Results 81 to 90 of about 928,606 (352)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Microscaled and nanoscaled platinum sensors [PDF]

, 2010
We show small and robust platinum resistive heaters and thermometers that are defined by microlithography on silicon substrates. These devices can be used for a wide range of applications, including thermal sensor arrays, programmable thermal sources ...
Chen, Samson, Guo, Luke, Gwinn, Tom, Rajagopal, Aditya, Scherer, Axel, Walavalkar, Sameer S.   +5 more
core  

A systematic review of platinum and taxane resistance from bench to clinic: an inverse relationship [PDF]

, 2007
We undertook a systematic review of the pre-clinical and clinical literature for studies investigating the relationship between platinum and taxane resistance.
Davey, Ross, Pavlakis, Nick, Stordal, Britta   +2 more
core   +1 more source

A High‐Sensitivity Circulating Nucleic Acid Sequencing Assay for Assessing Treatment Response to Alectinib in a Pediatric Patient With ALK‐Rearranged Non–Small Cell Lung Cancer

Pediatric Blood &Cancer, EarlyView.
Alberto D. Guerra, Nicholas F. Evageliou, Vandana Batra, Kristen L. Dalton, Stephanie Ortel, Usman Ashraf, Tricia R. Bhatti, Lisa J. States, Lea F. Surrey, Theodore W. Laetsch   +9 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Oxygen reduction reaction on Pt/C at the presence of super paramagnetic of Fe3O4 nanoparticles for PEMFCs [PDF]

Hydrogen, Fuel Cell & Energy Storage, 2014
In this paper the role of super paramagnetic iron oxide nanoparticles (SPI) on Platinum nanoclusters on activated carbon (Pt/C) for electrocatalytic oxygen reduction reaction was considered.
Mehdi Kheirmand, Freshteh Rastegari-fard
doaj   +1 more source

Discovery of Calcium, Indium, Tin, and Platinum Isotopes

, 2010
Currently, twenty-four calcium, thirty-eight indium, thirty-eight tin and thirty-nine platinum isotopes have been observed and the discovery of these isotopes is discussed here.
Albouy, Aleklett, Alvager, Amaldi, Anderson, Arblaster, Aston, Aston, Aston, Aston, Aston, Audi, Baranov, Barnes, Barnes, Bassani, Batzel, Beraud, Bernas, Bernas, Bingham, Bogdanov, Borg, Burminskii, Burminskii, Catura, Chang, Cline, Cork, Cork, Cork, Davidson, Dempster, Dempster, Deneffe, der Mateosian, Diamond, Dillmann, Dropesky, Duckworth, Duffield, Ehmann, Facetti, Fritze, Fränz, Fränz, Fuchs, Gauvin, Ghoshal, Ginepro, Goriely, Grapengiesser, Greendale, Grummitt, Grummitt, Grunder, Hagebo, Hardy, Hardy, Hinshaw, Hoff, Hofmann, Hseuh, Huber, Huck, Huck, Huyse, Inamura, Izak, J.L. Gross, Kantele, Karras, Kavanagh, Kerek, Kerek, Khulelidze, Kurcewicz, Kurtukian-Nieto, Langevin, Lawson, Lawson, Leander, Lewitowicz, Lhersonneau, Lindner, Lindner, Livingood, Livingood, Livingood, Lund, M. Thoennessen, Mallary, Malysheva, Mantica, Matthews, Mayer, McGinnis, McGinnis, McLennan, McMillan, Mead, Nahmias, Naidu, Naumann, Negra, Nier, Nussis, Pappa, Petroff, Petroff, Podolyak, Pool, Reeder, Rivier, Rivier, Rougny, Roy, S. Amos, Schneider, Seren, Shalev, Shi, Shida, Siivola, Smith, Steer, Steer, Strom, Tarasov, Tendam, Thoennessen, Thompson, Thomson, Tidemand-Petersson, Tribble, Varley, Walke, Wehrli, Wehrli, Wilkinson, Yamazaki, Yamazaki, Yuta, Äystö   +143 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Vapor-deposited platinum as a fuel-cell catalyst [PDF]

, 1974
Electrodes are prepared by vacuum deposition of platinum on nickel substrate with conventional vapor-deposition apparatus. Amount of platinum loaded on substrate can be veried by changing exposure time during deposition.
Asher, W. J., Batzold, J. S.
core   +1 more source

Scaling of Electrode-Electrolyte Interface Model Parameters In Phosphate Buffered Saline [PDF]

, 2014
We report how the impedance presented by a platinum electrode scales with the concentration of phosphate buffered saline (PBS). We find that the constant phase element of the model scales with approximately the log of concentration, whereas the ...
Jones, Mark Hedley, Scott, Jonathan B.
core   +2 more sources