline of digitalization in tourism distribution models, starting from the ...
Maja Turnšek, Vladimir Radivojević
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Platforms as Proximity Enablers for Regional Development

open access: yesPlatforms
This study offers a theoretical contribution exploring the interplay between platforms, proximity, and regional development and highlighting platforms’ crucial role in transforming routines and enhancing regional capabilities.
Anastasia Panori
doaj   +1 more source

What’s in a word? Platforms Supporting the Platform Economy

open access: yesProceedings of the 11th Nordic Conference on Human-Computer Interaction: Shaping Experiences, Shaping Society, 2020
This paper aspires to develop a deeper understanding of the sharing/collaborative/platform economy, and in particular of the technical mechanisms upon which the digital platforms supporting it are built. In surveying the research literature, the paper identifies a gap between studies from economical, social or socio-technical angles, and presentations ...
Bødker, Susanne   +2 more
openaire   +3 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

A Scalable Framework for Real-Time Network Security Traffic Analysis and Attack Detection Using Machine and Deep Learning

open access: yesPlatforms
This paper presents an advanced framework for real-time monitoring and analysis of network traffic and endpoint security in large-scale enterprises by addressing the increasing complexity and frequency of cyber-attacks.
Zineb Maasaoui   +3 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

The Role of the Platform Economy in Transforming Automotive Suppliers: A Case Study of the Northern Black Forest

open access: yesPlatforms
The European automotive industry, particularly in Germany, faces a significant crisis, heavily impacting suppliers reliant on OEMs. To enhance resilience, participation in the platform economy has been proposed as a solution.
Bernhard Kölmel   +5 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

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