Results 51 to 60 of about 625,438 (268)

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

The Use of Digital Twins to Address Smart Tourist Destinations’ Future Challenges

open access: yesPlatforms
This research aims to conceptualise the use of the digital twins (DT) tool in tourism to address smart tourist destinations’ future challenges to enhance tourists’ experiences and residents’ quality of life through better services developed by DTs.
Lázaro Florido-Benítez
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

DDMMO Website Quality, Destination Image and Intention to Use Metaverse Platforms

open access: yesPlatforms
Background/Objectives: Destination Development, Management, and Marketing Organizations (DDMMOs) have the power to influence perceptions and behaviors regarding both actual and virtual travel in the rapidly changing landscape of digital environments ...
Georgios A. Deirmentzoglou   +2 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Green Taxation, Urban Investment Platform Debt, and Urban Green Transformation

open access: yesPlatforms
Green development serves as the foundation for high-quality development. As one of the most commonly used macroeconomic regulation policies, taxation is a crucial component of the modernization of the national governance system and governance capacity ...
Haiyang Zhou   +4 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Digital Intermediation and Precarity: Experiences of Domestic Workers in Chile’s Platform Labor Economy

open access: yesPlatforms
This article explores the implications of digital labor intermediation platforms in paid domestic work (PDW) in Chile, a sector historically marked by informality and vulnerability.
Rosa Villarroel-Valdés   +2 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Driving Strategic Innovation Through AI Adoption in Government Financial Regulators: A Case Study

open access: yesPlatforms
Public institutions are experiencing increased dynamism due to rapid technological development and digitalization, which are creating novel opportunities for innovation.
Carlos Andrés Merlano Porras   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy