Results 51 to 60 of about 1,337,565 (255)

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Open Versus Closed Platforms [PDF]

open access: yes
This paper studies an industry in which firms can choose to provide open or closed platforms. Open platforms, as opposed to closed, are extendable so third-party producers can develop extensions for them. Building on a two-sided market model, I show that
Tåg, Joacim
core  

Beyond Reality—How Are Virtual Reality and the Metaverse Shaping Tourism?

open access: yesPlatforms
This study aims to systematically analyze scholarly research on virtual reality (VR), augmented reality (AR), and the metaverse in the tourism and hospitality sectors, offering insights into publication patterns, key contributors, thematic evolution, and
Adelina Zeqiri   +2 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Electoral platforms, implemented policies and abstention [PDF]

open access: yes
Recent studies of American politics evidence that political polarization of both the electorate and the political elite have moved 'almost in tandem for the past half century' (McCarty et al., 2003, p.2), and that party polarization has steadily ...
Humberto Llavador
core  

Layered Network Diffusion of Misinformation on YouTube: A Multi-Level Analysis of Video and Channel Interactions

open access: yesPlatforms
Misinformation has become a persistent feature of contemporary digital information environments. Platform designs and business models often privilege attention, engagement, and repeated exposure over epistemic quality.
Md Irfanuzzaman Khan   +2 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Bioerosion on shore platforms developed in the Waitemata Formation, Auckland [PDF]

open access: yes, 1968
Bioerosion - the removal of lithic substrate by the erosive activities of living organisms- has not previously been discussed for New Zealand shore platforms.
Healy, T.R., Healy, Terry R.
core  

Modernizing Middleware Platforms: Strategies, Challenges and Opportunities

open access: yes, 2023
: Middleware platforms are key components that bridge the gap between heterogenous information systems and enable the flow of real time data between applications within and across organizations in order to achieve seamless and efficient business ...
Afnan Alawami
core   +1 more source

How Live Streaming Commerce Platforms Drive Consumer Purchase Intention: Dual Mediation of Trust and Perceived Value in a UK Sample

open access: yesPlatforms
Live streaming commerce delivers conversion rates up to ten times higher than conventional online stores, yet research on the psychological mechanisms behind that lift has tested platform features in isolation, through single-mediator pathways.
Georgios Tsimonis
doaj   +1 more source

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